Zobrazeno 1 - 10
of 74
pro vyhledávání: '"J R, FOUTS"'
Autor:
J R Fouts, J E A Leakey
Publikováno v:
Biochemical Journal. 182:233-235
Intraperitoneal injection of neonatal rats with glucocorticoid hormones causes precocious development of hepatic cytochrome P-450. Glucagon injection fails to stimulate this cytochrome P-450 development. Adult liver cytochrome P-450 is less responsiv
Autor:
T R, Devereux, J R, Fouts
Publikováno v:
Methods in enzymology. 77
Publikováno v:
Biochemical Society transactions. 8(3)
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 12(1)
Epidermal cells in suspension were prepared from the skin of hairless mice by digestion of skin strips with pronase. The viability of cells in such suspensions was routinely greater than 75%. Fractions enriched in different cell types were prepared f
Autor:
R J, Pohl, J R, Fouts
Publikováno v:
Cancer research. 43(8)
Homogenates of Zymbal's glands from beta-naphthoflavone-treated rats and mice have 7-ethoxycoumarin O-deethylase activity, while those from rats also have aryl hydrocarbon hydroxylase activity. Measured concentrations of cytochrome P-450 in microsome
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 4(1)
The postnatal development of aminopyrine N-demethylase, aniline 4-hydroxylase, benzpyrene hydroxylase, biphenyl 4-hydroxylase, 7-ethoxycoumarin 0-deethylase activities, NADPH-cytochrome c reductase, and cytochrome P-450 was compared in microsomes fro
Autor:
J R, Bend, B R, Smith, L M, Ball, J L, Plummer, C R, Wolf, R M, Philpot, T R, Devereux, J R, Fouts
Publikováno v:
Advances in experimental medicine and biology.
For several years our laboratory has been investigating the biotransformation of various environmental pollutants by lung. Studies have been performed with pulmonary subcellular fractions, purified monooxygenase and glutathione transferase enzymes, a
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 225(2)
An investigation of several pathways for xenobiotic metabolism in rat lung cells was carried out using enriched fractions of alveolar type II cells (80% purity) and Clara cells (50% purity) which had been prepared from either untreated (control) rats
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 4(5)
A microsomal fraction, prepared from mouse skin, catalyzed the hydroxylation of benzpyrene and aniline and the deethylation of 7-ethoxycoumarin. Contamination of the preparation by cytochrome oxidase and cytochrome P-420 was determined by spectral an
Publikováno v:
Cancer research. 46(10)
Alveolar type II cells were isolated from five human lung specimens obtained during resection or lobectomy and enriched to 63-85% purity. Digestion with Sigma protease type XIV followed by centrifugal elutriation and Percoll density gradient centrifu