Zobrazeno 1 - 10
of 2 040
pro vyhledávání: '"J Platt"'
Autor:
Avinash Aujayeb, Rachel Prichard, S Park, Mark A Baxter, J Hamilton, H Ali, L Hannington, Conor O'Neill, J Platt, G Clements, Deborah Scott, R Heywood, Helen Dearden, Sally Martin, Michael Rowe, Kieran Zucker, Clair Brunner, Adam L Peters, Maria Rohan, Alexandra Marsh, Abigail L Gee, Gemma Quesne, Jonny Heseltine, Joni Howells, Veronica Conteh, Xiangfei Yan, Lisa J Rodgers, J Grech, S McInerney, S Kingdon, L Eastlake, R Bryce, D Parslow, V Cope, N Aziz
Publikováno v:
BMJ Oncology, Vol 3, Iss 1 (2024)
Objective The Cancer and Aging Research Group (CARG) score was developed to predict severe chemotherapy-induced toxicity risk in older adults; validation study results have varied. The Tolerance of Anti-cancer Systemic Therapy in the Elderly study so
Externí odkaz:
https://doaj.org/article/30744de9a2794c768c87e2ba9b482a00
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Molecular screens comparing different disease states to identify candidate genes rely on the availability of fast, reliable and multiplexable systems to interrogate genes of interest. CRISPR/Cas9-based reverse genetics is a promising method
Externí odkaz:
https://doaj.org/article/7fd74c1a9e8f44f68884782a4b513558
Publikováno v:
Health Technology Assessment, Vol 8, Iss 20 (2004)
Externí odkaz:
https://doaj.org/article/9faf0517e83d40fcab8355d2d78ccbcf
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Bacterial communities associated with vegetation-soil interfaces have important roles in terrestrial ecosystems. These bacterial communities, studied almost exclusively in unburnt ecosystems or those affected by rare, high-intensity wildfire
Externí odkaz:
https://doaj.org/article/33c9693ffb9445fda0614503b5323989
Autor:
Catherine R. Hanna, Sean M. O’Cathail, Janet S. Graham, Mark Saunders, Leslie Samuel, Mark Harrison, Lynsey Devlin, Joanne Edwards, Daniel R. Gaya, Caroline A. Kelly, Liz-Anne Lewsley, Noori Maka, Paula Morrison, Louise Dinnett, Susan Dillon, Jacqueline Gourlay, Jonathan J. Platt, Fiona Thomson, Richard A. Adams, Campbell S. D. Roxburgh
Publikováno v:
Radiation Oncology, Vol 16, Iss 1, Pp 1-9 (2021)
Abstract Background Advances in multi-modality treatment of locally advanced rectal cancer (LARC) have resulted in low local recurrence rates, but around 30% of patients will still die from distant metastatic disease. In parallel, there is increasing
Externí odkaz:
https://doaj.org/article/868a94dd8de84d4ca5757841bb549fda
Autor:
Ellis Q. Margolis, Christopher H. Guiterman, Raphaël D. Chavardès, Jonathan D. Coop, Kelsey Copes‐Gerbitz, Denyse A. Dawe, Donald A. Falk, James D. Johnston, Evan Larson, Hang Li, Joseph M. Marschall, Cameron E. Naficy, Adam T. Naito, Marc‐André Parisien, Sean A. Parks, Jeanne Portier, Helen M. Poulos, Kevin M. Robertson, James H. Speer, Michael Stambaugh, Thomas W. Swetnam, Alan J. Tepley, Ichchha Thapa, Craig D. Allen, Yves Bergeron, Lori D. Daniels, Peter Z. Fulé, David Gervais, Martin P. Girardin, Grant L. Harley, Jill E. Harvey, Kira M. Hoffman, Jean M. Huffman, Matthew D. Hurteau, Lane B. Johnson, Charles W. Lafon, Manuel K. Lopez, R. Stockton Maxwell, Jed Meunier, Malcolm North, Monica T. Rother, Micah R. Schmidt, Rosemary L. Sherriff, Lauren A. Stachowiak, Alan Taylor, Erana J. Taylor, Valerie Trouet, Miguel