Zobrazeno 1 - 10
of 59
pro vyhledávání: '"J P Mather"'
Effects of temperature shift on cell cycle, apoptosis and nucleotide pools in CHO cell batch cultues
Autor:
A, Moore, J, Mercer, G, Dutina, C J, Donahue, K D, Bauer, J P, Mather, T, Etcheverry, T, Ryll
Publikováno v:
Cytotechnology. 23(1-3)
Temperature reduction in CHO cell batch culture may be beneficial in the production of recombinant protein and in maintenance of viability. The effects on cell cycle, apoptosis and nucleotide pools were studied in cultures initiated at 37°C and temp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ea106d2099594f718fd0549ad404f31
https://pubmed.ncbi.nlm.nih.gov/22358520
https://pubmed.ncbi.nlm.nih.gov/22358520
Publikováno v:
Endocrinology. 134:1967-1970
Follistatin is an activin-binding glycoprotein that decreases FSH secretion in vitro and in vivo in rats. The mechanism by which follistatin acts is unclear, but it has been suggested that it may bind endogenous activin and neutralize its effects. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e455577505c87096ba8764bb1f93ba2f
https://doi.org/10.1210/endo.134.4.8137764
https://doi.org/10.1210/endo.134.4.8137764
Publikováno v:
Endocrinology. 141(9)
FSH plays a crucial role in granulosa cell differentiation and follicular development during the ovulation cycle. The early events of granulosa cell differentiation in cell culture involve changes in the cell morphology and cell-to-cell interactions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9bea4c4115fa8560d7b8c26dfad15e9c
https://pubmed.ncbi.nlm.nih.gov/10965919
https://pubmed.ncbi.nlm.nih.gov/10965919
Publikováno v:
Journal of andrology. 21(2)
Receptor tyrosine kinases act to convey extracellular signals to intracellular signaling pathways and ultimately control cell proliferation and differentiation. Rse, Axl, and Mer belong to a newly identified family of cell adhesion molecule-related r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24e0e38efef3cfc9e51eae663452dddf
https://pubmed.ncbi.nlm.nih.gov/10714824
https://pubmed.ncbi.nlm.nih.gov/10714824
Publikováno v:
Testis, Epididymis and Technologies in the Year 2000 ISBN: 9783662040522
The inception of genetic engineering, the complete sequencing of human, animal and plant genomes, and the information revolution in the last quarter of the 20th century will forever change the way in which biological and medical science is carried ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5550a21bac0c52662c0c74df359d452
https://doi.org/10.1007/978-3-662-04050-8_2
https://doi.org/10.1007/978-3-662-04050-8_2
Publikováno v:
Methods in cell biology. 57
Understanding the dynamics of cell death in conjunction with those of cell cycle can be illuminating in the investigation of various cellular behaviors. Robust assays for measuring such parameters are invaluable. Many assays of apoptosis and/or cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2512fb0e7fad0a45a716ddb21a1956a9
https://pubmed.ncbi.nlm.nih.gov/9648110
https://pubmed.ncbi.nlm.nih.gov/9648110
Autor:
J P, Mather
Publikováno v:
Methods in cell biology. 57
With the modern tools of molecular and cell biology now available, many researchers find the need to scale up cell culture in order to produce large quantities of cells or conditioned medium for the further purification of proteins or subcellular fra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41262e0e37a45b4f468f30119824239d
https://pubmed.ncbi.nlm.nih.gov/9648107
https://pubmed.ncbi.nlm.nih.gov/9648107
Autor:
J P, Mather
Publikováno v:
Methods in cell biology. 57
Complex nutrient mixtures, which are usually called "media," are almost always supplemented with serum, with another complex biological fluid (e.g., milk, embryo extracts, and plasma), or with a defined mixture of hormones and growth factors. The cho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::151f610a4b2b34f660183a5bc8d5cc75
https://pubmed.ncbi.nlm.nih.gov/9648097
https://pubmed.ncbi.nlm.nih.gov/9648097
Publikováno v:
Endocrinology. 138(11)
In addition to the regulation of FSH secretion, it has been clearly shown that inhibin and activin have paracrine/autocrine effects in the gonads. We have studied the effect of human recombinant inhibin A and human recombinant activin A on immature p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8fbde1ecbda3d31ed0002900db917972
https://pubmed.ncbi.nlm.nih.gov/9348206
https://pubmed.ncbi.nlm.nih.gov/9348206
Publikováno v:
Inhibin, Activin and Follistatin ISBN: 9781461273202
Inhibin and activin were first described as feedback inhibitors of pituitary function. However, a range of data now supports the hypothesis that these factors play a major role in the paracrine regulation of gonadal function (1, 2). Activin seems to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5639feae19c5377cfd9d8d0538e702d8
https://doi.org/10.1007/978-1-4612-1874-6_5
https://doi.org/10.1007/978-1-4612-1874-6_5