Zobrazeno 1 - 10
of 172
pro vyhledávání: '"J R, Fletcher"'
Autor:
A. D. Reed, J. R. Fletcher, Y. Y. Huang, R. Thanissery, A. J. Rivera, R. J. Parsons, A. K. Stewart, D. J. Kountz, A. Shen, E. P. Balskus, C. M. Theriot
Publikováno v:
mSphere, Vol 7, Iss 2 (2022)
ABSTRACT An intact gut microbiota confers colonization resistance against Clostridioides difficile through a variety of mechanisms, likely including competition for nutrients. Recently, proline was identified as an important environmental amino acid
Externí odkaz:
https://doaj.org/article/14ceeff9285f45de842391279dba1aea
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 4, Pp n/a-n/a (2021)
Abstract Parkinson's disease is a highly disabling, progressive neurodegenerative disease that manifests as a mix of motor and non‐motor signs. Although we are equipped with some symptomatic treatments, especially for the motor signs of the disease
Externí odkaz:
https://doaj.org/article/f730110fd360437a87b9a098a3eff3ee
Publikováno v:
BMC Neuroscience, Vol 20, Iss 1, Pp 1-10 (2019)
Abstract Background Parkinson’s disease (PD) is characterised by dopaminergic cell loss within the substantia nigra pars compacta (SNc) that leads to reduced striatal dopamine content and resulting motor deficits. Identifying new strategies to prot
Externí odkaz:
https://doaj.org/article/bc2b3464a17249d2937c80ef13208d7f
Autor:
Emily Clarke, Pawel Stocki, Elizabeth H. Sinclair, Aziz Gauhar, Edward J. R. Fletcher, Alicja Krawczun-Rygmaczewska, Susan Duty, Frank S. Walsh, Patrick Doherty, Julia Lynn Rutkowski
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1335 (2022)
Single domain shark antibodies that bind to the transferrin receptor 1 (TfR1) on brain endothelial cells have been used to shuttle antibodies and other cargos across the blood brain barrier (BBB) to the brain. For these studies the TXB4 brain shuttle
Externí odkaz:
https://doaj.org/article/7e8201a7d0904e04a5f05e9349a1bc37
Autor:
Edward J. R. Fletcher, Clare J. Finlay, Ana Amor Lopez, William R. Crum, Anthony C. Vernon, Susan Duty
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Dyskinesia associated with chronic levodopa treatment in Parkinson’s disease is associated with maladaptive striatal plasticity. The objective of this study was to examine whether macroscale structural changes, as captured by magnetic resonance ima
Externí odkaz:
https://doaj.org/article/728b6f2a2ad5471b9a03e5fa63346c57
Autor:
O A James, A Sole-Guitart, B M Forde, J R Fletcher, Carlos E. Medina-Torres, Ka Y. Yuen, Justine S. Gibson, Alex C. Young, Allison J. Stewart
Publikováno v:
Australian Veterinary Journal. 100:107-113
BACKGROUND Chronic oroantral fistulae (OAF) with secondary sinusitis can occur following repulsion of cheek teeth in horses. CASE REPORT An 8-year-old Andalusian cross gelding presented with an iatrogenic clinical crown fracture of tooth 209, which u
Publikováno v:
Neuronal Signaling
Parkinson’s disease (PD) is a complex, multisystem disorder characterised by α-synuclein (SNCA) pathology, degeneration of nigrostriatal dopaminergic neurons, multifactorial pathogenetic mechanisms and expression of a plethora of motor and non-mot
Publikováno v:
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives, Vol 9, Iss 4, Pp n/a-n/a (2021)
Pharmacology Research & Perspectives, Vol 9, Iss 4, Pp n/a-n/a (2021)
Parkinson's disease is a highly disabling, progressive neurodegenerative disease that manifests as a mix of motor and non‐motor signs. Although we are equipped with some symptomatic treatments, especially for the motor signs of the disease, there a
Autor:
Francois-Rene Bertin, Annie Rose, Helen Owen, Natalie S. Fraser, J. R. Fletcher, Allison J. Stewart
Publikováno v:
Equine Veterinary Education. 33
Publikováno v:
BMC Neuroscience
BMC Neuroscience, Vol 20, Iss 1, Pp 1-10 (2019)
BMC Neuroscience, Vol 20, Iss 1, Pp 1-10 (2019)
Background Parkinson’s disease (PD) is characterised by dopaminergic cell loss within the substantia nigra pars compacta (SNc) that leads to reduced striatal dopamine content and resulting motor deficits. Identifying new strategies to protect these