Zobrazeno 1 - 10
of 34
pro vyhledávání: '"J P Hinson"'
Autor:
Feria A. Ladha, Ketan Thakar, Anthony M. Pettinato, Nicholas Legere, Shahnaz Ghahremani, Rachel Cohn, Robert Romano, Emily Meredith, Yu-Sheng Chen, J. Travis Hinson
Publikováno v:
Cell Reports, Vol 36, Iss 6, Pp 109512- (2021)
Summary: Actinins are strain-sensing actin cross-linkers that are ubiquitously expressed and harbor mutations in human diseases. We utilize CRISPR, pluripotent stem cells, and BioID to study actinin interactomes in human cardiomyocytes. We identify 3
Externí odkaz:
https://doaj.org/article/e6307fe6bca2447b9447356fa2b7a8c9
Autor:
Rachel Cohn, Ketan Thakar, Andre Lowe, Feria A. Ladha, Anthony M. Pettinato, Robert Romano, Emily Meredith, Yu-Sheng Chen, Katherine Atamanuk, Bryan D. Huey, J. Travis Hinson
Publikováno v:
Stem Cell Reports, Vol 12, Iss 1, Pp 71-83 (2019)
Summary: Thick-filament sarcomere mutations are a common cause of hypertrophic cardiomyopathy (HCM), a disorder of heart muscle thickening associated with sudden cardiac death and heart failure, with unclear mechanisms. We engineered four isogenic in
Externí odkaz:
https://doaj.org/article/5859d4a741e64ad684d268f581623897
Autor:
Anthony M. Pettinato, Dasom Yoo, Jennifer VanOudenhove, Yu-Sheng Chen, Rachel Cohn, Feria A. Ladha, Xiulan Yang, Ketan Thakar, Robert Romano, Nicolas Legere, Emily Meredith, Paul Robson, Michael Regnier, Justin L. Cotney, Charles E. Murry, J. Travis Hinson
Publikováno v:
Cell Reports, Vol 35, Iss 5, Pp 109088- (2021)
Summary: Human cardiac regeneration is limited by low cardiomyocyte replicative rates and progressive polyploidization by unclear mechanisms. To study this process, we engineer a human cardiomyocyte model to track replication and polyploidization usi
Externí odkaz:
https://doaj.org/article/847db9f1ea284d26af489605c9dc05dc
Autor:
J. Travis Hinson, Anant Chopra, Andre Lowe, Calvin C. Sheng, Rajat M. Gupta, Rajarajan Kuppusamy, John O'Sullivan, Glenn Rowe, Hiroko Wakimoto, Joshua Gorham, Kehan Zhang, Kiran Musunuru, Robert E. Gerszten, Sean M. Wu, Christopher S. Chen, Jonathan G. Seidman, Christine E. Seidman
Publikováno v:
Cell Reports, Vol 17, Iss 12, Pp 3292-3304 (2016)
AMP-activated protein kinase (AMPK) is a metabolic enzyme that can be activated by nutrient stress or genetic mutations. Missense mutations in the regulatory subunit, PRKAG2, activate AMPK and cause left ventricular hypertrophy, glycogen accumulation
Externí odkaz:
https://doaj.org/article/8a8d917c3fe94409bb77320752abdbde
Autor:
J. Travis Hinson, Anant Chopra, Andre Lowe, Calvin C. Sheng, Rajat M. Gupta, Rajarajan Kuppusamy, John O’Sullivan, Glenn Rowe, Hiroko Wakimoto, Joshua Gorham, Michael A. Burke, Kehan Zhang, Kiran Musunuru, Robert E. Gerszten, Sean M. Wu, Christopher S. Chen, Jonathan G. Seidman, Christine E. Seidman
Publikováno v:
Cell Reports, Vol 19, Iss 11, p 2410 (2017)
Externí odkaz:
https://doaj.org/article/a55d9725f02a4a78971d08e8db75c07c
Autor:
P W Raven, J P Hinson
Publikováno v:
Menopause International. 13:75-78
Since we last reviewed this topic in 2001, considerably more information about dehydroepiandrosterone (DHEA) has accrued, but this has not necessarily left us any wiser about the use of this steroid in postmenopausal women. There is no further eviden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe359abbd6b0ff17fdc17375c1fc5c6d
https://doi.org/10.1258/175404507780796370
https://doi.org/10.1258/175404507780796370
Autor:
J. P. Hinson
Publikováno v:
Endocrine Reviews. 21:138-167
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ce3aa12298a371cff3663f68fd85e40
https://doi.org/10.1210/er.21.2.138
https://doi.org/10.1210/er.21.2.138
Autor:
J P Hinson, S Kapas
Publikováno v:
Hormone and Metabolic Research. 30:334-340
There is evidence to suggest that the cells of the vascular endothelium secrete factors, including endothelin-1, nitric oxide, adrenomedullin and PAMP which have a role in regulating adrenal function. There is strong evidence from many studies that e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae37e32dbabadca436c6738790dbb53
https://doi.org/10.1055/s-2007-978894
https://doi.org/10.1055/s-2007-978894
Autor:
J. P. Hinson, S. Kapas
Publikováno v:
Endocrine Research. 22:861-865
The actions of adrenomedullin on cAMP and aldosterone secretion have been investigated using an intact rat adrenal capsular preparation incubated in vitro. Adrenomedullin was found to cause a dose-dependent increase in aldosterone secretion, with a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff5d9a4cffe6ca29fe6a3b76149c08ba
https://doi.org/10.1080/07435809609043787
https://doi.org/10.1080/07435809609043787
Publikováno v:
Endocrinology. 137:3291-3294
The cloned mouse ACTH receptor was expressed in stably transfected human HeLa cells that lack an endogenous melanocortin receptor. ACTH[1-39] and several N- and C-terminally truncated analogues of ACTH were studied for their ability to stimulate cAMP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299280b926d620bb3db097830db8b6fa
https://doi.org/10.1210/endo.137.8.8754753
https://doi.org/10.1210/endo.137.8.8754753