Zobrazeno 1 - 10
of 90
pro vyhledávání: '"J Pataricza"'
Publikováno v:
Life Sciences. 47:1941-1948
Earlier we demonstrated that micellar solutions of LPC caused endothelium-dependent relaxation of rabbit thoracic aorta and bovine intrapulmonary artery and vein through a cyclic GMP-dependent mechanism. The availability of LPC for vasorelaxation dep
Publikováno v:
Acta physiologica Hungarica. 91(3-4)
Functional role of calcium-activated potassium (KCa) channels on the basal and agonist-elevated arterial tones was investigated in isolated rabbit aorta, porcine and canine coronary arteries as well as in human internal mammary artery. The vascular t
Publikováno v:
Cardiovascular drugs and therapy. 14(6)
Publikováno v:
Acta physiologica Hungarica. 84(3)
Synthetic iberiotoxin (IBTX), an inhibitor of large conductance calcium-activated potassium channel (BKCa), was used to study the possible involvement of a specific hyperpolarizing ion channel in nitric oxide (NO)-induced venodilation. Serotonin (0.1
Publikováno v:
Basic research in cardiology. 86
Evidence is accumulating that acute stress situations such as ischemia, adrenergic dominance, and ouabain intoxication enhance production of endogenous substances (PgI2, adenosine, NO) which may protect the myocardium from harmful consequences of the
Autor:
J Pataricza
Publikováno v:
Journal of Molecular and Cellular Cardiology. 23:S93
Akademický článek
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Publikováno v:
Advances in myocardiology. 6
Therapeutic application of prostaglandin I2 (PGI2) is rendered difficult by its instability. The 7-oxo-derivative synthesized by Kovács et al. [8] proved to be stable in aqueous solution. Both drugs were tested in experimental model angina in anesth
Publikováno v:
Biomedica biochimica acta. 43(8-9)
Earlier we have shown in the dog model mimicking angina on effort a delayed antiischaemic effect of PgI2 and its stable analogue 7-oxo-PgI2-Na, appearing only when the drug induced marked vasodilatation was over [1]. In the present experiments we cou