Zobrazeno 1 - 10
of 112
pro vyhledávání: '"J R, HUDSON"'
Autor:
Jessica J. R. Hudson, Ulrich Rass
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 3984 (2021)
The conserved nuclease-helicase DNA2 has been linked to mitochondrial myopathy, Seckel syndrome, and cancer. Across species, the protein is indispensable for cell proliferation. On the molecular level, DNA2 has been implicated in DNA double-strand br
Externí odkaz:
https://doaj.org/article/eb1e4cc0ffb748999259dbe875fd39f0
Autor:
Jessica J R Hudson, Katerina Bednarova, Lucie Kozakova, Chunyan Liao, Marc Guerineau, Rita Colnaghi, Susanne Vidot, Jaromir Marek, Sreenivas R Bathula, Alan R Lehmann, Jan Palecek
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17270 (2011)
The SMC5-6 protein complex is involved in the cellular response to DNA damage. It is composed of 6-8 polypeptides, of which Nse1, Nse3 and Nse4 form a tight sub-complex. MAGEG1, the mammalian ortholog of Nse3, is the founding member of the MAGE (mela
Externí odkaz:
https://doaj.org/article/4f1de5e8a09e4934a044c2ab47f7b49f
Publikováno v:
Cell Cycle. 5:702-708
Repair of DNA double strand breaks (DSBs) is critical for the maintenance of genome integrity. DNA DSBs can be repaired by either homologous recombination (HR) or nonhomologous end-joining (NHEJ). Whilst HR requires sequences homologous to the damage
Autor:
Natasha V. Zhukovskaya, Nicholas D. Lakin, Duen-Wei Hsu, Po-Hsien Liu, Jeffrey G. Williams, Jessica J. R. Hudson, Kunde Guo, Catherine J. Pears
Publikováno v:
Current Biology. 15(20):1880-1885
Summary DNA double-strand breaks (DSBs) can be repaired by either homologous recombination (HR) or nonhomologous end-joining (NHEJ) [1]. In vertebrates, the first step in NHEJ is recruitment of the DNA-dependent protein kinase (DNA-PK) to DNA termini
Autor:
H. F. Linskens, M. V. Tracey, Ulrich Beiss, Fay Bendall, Walter Björk, F. Bohlmann, Hans G. Boman, Richard Braun, W. Heinen, Manfred Hesse, Eduard Hofmann, J. R. Hudson, Rüdiger Knapp, Rudolf Lambert, Carlos O. Miller, Gerhard Pfleiderer, B. D. Sanwal, Hans Schmid, Shoji Shibata, Herbert Stern, Wolfgang Sucrow, Josef Tobiška, F. W. Zilliken
Publikováno v:
Journal of Animal Science. 72:903-910
A fragment of a bovine myosin heavy-chain (MHC) gene approximately 15 kbp in size (designated MHC 67) was isolated from a bovine genomic DNA library. The direction of transcription was determined, and preliminary experiments indicated that the gene w
Autor:
C. Anne-Marie Couto, Christine Borer, Rhian Kiely, Duen-Wei Hsu, Nicholas D. Lakin, Hong-Yu Wang, Jessica J. R. Hudson, Catherine J. Pears
Publikováno v:
Journal of cell science. 124(Pt 10)
DNA double-strand breaks (DSBs) can be repaired by homologous recombination (HR) or non-homologous end joining (NHEJ). The mechanisms that govern whether a DSB is repaired by NHEJ or HR remain unclear. Here, we characterise DSB repair in the amoeba D
Autor:
J R, HUDSON
Publikováno v:
The Veterinary record. 59(25)
Autor:
J. R. Hudson, David Botstein, James O. Armitage, Truc Tran, Patrick O. Brown, Ronald Levy, W. C. Chan, Liming Yang, Louis M. Staudt, Gerald E. Marti, D. T. Moore, Ruth E. Davis, Michael B. Eisen, John Powell, Ash A. Alizadeh, Chi Ma, Izidore S. Lossos, Hajeer Sabet, D. D. Weisenburger, Timothy C. Greiner
Publikováno v:
Cold Spring Harbor symposia on quantitative biology. 64
Publikováno v:
Cancer research. 59(22)
The development and use of molecular-based therapy for breast cancer and other human malignancies will require a detailed molecular genetic analysis of patient tissues. The recent development of laser capture microdissection and high density cDNA arr