Elastin-like polypeptide coacervates as reversibly triggerable compartments for synthetic cells

Autor: Chang Chen, Ketan A. Ganar, Robbert J. de Haas, Nele Jarnot, Erwin Hogeveen, Renko de Vries, Siddharth Deshpande

Publikováno v: Communications Chemistry, Vol 7, Iss 1, Pp 1-11 (2024)

Abstract Compartmentalization is a vital aspect of living cells to orchestrate intracellular processes. In a similar vein, constructing dynamic and responsive sub-compartments is key to synthetic cell engineering. In recent years, liquid-liquid phase

Externí odkaz: https://doaj.org/article/30807c6d68a8445baed61cfd79299700

Optimised treatment of patients with enlarged lateral lymph nodes in rectal cancer: protocol of an international, multicentre, prospective registration study after extensive multidisciplinary training (LaNoReC)

Autor: Susan Van Dieren, Joost Nederend, Pieter J Tanis, Roel Hompes, Klaas Havenga, Melissa W Taggart, Robert Riedl, Michail Doukas, Evert-Jan G. Boerma, Marinke Westerterp, Corrie A M Marijnen, Jaap Stoker, Andrew Ruszkiewicz, Tsuyoshi Konishi, Jarno Melenhorst, Karin Muller, Krista Gerbrands, Michael Croft, Michael Wilks, Johanne G. Bloemen, Peter A. Neijenhuis, Koen C.M.J. Peeters, Miranda Kusters, Martijn Intven, Jan Peringa, Maria Verseveld, Eline G M van Geffen, Tania C Sluckin, Sanne-Marije J A Hazen, Karin Horsthuis, Geerard Beets, Marilyne M Lange, Regina G H Beets-Tan, Marc R. W. Engelbrecht, Elisabeth D. Geijsen, Philip Meijnen, Jurriaan B. Tuynman, Ingrid M. Bruijnzeel, Bas Lamme, Femke M. Alberts, Rogier M. P. H. Crolla, Joanne Verdult, Johan H. Wijsman, Charlotte S. van Kessel, Erik Jan Mulder, Jan Binne Hulshoff, Ivan M. Cherepanin, Hans F. J. Fabry, G. Y. Mireille, Frank J. M. Kemper, Fatih Polat, Jacobus W. A. Burger, Jeltsje S. Cnossen, Shira H. de Bie, Robbert J. I. Bosker, Aaldert K. Talsma, Leonora S. F. Boogerd, Marc J. P. M. Govaert, Merel M. Scheurkogel, Imogeen E. Antonisse, Joost Rothbarth, Marianne de Vries, Marcel A. H. Ribbert, Anthony W. H. van de Ven, Susan ter Borg, Jennifer W. Bradshaw, Heleen M. Ceha, Fleur I. de Korte, Andreas W. K. S. Marinelli, Tjeerd S. Aukema, Liselotte W. van Bockel, Aukje A. J. M. van Tilborg, Tom Rozema, Amarins Brandsma, Stefan Hoogendoorn, Saskia R. Offerman, Hanneke Vos, Henderik L. van Westreenen, Jeroen W. A. Leijtens, Fabian A. Holman, Laura A. Velema, L Els, van Persijn van Meerten, Frans C. H. Bakers, Iryna Samarska, Nina Šefčovičová, Maaike Berbée, Bastiaan B. Pultrum, Dennis B. Rouw, Matthew Albert, L. René Arensman, Hanneke Basart, Esther C. J. Consten, Bart C.T. van de Laar, Inne Somers, Paul M. Verheijen, Thomas A. Fassaert, Christiaan Hoff, Eino B. van Duyn, Ellen M. Hendriksen, Hugo A.J. Gielkens, Arend G. J. Aalbers, Brechtje A. Grotenhuis, Michalda S. Dunker, Anne M. van Geel, Christof Meischl, W. Hermien Schreurs, Patty H. Spruit, Michael F. Gerhards, Thomas M. Karsten, Eveline J.T. Krul, Sebastiaan van Koeverden, Andre J. A. Bremers, Heidi Rütten, Johannes H. W. de Wilt, Mariska den Hartogh, Vera Oppedijk, Jan Willem T. Dekker, Debora Eschbach-Zandbergen, Daphne Roos, Arjan van Tilburg, Ernst Jan, Spillenaar Bilgen, Nikki Knijn, Marnix A. J. de Roos, Ilse van Dop, Tracy Fitzsimmons, Hidde M. Kroon, Michael Penniment, Mitchell Raeside, Tarik Sammour, Steven J. Oosterling, Jeroen A. W. Tielbeek, Ronald J. C. L. M. Vuylsteke, Erik J. R. J. van der Hoeven, Anke B. Smits, Anniek H. Boer, Edgar J. B. Furnée, Robbert J. de Haas, Manon N. G. J. A. Braat, Wilhelmina M. U. van Grevenstein, Milan C. Richir, Patricia J. A. M. Brouwers, Tilly Leseman, Eric H. J. Belgers, Jasenko Krdzalic, Roy F. A. Vliegen

