Zobrazeno 1 - 10
of 53
pro vyhledávání: '"J P Papin"'
Autor:
Monique Capron, Sébastien Fleury, Patrick Rémy, Georges Abboud, Nathalie Deruytter, J P Papin, Delphine Staumont-Sallé, Thomas Roumier, David Dombrowicz, Céline Lavogiez, Akira Kanda
Publikováno v:
The Journal of Immunology. 182:6517-6526
The high-affinity IgE receptor Fc(epsilon)RI and, in some models, the low-affinity IgG receptor Fc(epsilon)RIIII/CD16 play an essential role in allergic diseases. In human skin, they are present on APCs and effector cells recruited into the inflamed
Autor:
Kohei Honda, Johan Auwerx, Monique Capron, David Dombrowicz, Gaëtane Woerly, Marc Loyens, Bart Staels, J P Papin
Publikováno v:
The Journal of Experimental Medicine
Allergic asthma is characterized by airway hyperresponsiveness, eosinophilia, and mucus accumulation and is associated with increased IgE concentrations. We demonstrate here that peroxisome proliferator-activated receptors (PPARs), PPAR-alpha and PPA
Publikováno v:
The Journal of Immunology. 167:995-1003
FcεRI expressed by human eosinophils is involved in IgE-mediated cytotoxicity reactions toward the parasite Schistosoma mansoni in vitro. However, because receptor expression is low on these cells, its functional role is still controversial. In this
Publikováno v:
The Journal of Immunology. 165:1266-1271
Besides its crucial role in type I hypersensitivity reactions, IgE is involved in anti-parasite immunity. This role has been clearly demonstrated in both human and rat schistosomiasis, but remains controversial in the mouse. Since the cellular distri
Autor:
Justine Bertrand-Michel, Céline Brénuchon, François Tercé, Monique Capron, Akira Kanda, Sébastien Fleury, Thomas Roumier, Patrick Rémy, Céline Lavogiez, Bart Staels, David Dombrowicz, J P Papin, Delphine Staumont-Sallé, Emmanuel Delaporte, Georges Abboud
Publikováno v:
The Journal of allergy and clinical immunology. 121(4)
Background The peroxisome proliferator-activated receptors (PPARs) α, β/δ, and γ are ligand-activated transcription factors belonging to the nuclear receptor superfamily. In addition to their regulatory role on lipid and glucose metabolism, they
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 165(3)
Besides its crucial role in type I hypersensitivity reactions, IgE is involved in anti-parasite immunity. This role has been clearly demonstrated in both human and rat schistosomiasis, but remains controversial in the mouse. Since the cellular distri
Publikováno v:
European journal of immunology. 29(3)
Killing of Schistosoma mansoni larvae by human eosinophils via antibody-dependent cell-mediated cytotoxicity (ADCC) mechanisms requires adherence between effector cells and parasite targets. The role of adhesion molecules in this mechanism was invest
Publikováno v:
International archives of allergy and immunology. 116(2)
Recent reports describe the beneficial use of lodoxamide, an anti-allergic compound, for the treatment of asthma and allergic conjunctivitis. Lodoxamide is known as a mast cell stabilizer, however, the association of a significant clinical improvemen
Autor:
Sylvie Loiseau, J P Kusnierz, Marie-José Truong, J P Papin, Valérie Gruart, André Capron, Monique Capron
Publikováno v:
The Journal of Experimental Medicine
It has been suggested that neutrophils may be involved in the late-phase reaction of immunoglobulin E (IgE)-dependent hypersensitivity states. However, the identity of neutrophil-associated molecules inducing the release of mediators remains unclear.
Autor:
Nicolas Hornez, Fanny Legrand, J P Papin, Marwan Abdallah, Julie Bertout, Virginie Driss, Thomas Roumier, Severine Quéant, Patrick Rémy, Akira Kanda, Valérie Julia, Georges Abboud, David Dombrowicz, Delphine Staumont-Sallé, Monique Capron, Sébastien Fleury
Publikováno v:
Journal of Allergy and Clinical Immunology. 124:573-582.e9
Background Eosinophils are key players in T H 2-driven pathologies, such as allergic lung inflammation. After IL-5– and eotaxin-mediated tissue recruitment, they release several cytotoxic and inflammatory mediators. However, their exact contributio