Zobrazeno 1 - 10 of 22 pro vyhledávání: '"J Perschbacher"'
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Abstract 015: Reduced Placental Expression of Regulator of G Protein Signaling-2 (RGS2) in Preeclampsia: Association, Consequence, and Cause
Autor: Guorui Deng, Jeremy A. Sandgren, Eric J. Devor, Katherine N. Gibson-Corley, Gary L. Pierce, Justin L. Grobe, Rory A. Fisher, Donna A. Santillan, Katherine J Perschbacher, Mark K. Santillan
Publikováno v: Hypertension. 72
To date, the early-gestational mechanisms driving the pathogenesis of preeclampsia (PreE) remain largely unclear. However, altered G protein signaling has been implicated in PreE, including alterations in GPCR agonists such as vasopressin, endothelin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fced2e4f7c9568e7cd611a1b38d7e9b1
https://doi.org/10.1161/hyp.72.suppl_1.015
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Abstract P316: Effects of Paternal Contribution of a Null Allele of Regulator of G Protein Signaling-2 ( Rgs2 ) upon the Placental Transcriptome of C57BL/6J Mice
Autor: John W. Walsh, Guorui Deng, Eric J. Devor, Justin L. Grobe, Katherine N. Gibson-Corley, Donna A. Santillan, Gary L. Pierce, Curt D. Sigmund, Katherine J Perschbacher, Mark K. Santillan, Rory A. Fisher
Publikováno v: Hypertension. 72
Preeclampsia (PreE), a cardiovascular disorder of pregnancy, remains a major cause of maternal and fetal mortality worldwide. The early etiology of the disorder is unclear, though increased G protein-coupled receptor signaling has been implicated. Re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4dc6cddcf6a0eba6be357524942d803b
https://doi.org/10.1161/hyp.72.suppl_1.p316
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Regulators of G protein signaling in cardiovascular function during pregnancy
Autor: Mark K. Santillan, Katherine J Perschbacher, Guorui Deng, Justin L. Grobe, Rory A. Fisher, Katherine N. Gibson-Corley
Publikováno v: Physiological genomics. 50(8)
G protein-coupled receptor signaling mechanisms are implicated in many aspects of cardiovascular control, and dysfunction of such signaling mechanisms is commonly associated with disease states. Investigators have identified a large number of regulat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c7e376506f66fd0a73811a339f7606
https://pubmed.ncbi.nlm.nih.gov/29702036
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Abstract P256: Vasopressin Infusion During Pregnancy in Mice Induces Early Histological Placental Phenotypes of Preeclampsia
Autor: Jeremy A Sandgren, Katherine N Gibson-Corley, Danny W Linggonegoro, Katherine J Perschbacher, Shao Yang Zhang, Sabrina M Scroggins, Guorui Deng, Nicole A Pearson, Donna A Santillan, Gary L Pierce, Mark K Santillan, Curt D Sigmund, Justin L Grobe
Publikováno v: Hypertension. 70
Human preeclampsia (PE) is associated with elevated secretion of arginine vasopressin (AVP), and chronic infusion of AVP into pregnant mice is sufficient to model PE by causing hypertension, renal glomerular endotheliosis, proteinuria, fetal placenta
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6b6856cdef19f558892a2d3be86f6deb
https://doi.org/10.1161/hyp.70.suppl_1.p256
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Plný text Recenzováno Digitální knihovna AV ČR
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