Human MAIT Cells Respond to Staphylococcus aureus with Enhanced Anti-Bacterial Activity

Autor: Andrew J. R. Cooper, Jonah Clegg, Féaron C. Cassidy, Andrew E. Hogan, Rachel M. McLoughlin

Publikováno v: Microorganisms, Vol 10, Iss 1, p 148 (2022)

Mucosal-Associated Invariant T (MAIT) cells have been shown to play protective roles during infection with diverse pathogens through their propensity for rapid innate-like cytokine production and cytotoxicity. Among the potential applications for MAI

Externí odkaz: https://doaj.org/article/6340cf9a190c412d94711724563bf68e

Broadly neutralizing antibodies target the coronavirus fusion peptide

Autor: Cherrelle Dacon, Courtney Tucker, Linghang Peng, Chang-Chun D. Lee, Ting-Hui Lin, Meng Yuan, Yu Cong, Lingshu Wang, Lauren Purser, Jazmean K. Williams, Chul-Woo Pyo, Ivan Kosik, Zhe Hu, Ming Zhao, Divya Mohan, Andrew J. R. Cooper, Mary Peterson, Jeff Skinner, Saurabh Dixit, Erin Kollins, Louis Huzella, Donna Perry, Russell Byrum, Sanae Lembirik, David Drawbaugh, Brett Eaton, Yi Zhang, Eun Sung Yang, Man Chen, Kwanyee Leung, Rona S. Weinberg, Amarendra Pegu, Daniel E. Geraghty, Edgar Davidson, Iyadh Douagi, Susan Moir, Jonathan W. Yewdell, Connie Schmaljohn, Peter D. Crompton, Michael R. Holbrook, David Nemazee, John R. Mascola, Ian A. Wilson, Joshua Tan

Publikováno v: Science. 377:728-735

The potential for future coronavirus outbreaks highlights the need to broadly target this group of pathogens. We used an epitope-agnostic approach to identify six monoclonal antibodies that bind to spike proteins from all seven human-infecting corona

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00be51410add1f540a8cd59d08b048c3
https://doi.org/10.1126/science.abq3773

A Proteomic Investigation of Hepatic Resistance to Ascaris in a Murine Model.

Autor: Gwendoline Deslyper, Thomas J Colgan, Andrew J R Cooper, Celia V Holland, James C Carolan

Publikováno v: PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004837 (2016)

The helminth Ascaris causes ascariasis in both humans and pigs. Humans, especially children, experience significant morbidity including respiratory complications, growth deficits and intestinal obstruction. Given that 800 million people worldwide are

Externí odkaz: https://doaj.org/article/2b76ff06b07a4a9ea8b02d604fa8a3a7

Locating the pseudogap closing point in cuprate superconductors: Absence of entrant or reentrant behavior

Autor: J. R. Cooper, John Loram, Jeffery L. Tallon, James Storey

Current descriptions of the pseudogap in underdoped cuprates envision a doping-dependent transition line $T^*(p)$ which descends monotonically towards zero just beyond optimal doping. There is much debate as to the location of the terminal point $p^*

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981317afee5f1cced022f3171607fc1a

Incoherent transport across the strange-metal regime of overdoped cuprates

Autor: Y. K. Huang, Sven Friedemann, Jan Zaanen, Nigel E. Hussey, Tsunehiro Takeuchi, Maarten Berben, Jake Ayres, Yu-Te Hsu, Takeshi Kondo, Carsten Putzke, Antony Carrington, Matija Čulo, J. R. Cooper, E. van Heumen

Publikováno v: Nature
Nature, 595, 661-666. NATURE RESEARCH
Nature, 595, 661-666
Nature, 595, pp. 661-666
Nature, 595(7869), 661-666. Nature Publishing Group

Strange metals possess highly unconventional transport characteristics, such as a linear-in-temperature ($T$) resistivity, an inverse Hall angle that varies as $T^2$ and a linear-in-field ($H$) magnetoresistance. Identifying the origin of these colle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42a32fb671e85501173a47893f5c0a59