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pro vyhledávání: '"J P Lake"'
Autor:
F A Tobolowsky, N Wada, O Martinez-Maza, L Magpantay, S L Koletar, F J Palella, T T Brown, J E Lake
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191606 (2018)
IntroductionLymphoid tissue fibrosis may contribute to incomplete immune reconstitution on antiretroviral therapy (ART) via local CD4+ T lymphocyte (CD4) depletion. Hyaluronic acid (HA) increases with fibrotic burden. CXCL4 concentrations increase in
Externí odkaz:
https://doaj.org/article/eebc227b1b74489ca1faf42c5b9652af
Autor:
A. J. P. Lake
Publikováno v:
Anaesthesia. 56:1203-1216
Publikováno v:
The Journal of Immunology. 148:1620-1629
T cell maturation in an extrathymic environment has been studied using as a model the congenitally athymic nude mouse. Phenotypic analyses as a function of age were conducted on lymphocytes obtained from the spleens and lymph nodes of nude mice throu
Publikováno v:
The Journal of Immunology. 147:1121-1126
Phenotypic analysis of lymphocytes that mature extrathymically in congenitally athymic nude mice has revealed a large population of CD3+ CD8+ T cells that express gamma/delta-TCR. In euthymic mice, significant numbers of cells with this phenotype are
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 158(8)
Oral administration of Ag, over a period of several days, induces a state of tolerance that is associated with activation of CD8+ T cells that can transfer unresponsiveness to naive syngeneic hosts. We previously demonstrated that these T cells are n
Publikováno v:
The Journal of Immunology. 140:3296-3302
A Ts cell subset has been identified in the spleens of responder mice 3 to 6 wk after immunization with an optimally immunogenic dose of L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT). These Ts were positively selected by panning procedures by usin
Publikováno v:
The Journal of Immunology. 136:805-812
Athymic nude mice implanted with F1 thymus glands were used to investigate genetic restrictions regulating T cell-macrophage (M phi) interactions in the development of antibody responses to GAT. Spleen cells from conventional mice developed comparabl
Publikováno v:
The Journal of Experimental Medicine
The in vitro secondary cytotoxic T lymphocyte (CTL) response to Sendai virus-treated stimulator cells by primed spleen cells from thymus gland-grafted nude mice was examined. BALB/c (H-2d) nude mice grafted with allogeneic C57BL/10 (H-2b) thymus glan
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 136(4)
The roles of helper and suppressor T cells in the development and expression of antibody responses to GAT were studied in (responder X responder)F1 mice immunized with parental GAT-M phi. Spleen cells from (B10 X B10.D2)F1 mice primed in vivo with B1
Autor:
D D, Isaak, J P, Lake
Publikováno v:
Thymus. 4(5)
In contrast to lymph node cells from nonthymus gland-implanted nude mice, which failed to respond to foreign alloantigens in mixed lymphocyte reaction tests, lymph node cells from nude mice implanted with either syngeneic or allogeneic thymuses respo