Zobrazeno 1 - 10
of 268
pro vyhledávání: '"J Peynet"'
Autor:
Jean-Philippe Kevorkian, J. Peynet, T. Meas, Marie Virally, Marie Laloi-Michelin, V. Giraudeaux, Pierre-Jean Guillausseau
Publikováno v:
European Journal of Internal Medicine. 20:197-200
Interest of statins in terms of morbid-mortality reduction in primary and secondary prevention in type 2 diabetic patients has broadly been proven in recent studies, while evidence for fibrates preventive effect is considerably weaker. HMGCoA reducta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a888ab85934cc814faf43dd61beafcdf
https://doi.org/10.1016/j.ejim.2008.06.009
https://doi.org/10.1016/j.ejim.2008.06.009
Autor:
Dominique Bonnefont-Rousselot, Claudine Cosson, Nadjat Ouslimani, Meriem Mahrouf, Jean-Louis Beaudeux, Alain Legrand, J. Peynet
Publikováno v:
Metabolism. 56:308-313
Beyond its antihyperglycemic action, the antidiabetic oral drug metformin possesses antioxidant properties that may contribute to improve the cardiovascular deleterious effects of the diabetic disease. We explored whether metformin could modulate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d49b45ca264cec52495e41a010403cd
https://doi.org/10.1016/j.metabol.2006.10.010
https://doi.org/10.1016/j.metabol.2006.10.010
Autor:
C. Marchand, J. Peynet, Jean-Yves Artigou, A. Legrand, Dominique Bonnefont-Rousselot, Jean-Christophe Charniot, Khaled Zerhouni, M. Plotkine, N. Vignat
Publikováno v:
Free Radical Research. 41:424-431
This study aimed at evaluating OS in an amyotrophic quadricipital syndrome with cardiac impairment in a family of 80 members with a mutation in lamin A/C gene. Twelve patients had cardiac involvement (5 cardiac and skeletal muscles impairment). OS wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5096f933f47d53ea63150de4c38dc1e
https://doi.org/10.1080/10715760601110046
https://doi.org/10.1080/10715760601110046
Publikováno v:
Annales Pharmaceutiques Françaises. 64:373-381
Resume Les especes reactives de l’oxygene (ERO) et de l’azote (ERN) produites par les cellules ont ete longtemps vues comme des produits toxiques du metabolisme pouvant alterer les constituants lipidiques, proteiques ou le DNA de la cellule. Tout
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d525f026a8ce41b133893ec05db01ab
https://doi.org/10.1016/s0003-4509(06)75332-9
https://doi.org/10.1016/s0003-4509(06)75332-9
Autor:
Raja Djelidi, J. Peynet, Patrice Thérond, Nadjat Ouslimani, M. Mahrouf, Martine Couturier, Jean-Louis Beaudeux, Alain Legrand
Publikováno v:
Biochemical Pharmacology. 72:176-183
Oxidative stress plays a major role in the pathogenesis and in the onset of macrovascular complications of diabetes. We previously reported that the antihyperglycaemic drug metformin was able to decrease significantly intracellular reactive oxygen sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c857582d83b2d4dcfd6aa860b09e4a3
https://doi.org/10.1016/j.bcp.2006.04.027
https://doi.org/10.1016/j.bcp.2006.04.027
Autor:
J.-L. Beaudeux, J. Delattre, J. Peynet, Dominique Bonnefont-Rousselot, P. Thérond, A. Legrand
Publikováno v:
Immuno-analyse & Biologie Spécialisée. 21:144-150
Resume Les especes reactives de l'oxygene (ERO) et de l'azote (ERN), radicalaires ou non radicalaires, sont produites en permanence par les types cellulaires constituant la paroi vasculaire. Cette synthese est assuree par differents systemes enzymati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1546057c583301b3c64b7bff7c6f3759
https://doi.org/10.1016/j.immbio.2006.02.001
https://doi.org/10.1016/j.immbio.2006.02.001
Autor:
J. Peynet, Nadjat Ouslimani, Jean-Louis Beaudeux, Patrice Thérond, Alain Legrand, Dominique Bonnefont-Rousselot
Publikováno v:
Metabolism. 54:829-834
Beyond its antidiabetic activity justifying its use in the treatment of the type 2 diabetes, metformin (MET [dimethylguanidine, Glucophage]) has been shown to exhibit antioxidant properties in vitro, which could contribute to limit the deleterious va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3386b4452b37e65eb39f41b4e7014f20
https://doi.org/10.1016/j.metabol.2005.01.029
https://doi.org/10.1016/j.metabol.2005.01.029
Publikováno v:
Annales Pharmaceutiques Françaises. 62:147-157
Chronic hyperglycemia in diabetes mellitus is an oxidative stress created by an imbalance of prooxidants over antioxidant defenses. The pathogenesis would involve several mechanisms including glucose autoxidation, protein glycation, the polyol pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9edfe81a1218a2a97d69b5b6f61aa566
https://doi.org/10.1016/s0003-4509(04)94297-6
https://doi.org/10.1016/s0003-4509(04)94297-6
Autor:
J. Peynet, Dominique Bonnefont-Rousselot, S. Walrand, M.P. Vasson, Alain Legrand, Daniel Jore, Monique Gardès-Albert, B. Raji
Publikováno v:
Metabolism. 52:586-589
Metformin (dimethylbiguanide) is an antihyperglycemic agent used in type 2 diabetes. Beyond its action on glycemic control, metformin exhibits other intrinsic effects that could play a role in prevention against diabetes complications. Some studies t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f77f01bd2ee23b9e5d768a05befd26a
https://doi.org/10.1053/meta.2003.50093
https://doi.org/10.1053/meta.2003.50093
Autor:
Patrice Thérond, Alain Legrand, Dominique Bonnefont-Rousselot, Jean-Louis Beaudeux, J. Peynet, J. Delattre
Publikováno v:
cclm. 37:939-948
The oxidative hypothesis of atherosclerosis classically implies a central role for low density lipoprotein (LDL) oxidation. However, new antiatherogenic properties have been recognized for high density lipoproteins (HDL), apart from their ability to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab6094afdbe29cc27d20c6ebd8c1fff8
https://doi.org/10.1515/cclm.1999.139
https://doi.org/10.1515/cclm.1999.139