Zobrazeno 1 - 10
of 18
pro vyhledávání: '"J P Laurino"'
Publikováno v:
Clinical Chemistry. 42:1454-1459
We evaluated the clinical utility of the mass measurement of the tissue isoform of creatine kinase MB isoenzyme (CK-MB2) in the diagnosis of an acute myocardial infarction (AMI) by determining its sensitivity, specificity, and predictive value relati
Autor:
J P, Laurino
Publikováno v:
Annals of clinical and laboratory science. 30(4)
Cardiac troponin I (cTnI) is now widely recognized as one of the preeminent biochemical markers for the diagnosis of myocardial injury. The biochemical specificity of this biomolecule for cardiac tissue has forced a reevaluation of the diagnostic cri
Autor:
I S, Soares, J W, Barnwell, M U, Ferreira, M, Gomes Da Cunha, J P, Laurino, B A, Castilho, M M, Rodrigues
Publikováno v:
Molecular medicine (Cambridge, Mass.). 5(7)
BACKGROUND: The 19 kDa C-terminal region of the merozoite surface protein 1 (MSP1(19)) has been suggested as candidate for part of a subunit vaccine against malaria. A major concern in vaccine development is the polymorphism observed in different pla
Publikováno v:
Annals of clinical and laboratory science. 29(3)
The development of monoclonal antibody-based immunochemical assays to measure antibodies, antigens and small molecules, such as drugs, ushered in a revolution in modern diagnostic medicine. The impact of monoclonal antibodies on diagnostic imaging te
Publikováno v:
Annals of clinical and laboratory science. 27(5)
The major limitation of current diagnostic methods for the rapid diagnosis of an acute myocardial infarction (AMI) involves the measurement of the effects of ischemic or necrotic processes on myocardial function rather than the detection of the preci
Publikováno v:
Annals of clinical and laboratory science. 27(3)
Tourette's syndrome (TS) is a complex neurobehavioral disorder emerging in childhood and is characterized by motor and vocal tics of at least one year in duration. In a portion of patients with TS, environmental (non-genetic) factors may either have
Publikováno v:
The Journal of the American Board of Family Practice. 9(5)
We were interested in studying whether a family history of coronary heart disease (CHD) persisted as a significant risk factor for premature coronary heart disease after adjusting for traditional and nontraditional risk factors.Ninety-five case patie
Publikováno v:
Clinical chemistry. 42(9)
We evaluated the clinical utility of the mass measurement of the tissue isoform of creatine kinase MB isoenzyme (CK-MB2) in the diagnosis of an acute myocardial infarction (AMI) by determining its sensitivity, specificity, and predictive value relati
Autor:
A G, Bostom, A L, Hume, C B, Eaton, J P, Laurino, L R, Yanek, M S, Regan, W H, McQuade, W Y, Craig, G, Perrone, P F, Jacques
Publikováno v:
Pharmacotherapy. 15(4)
To determine the efficacy of high-dose ascorbate supplementation in lowering lipoprotein(a) [Lp(a)] levels in patients with premature coronary heart disease (CHD).Randomized, double-blind, placebo-controlled trial.Outpatient clinic.Forty-four patient
Publikováno v:
Annals of clinical and laboratory science. 25(3)
The isoforms of CK-MB have recently received attention as potential biochemical markers for the early diagnosis of an acute myocardial infarction. A sensitive (analytical sensitivity = 0.2 ng/ml) immunochemical mass assay for the direct measurement o