Zobrazeno 1 - 10
of 86
pro vyhledávání: '"J Patrick O'Connor"'
Autor:
Jason T Maikos, John M Chomack, David V Herlihy, David N Paglia, Charlene Wetterstrand, J Patrick O'Connor, Michael J Hyre, J Peter Loan, Susan E D'Andrea
Publikováno v:
JMIR Research Protocols, Vol 13, p e57329 (2024)
BackgroundRelative motion between the residual limb and socket in individuals with transtibial limb loss can lead to substantial consequences that limit mobility. Although assessments of the relative motion between the residual limb and socket have b
Externí odkaz:
https://doaj.org/article/d36bebf1b945474aae88d7966a5d3284
Autor:
Hsuan-Ni Lin, J Patrick O'Connor
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88423 (2014)
This study investigated the localization of critical enzymes involved in arachidonic acid metabolism during the initial and regenerative phases of mouse femur fracture healing. Previous studies found that loss of cyclooxygenase-2 activity impairs fra
Externí odkaz:
https://doaj.org/article/60b007a196294bfcb7813b3b5ae4609a
Autor:
Yazan Kadkoy, Sangeeta Abraham, Peter Michael, Tasmima Tazin, Charlene Wetterstrand, J. Patrick O'Connor
Publikováno v:
Bone Reports, Vol 19, Iss , Pp 101726- (2023)
Estimating the mechanical properties of bone in vivo without destructive testing would be useful for research and clinical orthopedic applications. Micro-computerized tomography (μCT) imaging can provide quantitative, high-resolution 3D representati
Externí odkaz:
https://doaj.org/article/fbe8d6437ef24416968d7c44563476bf
Autor:
Alexis Hernandez MS, Ohidur Rahman BS, Yazan Kadkoy MS, Katherine L. Lauritsen BS, Alexandra Sanchez BA, Kevin Innella DO, Anthony Lin BA, J. Patrick O'Connor PhD, Joseph Benevenia MD, David Paglia PhD, Sheldon S. Lin MD, Jessica A. Cottrell PhD
Publikováno v:
Foot & Ankle Orthopaedics, Vol 7 (2022)
Category: Diabetes; Basic Sciences/Biologics; Trauma Introduction/Purpose: Prophylactic vancomycin treatment decreases the rates of surgical site and deep infections by >70% for diabetic patients undergoing reconstructive foot and ankle surgery. We a
Externí odkaz:
https://doaj.org/article/21ce2e8fffe14ee2a0f81851fbe91a6c
Autor:
Alexis Hernandez, Ohidur Rahman, Yazan Kadkoy, Katherine L. Lauritsen, Alexandra Sanchez, Kevin Innella, Anthony Lin, Jonathan Lopez, J. Patrick O’Connor, Joseph Benevenia, David N. Paglia, Sheldon S. Lin, Jessica Cottrell
Publikováno v:
Foot & Ankle International. 44:232-242
Background: Prophylactic vancomycin treatment decreases the prevalence of surgical site and deep infections by >70% in diabetic patients undergoing reconstructive foot and ankle surgery. Thus, determining whether clinically relevant local vancomycin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07b3173877cdb28f41db9021c7b08682
https://doi.org/10.1177/10711007231153354
https://doi.org/10.1177/10711007231153354
Autor:
Kevin Innella, Michael F. Levidy, Yazan Kadkoy, Anthony Lin, Marcus Selles, Alexandra Sanchez, Adam Weiner, Joshua Greendyk, Brian Moriarty, Katherine Lauritsen, Jonathan Lopez, Marc Teitelbaum, Mark Fisher, Dhruv Mendiratta, David B. Ahn, Joseph Ippolitto, David N. Paglia, Jessica Cottrell, J. Patrick O'Connor, Joseph Benevenia, Sheldon S. Lin
Publikováno v:
Journal of Orthopaedic Research.
The effects of locally applied zinc chloride (ZnCl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd784fc42581abdb73b0d6d22e99696
https://doi.org/10.1002/jor.25499
https://doi.org/10.1002/jor.25499
Autor:
J. Patrick O’Connor, Deboleena Kanjilal, Marc Teitelbaum, Sheldon S. Lin, Jessica A. Cottrell
Publikováno v:
Materials, Vol 13, Iss 10, p 2211 (2020)
Zinc is an essential mineral that is required for normal skeletal growth and bone homeostasis. Furthermore, zinc appears to be able to promote bone regeneration. However, the cellular and molecular pathways through which zinc promotes bone growth, ho
Externí odkaz:
https://doaj.org/article/8699244e31cb42b7b901c4cbbbe8d6d2
Autor:
Charlene Wetterstrand, Jeffrey Tompson, J. Patrick O'Connor, Spiro Moskonas, Deboleena Kanjilal, Anthony Lin, David N. Paglia, Maya Deza Culbertson, Yazan Kadkoy, Joseph Galloway
Publikováno v:
J Orthop Res
The effects of naproxen, a nonsteroidal anti-inflammatory drug (NSAID), on articular cartilage degeneration in female Sprague-Dawley rats was examined. Osteoarthritis (OA) was induced by destabilization of the medial meniscus (DMM) in each knee. Rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511f3954bbd7a0fd78c035866e514503
https://doi.org/10.1002/jor.24937
https://doi.org/10.1002/jor.24937
Autor:
Jessica Cottrell, J. Patrick O’Connor
Publikováno v:
Pharmaceuticals, Vol 3, Iss 5, Pp 1668-1693 (2010)
Nonspecific and COX-2 selective nonsteroidal anti-inflammatory drugs (NSAIDs) function by inhibiting the cyclooxygenase isoenzymes and effectively reduce pain and inflammation attributed to acute or chronic musculoskeletal pathologies. However, use o
Externí odkaz:
https://doaj.org/article/8109d6bb56884c75af98941b56a4fb59
Improved osteogenesis in rat femur segmental defects treated with human allograft and zinc adjuvants
Autor:
J. Patrick O'Connor, Maya Deza Culbertson, Joseph Benevenia, Deboleena Kanjilal, Michael J. Vives, Christopher Grieg, Sheldon S. Lin
Publikováno v:
Exp Biol Med (Maywood)
Bone allograft is widely used to treat large bone defects or complex fractures. However, processing methods can significantly compromise allograft osteogenic activity. Adjuvants that can restore the osteogenic activity of processed allograft should i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3351e2fa25f29c72f69874350ee3b97a
https://europepmc.org/articles/PMC8381705/
https://europepmc.org/articles/PMC8381705/