Publikováno v: BMJ Open, Vol 14, Iss 10 (2024)

Introduction Inadequate treatment of enlarged lateral lymph nodes (LLNs) in rectal cancer patients is associated with an increased lateral local recurrence (LLR) risk, despite neoadjuvant treatment and total mesorectal excision (TME) surgery. There i

Externí odkaz: https://doaj.org/article/340de40a283a4148be1229eb0c6c7cba

A dual-tracer approach using [11C]CH and [18F]FDG in HCC clinical decision making

Autor: Emile B. Veenstra, Simeon J. S. Ruiter, Robbert J. de Haas, Koert P. de Jong, Paola A. Erba, Rudi A. J. O. Dierckx, Walter Noordzij

Publikováno v: EJNMMI Research, Vol 13, Iss 1, Pp 1-9 (2023)

Abstract Background Early detection of recurrent or progressive HCC remains the strongest prognostic factor for survival. Dual tracer PET/CT imaging with [11C]CH and [18F]FDG can further increase detection rates as both tracers entail different metab

Externí odkaz: https://doaj.org/article/ad071cf27ddb46fcb8bd3e3ee94a7ac1

Post-treatment three-dimensional voxel-based dosimetry after Yttrium-90 resin microsphere radioembolization in HCC

Autor: Emile B. Veenstra, Simeon J. S. Ruiter, Robbert J. de Haas, Reinoud P. H. Bokkers, Koert P. de Jong, Walter Noordzij

Publikováno v: EJNMMI Research, Vol 12, Iss 1, Pp 1-9 (2022)

Abstract Background Post-therapy [90Y] PET/CT-based dosimetry is currently recommended to validate treatment planning as [99mTc] MAA SPECT/CT is often a poor predictor of subsequent actual [90Y] absorbed dose. Treatment planning software became avail

Externí odkaz: https://doaj.org/article/96b2919e78fd4b24b01ad67d763f94a2

Protocol for a randomized controlled multicenter trial assessing the efficacy of leuprorelin for severe polycystic liver disease: the AGAINST-PLD study

Autor: S. E. Aapkes, L. H. P. Bernts, A. P. van den Berg, M. van den Berg, H. Blokzijl, A. E. P. Cantineau, M. D. A. van Gastel, R. J. de Haas, P. Kappert, R. U. Müller, F. Nevens, R. Torra, A. Visser, J. P. H. Drenth, R. T. Gansevoort

Publikováno v: BMC Gastroenterology, Vol 22, Iss 1, Pp 1-11 (2022)

Abstract Background In patients with severe polycystic liver disease (PLD), there is a need for new treatments. Estrogens and possibly other female sex hormones stimulate growth in PLD. In some patients, liver volume decreases after menopause. Female

Externí odkaz: https://doaj.org/article/249419e1e30e46f0b6d00e3d79909557