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pro vyhledávání: '"J R, Friend"'
Autor:
W S, Hu, J R, Friend, F J, Wu, T, Sielaff, M V, Peshwa, A, Lazar, S L, Nyberg, R P, Remmel, F B, Cerra
Publikováno v:
Cytotechnology. 23(1-3)
Liver failure is a major cause of mortality. A bioartificial liver (BAL) employing isolated hepatocytes can potentially provide temporary support for liver failure patients. We have developed a bioartificial liver by entrapping hepatocytes in collage
Publikováno v:
Methods in molecular medicine. 18
Several investigators have demonstrated that freshly harvested hepatocytes self-assemble into three-dimensional, compacted, freely suspended aggregates known as spheroids (1-3). These aggregates have smooth, undulating surfaces and average approx 120
Publikováno v:
Methods in molecular medicine. 18
Liver disease continues to be a challenge clinically, with 30,000 patients dying each year from liver failure (1). Although liver transplantation can successfully treat many patients undergoing liver failure, the scarcity of donor organs severely lim
Autor:
J R, Friend
Publikováno v:
Hospital medicine (London, England : 1998). 59(9)
Publikováno v:
Biotechnology and bioengineering. 52(1)
A xenogeneic hollow fiber bioreactor utilizing collagen-entrapped dispersed hepatocytes has been developed as an extracorporeal bioartificial liver (BAL) for potential treatment of acute human fulminant hepatitis. Prolonged viability, enhanced liver-
Publikováno v:
Biotechnology and bioengineering. 50(4)
Freshly harvested primary rat hepatocytes cultivated as multicellular aggregates, or spheroids, have been observed to exhibit enhanced liver-specific function and differentiated morphology compared to cells cultured as monolayers. An efficient method
Publikováno v:
The British journal of radiology. 64(766)
We report a case of the haemolysis, elevated liver enzymes, low platelets (HELLP) syndrome in a primigravida, in whom ultrasound examination demonstrated large, “geographical” areas of increased echogenicity within the right lobe of the liver. Ha
Publikováno v:
BMJ. 1:434-437
Successful therapeutic abortion was performed consecutively by an intra-amniotic injection of hypertonic saline in 102 out of 110 patients in whom the size of the uterus corresponded with a pregnancy of 16 weeks or more. A spontaneous abortion of the
Autor:
J R, Friend
Publikováno v:
American journal of hospital pharmacy. 41(9)
Publikováno v:
American journal of pharmaceutical education. 50(2)
The University of Toledo College of Pharmacy has developed a multi-facetted and dynamic system for evaluation of its Externship Program. The initial data base consisted of evaluation responses for individual externs, externship sites, and the perform