Zobrazeno 1 - 8
of 8
pro vyhledávání: '"J P Groten"'
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 5, Pp 950-961 (1996)
Polychlorinated biphenyls (PCBs) dissolved in dietary fat are absorbed in the gastrointestinal tract by the enterocytes in combination with the fatty acids proceeding from the lipid hydrolysis in the gut lumen. The effect of fatty acid absorption on
Externí odkaz:
https://doaj.org/article/09f9d164db504915ab2c41f60bb9add8
Autor:
Victor J. Feron, J. P. Groten
Publikováno v:
Food and Chemical Toxicology. 40:825-839
This paper addresses major developments in the safety evaluation of chemical mixtures during the past 15 years, reviews today's state of the art of mixture toxicology, and discusses challenges ahead. Well-thought-out tailor-made mechanistic and empir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a8c28b2bdc23e0f62090fa19ad4c6e
https://doi.org/10.1016/s0278-6915(02)00021-2
https://doi.org/10.1016/s0278-6915(02)00021-2
Autor:
J. P. Groten, Victor J. Feron
Publikováno v:
ChemInform. 33
This paper addresses major developments in the safety evaluation of chemical mixtures during the past 15 years, reviews today's state of the art of mixture toxicology, and discusses challenges ahead. Well-thought-out tailor-made mechanistic and empir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4fb659d51229d429d2c62902a477818
https://doi.org/10.1002/chin.200242300
https://doi.org/10.1002/chin.200242300
Autor:
C, Meijer, A, Timmer, E G, De Vries, J P, Groten, A, Knol, N, Zwart, W A, Dam, D T, Sleijfer, N H, Mulder
Publikováno v:
International journal of cancer. 85(6)
Cisplatin (CDDP) is an extremely active drug in the treatment of germ-cell tumours. Earlier, we found an unexpected inverse correlation between the total amount of sulfhydryl groups and CDDP sensitivity in a panel of 3 human germ-cell-tumour and 3 co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41e324ad8686a48feb7c9b27d74d4c4e
https://pubmed.ncbi.nlm.nih.gov/10709094
https://pubmed.ncbi.nlm.nih.gov/10709094
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 287(1)
Palmitoyl carnitine chloride (PCC) has been shown to be an effective enhancer of intestinal transport of hydrophilic molecules. The exact mechanism by which the epithelial barrier function is decreased is not clear. In an attempt to elucidate the mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::877e701f7ceb8df8370e7b3011bf7d27
https://pubmed.ncbi.nlm.nih.gov/9765361
https://pubmed.ncbi.nlm.nih.gov/9765361
Publikováno v:
Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement. 20
A complex chemical mixture is defined as a mixture that consists of tens, hundreds or thousands of chemicals, and of which the composition is qualitatively and quantitatively not fully known. In contrast, a simple mixture consists of a relatively sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91b1a9285e4bdcd4edfa55867924f568
https://pubmed.ncbi.nlm.nih.gov/9442308
https://pubmed.ncbi.nlm.nih.gov/9442308
Autor:
J P, Groten
Publikováno v:
Nederlands tijdschrift voor tandheelkunde. 100(8)
Chronic exposure to mercury may lead to damage of the central nervous system and the kidneys. The first signs of neurotoxicity are difficult to recognize because the effects are very unspecific and show a high inter-individual variation. Patient and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::88d3036a61bcb2fabb869eae5192c347
https://pubmed.ncbi.nlm.nih.gov/11822123
https://pubmed.ncbi.nlm.nih.gov/11822123
Publikováno v:
IARC scientific publications. (118)
Part of the exogenous metallothionein present, e.g., in food of animal origin, can survive gastrointestinal digestion, and will be selectively taken up in the kidneys. The present paper describes a possible method of distinguishing exogenous cadmium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bb3ee5ee946b5fcd49e0b01941eff2ff
https://pubmed.ncbi.nlm.nih.gov/1303944
https://pubmed.ncbi.nlm.nih.gov/1303944