Zobrazeno 1 - 10
of 29
pro vyhledávání: '"J R, Kuipers"'
Publikováno v:
Pediatric Research. 34:471-477
Myocardial oxygen demand may be increased in chronically hypoxemic lambs because of their increased heart rate. Therefore, we determined whether left ventricular (LV) oxygen supply, oxygen uptake and oxygen demand were proportionally increased in 6-w
Autor:
M Dalinghaus, J. J. Meuzelaar, J H Koers, A M Gerding, J. W. C. Gratama, W. G. Zijlstra, J R Kuipers
Publikováno v:
Journal of Clinical Investigation. 90:1745-1752
A left-to-right shunt is accompanied by an increased plasma and blood volume. Since this is likely realized through renin/aldosterone-mediated salt and water retention, other body fluid compartments may be changed too. Therefore, we studied blood vol
Publikováno v:
Biochemical Society transactions. 29(Pt 2)
Metabolic changes at around the time of birth are crucial for life. Here we review the energy utilization in the myocardium, emphasizing ketone body metabolism. Before birth, glucose and lactate are the major energy substrates for the myocardium. Lon
Publikováno v:
Advances in experimental medicine and biology. 466
Several severe congenital cardiomyopathies are known to be associated with deficiencies in long-chain fatty acid transport and oxidation. Our studies are focused on a key enzyme in the regulation of intracellular long-chain fatty acid transport: carn
Publikováno v:
Journal of mass spectrometry : JMS. 33(4)
Substrate oxidation by various organs in animals as well as in humans is usually studied by experiments in which radioactively labeled substrates are used and the production of 14CO2 is measured. In vivo, substrate oxidation by an organ has, up to no
Autor:
J R, Kuipers
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 137(25)
Myocardial carbohydrate, ketone, and fatty acid uptake in conscious lambs with aortopulmonary shunts
Autor:
J W, Gratama, M, Dalinghaus, J J, Meuzelaar, A M, Gerding, J H, Koers, F A, Muskiet, J R, Kuipers
Publikováno v:
Pediatric research. 32(1)
A left to right shunt increases myocardial work and is often accompanied by increased catecholamine levels. Because both increased myocardial work and increased catecholamine levels may induce increased fatty acid utilization, which could increase re
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Publikováno v:
Thoraxchirurgie, vaskulare Chirurgie. 22(4)
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 129(9)