Zobrazeno 1 - 10
of 121
pro vyhledávání: '"J Pablo Huidobro-Toro"'
Autor:
Fernando Valiente-Echeverría, Maricarmen Vallejos, Anne Monette, Karla Pino, Alejandro Letelier, J Pablo Huidobro-Toro, Andrew J Mouland, Marcelo López-Lastra
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56962 (2013)
Translation initiation from the human immunodeficiency virus type-1 (HIV-1) mRNA can occur through a cap or an IRES dependent mechanism. Cap-dependent translation initiation of the HIV-1 mRNA can be inhibited by the instability element (INS)-1, a cis
Externí odkaz:
https://doaj.org/article/554fc09d028f4c5a91f6531c82a0caac
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
The vesicular nucleotide transporter (VNUT) is critical for sympathetic co-transmission and purinergic transmission maintenance. To examine this proposal, we assessed whether the bisphosphonate clodronate, claimed as a potent in vitro VNUT blocker, m
Externí odkaz:
https://doaj.org/article/6c1ca1f1c1a749b6b7276874584f5242
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 16 (2021)
Background The vascular pharmacodynamics of anthocyanins is only partially understood. To examine whether the anthocyanin‐induced vasorelaxation is related to membrane estrogen receptor activity, the role of ERα or GPER antagonism was ascertained
Externí odkaz:
https://doaj.org/article/88a98d808e3b4905a7e7db3f8ee8c89c
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The vascular pharmacodynamics of anthocyanins is only partially understood. To examine whether the anthocyanin‐induced vasorelaxation is related to membrane estrogen receptor activity, the role of ERα or GPER antagonism was ascertained
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 18
International Journal of Molecular Sciences, Vol 21, Iss 6940, p 6940 (2020)
Volume 21
Issue 18
International Journal of Molecular Sciences, Vol 21, Iss 6940, p 6940 (2020)
P2 ×
4R is allosterically modulated by Zn(II), and despite the efforts to understand the mechanism, there is not a consensus proposal
C132 is a critical amino acid for the Zn(II) modulation, and this residue is located in the receptor
4R is allosterically modulated by Zn(II), and despite the efforts to understand the mechanism, there is not a consensus proposal
C132 is a critical amino acid for the Zn(II) modulation, and this residue is located in the receptor
Autor:
J. Pablo Huidobro-Toro, Felipe Hernández, M. Verónica Donoso, Claudio Acuña-Castillo, Tania Villalón
Publikováno v:
Purinergic Signalling. 14:121-139
Endothelial cells participate in extracellular ATP release elicited by mechanosensors. To characterize the dynamic interactions between mechanical and chemical factors that modulate ATP secretion by the endothelium, we assessed and compared the mecha
Autor:
J. Pablo Huidobro Toro
Publikováno v:
Ars Medica, Vol 12, Iss 2, Pp 39-47 (2017)
Sin resumen
Autor:
J Pablo Huidobro-Toro
Publikováno v:
Open access Journal of Neurology & Neurosurgery. 4
Publikováno v:
AUTONOMIC NEUROSCIENCE: BASIC & CLINICAL
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
The vas deferens is a simple bioassay widely used to study the physiology of sympathetic neurotransmission and the pharmacodynamics of adrenergic drugs. The role of ATP as a sympathetic co-transmitter has gained increasing attention and furthered our
Publikováno v:
revneuro. 22:335-354
Seven mammalian purinergic receptor subunits, denoted P2X1–P2X7, and several spliced forms of these subunits have been cloned. When heterologously expressed, these cDNAs encode ATP-gated non-selective cation channels organized as trimers. All activ