L. Villarreal, Larissa L. Yocom, Karen B. Arabas, Alexis H. Arizpe, Dominique Arseneault, Alicia Azpeleta Tarancón, Christopher Baisan, Erica Bigio, Franco Biondi, Gabriel D. Cahalan, Anthony Caprio, Julián Cerano‐Paredes, Brandon M. Collins, Daniel C. Dey, Igor Drobyshev, Calvin Farris, M. Adele Fenwick, William Flatley, M. Lisa Floyd, Ze'ev Gedalof, Andres Holz, Lauren F. Howard, David W. Huffman, Jose Iniguez, Kurt F. Kipfmueller, Stanley G. Kitchen, Keith Lombardo, Donald McKenzie, Andrew G. Merschel, Kerry L. Metlen, Jesse Minor, Christopher D. O'Connor, Laura Platt, William J. Platt, Thomas Saladyga, Amanda B. Stan, Scott Stephens, Colleen Sutheimer, Ramzi Touchan, Peter J. Weisberg
Publikováno v:
Ecosphere, Vol 13, Iss 7, Pp n/a-n/a (2022)
Abstract Fire regimes in North American forests are diverse and modern fire records are often too short to capture important patterns, trends, feedbacks, and drivers of variability. Tree‐ring fire scars provide valuable perspectives on fire regimes
Externí odkaz:
https://doaj.org/article/bffe42f20ce64323910ed51e32571ed8
Publikováno v:
eLife, Vol 10 (2021)
Class A G-protein-coupled receptors (GPCRs) normally function as monomers, although evidence from heterologous expression systems suggests that they may sometimes form homodimers and/or heterodimers. This study aims to evaluate possible functional in
Externí odkaz:
https://doaj.org/article/20dbf07498384c35b243ba1bdb96de64
Autor:
Sarah Threlfell, Amir Saeid Mohammadi, Brent J. Ryan, Natalie Connor-Robson, Nicola J. Platt, Rishi Anand, Florence Serres, Trevor Sharp, Nora Bengoa-Vergniory, Richard Wade-Martins, Andrew Ewing, Stephanie J. Cragg, Katherine R. Brimblecombe
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Striatal dopamine transporters (DAT) powerfully regulate dopamine signaling, and can contribute risk to degeneration in Parkinson’s disease (PD). DATs can interact with the neuronal protein α-synuclein, which is associated with the etiology and mo
Externí odkaz:
https://doaj.org/article/d94e14e6aa624a13a530f30f01d4e044
Autor:
Jon M. Madison, Karen Duong, Ellen F. Vieux, Namrata D. Udeshi, Sumaiya Iqbal, Elise Requadt, Shaunt Fereshetian, Michael C. Lewis, Antonio S. Gomes, Kerry A. Pierce, Randall J. Platt, Feng Zhang, Arthur J. Campbell, Dennis Lal, Florence F. Wagner, Clary B. Clish, Steven A. Carr, Morgan Sheng, Edward M. Scolnick, Jeffrey R. Cottrell
Publikováno v:
iScience, Vol 24, Iss 1, Pp 101935- (2021)
Summary: Genetic variation of the 16p11.2 deletion locus containing the KCTD13 gene and of CUL3 is linked with autism. This genetic connection suggested that substrates of a CUL3-KCTD13 ubiquitin ligase may be involved in disease pathogenesis. Compar
Externí odkaz:
https://doaj.org/article/02815da01a7f40da86fd1e72b7901ade
Autor:
Jonathan J. Miner, Derek J. Platt, Cyrus M. Ghaznavi, Pallavi Chandra, Andrea Santeford, Amber M. Menos, Zhenyu Dong, Erin R. Wang, Wei Qian, Elysse S. Karozichian, Jennifer A. Philips, Rajendra S. Apte
Publikováno v:
Cell Reports, Vol 33, Iss 5, Pp 108339- (2020)
Summary: Here, we report our studies of immune-mediated regulation of Zika virus (ZIKV), herpes simplex virus 1 (HSV-1), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the human cornea. We find that ZIKV can be transmit
Externí odkaz:
https://doaj.org/article/1d747a51c2e3423d93390f3b6d7ce502