Zobrazeno 1 - 10
of 12
pro vyhledávání: '"J P Glover"'
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 16:167-172
The purpose of this study was to determine whether capillary dilation is one of the earliest structural changes in the diabetic-like retinopathy of the galactose-fed rat model and thus may represent a stage where intervention treatment might still be
Publikováno v:
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 16(2)
It has been proposed that oxidative tissue damage is involved in the development of diabetic angiopathies. To evaluate this hypothesis, experiments were conducted to identify the retinal vessel changes induced by the oxidative stress related to alpha
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 105:50-51
Publikováno v:
Investigative ophthalmologyvisual science. 39(10)
To determine whether the diabetic-like thickening of retinal capillary basement membrane (RCBM) that develops in the galactose-fed rat model of diabetic ocular complications could be halted or ameliorated after 4 or 8 months of galactosemia by treatm
Publikováno v:
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 14(2)
This study investigated whether diabetic-like corneal sensory deficits occur in the galactose-fed rat model of diabetic ocular complications and if such deficits could be prevented using either of two structurally different aldose reductase (AR) inhi
Publikováno v:
Journal of anatomy. 191
Computerised morphometry and a double stain technique were utilised to examine the corneal nerves in whole mounts. This novel stain combines the nonspecific acetylcholinesterase (NsAchE) and gold chloride (AuCl) procedures to enhance staining contras
Publikováno v:
Investigative ophthalmologyvisual science. 38(6)
To determine whether the diabeticlike retinal microangiopathies of the galactose-fed rat model could be ameliorated if intervention by withdrawal of the galactose diet or treatment with the aldose reductase inhibitor AL-3152 was initiated after quant
Publikováno v:
Investigative ophthalmologyvisual science. 37(6)
To evaluate the efficacy of WAY-121,509, a potent new aldose reductase inhibitor (ARI), in preventing the retinopathy that develops in the galactose-fed rat model of diabetic ocular complications.Sprague-Dawley rats were randomized into treatment and
Publikováno v:
Journal of anatomy. 188
The purpose of the present study was to determine if prolonged systemic arterial administration of basic fibroblast growth factor (bFGF) at a dose sufficient to enhance collateral vessel formation in the ischaemic hearts of dogs would produce retinal
Publikováno v:
Investigative ophthalmologyvisual science. 36(12)
To determine if the retinal microangiopathies of the galactose-fed rat model of diabetic retinopathy can be prevented with the aldose reductase inhibitor sorbinil.Sprague-Dawley rats were fed 50% d-galactose with or without sorbinil (0.05% wt/wt), mi