Zobrazeno 1 - 10
of 25
pro vyhledávání: '"J Patrick, Condreay"'
Publikováno v:
Biological Safety
Accompanying the development of molecular biological tools for identifying gene sequences and functions has been the development of novel gene transfer vectors for shuttling gene sequences between different organisms. As illustrated in Fig. 1, a sear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6abc12373ffe1470b82624f4739a8b54
https://doi.org/10.1128/9781555819637.ch10
https://doi.org/10.1128/9781555819637.ch10
Autor:
Chuck Poole, Pierette Banker, Yu Guo, Gregory Schaaf, Tiffany Carpenter, Stephen A. Thomson, Dan Gillie, Curt D. Haffner, John C. Ulrich, Scott Howard Dickerson, Petrov Kimberly, J. Patrick Condreay, Jeff Gobel, Andrew L. Larkin
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:6989-6992
We report the synthesis and in vitro activity of a series of novel substituted N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs. These analogs showed potent inhibitory activity against Kv1.3. Several demonstrated simila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e446dcc67f45aee64239596e8f347acb
https://doi.org/10.1016/j.bmcl.2010.09.131
https://doi.org/10.1016/j.bmcl.2010.09.131
Publikováno v:
Expert Opinion on Drug Discovery. 2:1669-1681
The recombinant baculovirus/insect cell system was firmly established as a leading method for recombinant protein production when a new potential use for these viruses was revealed in 1995. It was reported that engineered recombinant baculoviruses co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba4c688c7ff04b13a5ffe703ecb39bb
https://doi.org/10.1517/17460441.2.12.1669
https://doi.org/10.1517/17460441.2.12.1669
Publikováno v:
Nature Biotechnology
Today, many thousands of recombinant proteins, ranging from cytosolic enzymes to membrane-bound proteins, have been successfully produced in baculovirus-infected insect cells. Yet, in addition to its value in producing recombinant proteins in insect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::620c53014dc94d8884ace7bd8b7d864d
https://doi.org/10.1038/nbt1095
https://doi.org/10.1038/nbt1095
Publikováno v:
Protein Expression and Purification. 38:17-23
The expression of recombinant proteins following transduction of CHO cells with recombinant baculoviruses containing a mammalian expression cassette with the CMV-promoter is enhanced by the addition of trichostatin A (TSA), a specific histone deacety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bcecc0d48eeace00977cc8dba2bce5b
https://doi.org/10.1016/j.pep.2004.08.001
https://doi.org/10.1016/j.pep.2004.08.001
Autor:
Katherine E. Kilpatrick, Janet H. Parham, Gregory Pahel, J. Patrick Condreay, Jeff T. Hutchins, Eric P. Dixon, Sandy A. Kerner
Publikováno v:
Hybridoma and Hybridomics. 21:237-243
Previously we demonstrated the rapid generation of affinity matured monoclonal antibody (MAb) producing cell lines following gene gun delivery of DNA using a mammalian expression vector (pAlpha/hFc), which enables the expression of human Fc-chimera p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7883583843acdf3cc4c1c1807468dbb
https://doi.org/10.1089/153685902760213840
https://doi.org/10.1089/153685902760213840
Autor:
Thomas A. Kost, J. Patrick Condreay
Publikováno v:
Trends in Biotechnology. 20:173-180
The baculovirus expression system has been used extensively for the expression of recombinant proteins in insect cells. Recently, recombinant baculovirus vectors engineered to contain mammalian cell-active promoter elements, have been used successful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15eb90ca19583c3bcec6251ac18b2791
https://doi.org/10.1016/s0167-7799(01)01911-4
https://doi.org/10.1016/s0167-7799(01)01911-4
Autor:
James F. Truax, J. Patrick Condreay, Jennings F. Worley, Christopher J. Apolito, T. A. Kost, Gang An, Jeffrey L. Pfohl
Publikováno v:
Receptors and Channels. 8:99-111
A variety of transfection approaches have been used to deliver plasmids encoding ion channel genes into cells. We have used the baculovirus transduction system, BacMam, to demonstrate transient expression of multi-subunit KATP channels in CHO-K1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14c6c702e77a5c196eef4afb362f061f
https://doi.org/10.3109/10606820212396
https://doi.org/10.3109/10606820212396
Autor:
Richard K. Gaillard, Eric P. Dixon, William C. Clay, Julie A. Barnes, J. Patrick Condreay, Jui-Lan Su, Derril H. Willard, Thomas A. Kost, Christine R. Hoffman, Laurie K. Overton, David C. Lobe, Greg L. Pahel, David J.T. Porter, Warren J. Rocque, William C. Phelps
Publikováno v:
Protein Expression and Purification. 18:148-159
Replication of human papillomavirus type11 (HPV11) requires both the E1 and the E2 proteins. E1 is structurally and functionally similar to SV40 large T-antigen and is a DNA helicase/NTPase that binds to the origin of replication and initiates viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c584eb9241d8e3f2b04cd68dd43cb81
https://doi.org/10.1006/prep.1999.1182
https://doi.org/10.1006/prep.1999.1182
Autor:
J. Patrick Condreay, Christian Watson
Publikováno v:
Current Protocols in Pharmacology
The development of cell-based assays for cellular receptors, ion channels, and transporters requires the delivery and expression of transgenes. Viral-mediated gene delivery is a particularly attractive approach for this purpose because of its efficie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4905acf9c8702f19b4815046f40cbd28
https://pubmed.ncbi.nlm.nih.gov/22294374
https://pubmed.ncbi.nlm.nih.gov/22294374