Zobrazeno 1 - 10
of 14
pro vyhledávání: '"J P Cogswell"'
Autor:
G Chandra, J P Cogswell, L R Miller, M M Godlevski, S W Stinnett, S L Noel, S H Kadwell, T A Kost, J G Gray
Publikováno v:
The Journal of Immunology. 155:4535-4543
An intact cAMP response element (CRE) in the upstream regulatory sequence of IL-1 beta (-2755/-2762) has been shown to be essential for maintaining full IL-1 beta inducibility following treatment with LPS, PMA, or TNF-alpha. In the present study, usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7edbe2367764fd5ef761ed52b936b9f
https://doi.org/10.4049/jimmunol.155.10.4535
https://doi.org/10.4049/jimmunol.155.10.4535
Publikováno v:
The Journal of Immunology. 153:712-723
In these studies, we show that NF-kappa B induces transcription from the human pro-IL-1 beta (IL-1 beta) gene. A recombinant plasmid pIL-1(-4000)-CAT, containing 4 kb of the IL-1 beta gene upstream regulatory sequence was transactivated by the p65 su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bee2b2842e0b1aeb453f63b809aa0af6
https://doi.org/10.4049/jimmunol.153.2.712
https://doi.org/10.4049/jimmunol.153.2.712
Publikováno v:
The Journal of Immunology. 146:1361-1367
The W and P elements are cis-acting transcriptional regulators of the human class II MHC gene HLA-DRA necessary for maximal promoter activity in DR+ B cells. Proteins that bind specifically to W may mediate promoter activity from a DNA segment contai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34cc6cdeb46fd13f6d526d35fa2442f9
https://doi.org/10.4049/jimmunol.146.4.1361
https://doi.org/10.4049/jimmunol.146.4.1361
Autor:
Diane M. Otterness, Randy T. McConnell, L.H. Zalkow, H. L. Carter, Wenge Xie, Robert T. Abraham, H. Peng, Garth Powis, J. P. Cogswell
Publikováno v:
Journal of medicinal chemistry. 44(5)
Silica gel supported pyrolysis of an azido-homo-oxa steroid led to rearrangement, presumably by a mechanism similar to that of solution phase Schmidt fragmentation, to produce a group of novel inhibitors for the oncogenic cell cycle regulator Cdc25A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b4ada2db8a21785459fc07e29e2f60d
https://pubmed.ncbi.nlm.nih.gov/11262093
https://pubmed.ncbi.nlm.nih.gov/11262093
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 11(12)
Polo-like kinase 1 (PLK1), which has been shown to have a critical role in mitosis, is one possible target for cancer therapeutic intervention. PLK1, at least in Xenopus, starts the mitotic cascade by phosphorylating and activating cdc25C phosphatase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2d7e6af6efe58b792fc0c8b7f8da9266
https://pubmed.ncbi.nlm.nih.gov/11149596
https://pubmed.ncbi.nlm.nih.gov/11149596
Autor:
K S, Katula, K L, Wright, H, Paul, D R, Surman, F J, Nuckolls, J W, Smith, J P, Ting, J, Yates, J P, Cogswell
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 8(7)
Control of cell proliferation is dependent on the regulated expression of the cyclin genes. Induction of cyclin B1 gene expression in S phase has been shown to require sequences within the first 90 bp of the proximal promoter region. In this study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b2a2c560891f6f3fdcc17f247c163009
https://pubmed.ncbi.nlm.nih.gov/9218875
https://pubmed.ncbi.nlm.nih.gov/9218875
Autor:
G, Chandra, J P, Cogswell, L R, Miller, M M, Godlevski, S W, Stinnett, S L, Noel, S H, Kadwell, T A, Kost, J G, Gray
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(10)
An intact cAMP response element (CRE) in the upstream regulatory sequence of IL-1 beta (-2755/-2762) has been shown to be essential for maintaining full IL-1 beta inducibility following treatment with LPS, PMA, or TNF-alpha. In the present study, usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ffd0670b5b2f3f9267bd1bedfa01cb2
https://pubmed.ncbi.nlm.nih.gov/7594450
https://pubmed.ncbi.nlm.nih.gov/7594450
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 153(2)
In these studies, we show that NF-kappa B induces transcription from the human pro-IL-1 beta (IL-1 beta) gene. A recombinant plasmid pIL-1(-4000)-CAT, containing 4 kb of the IL-1 beta gene upstream regulatory sequence was transactivated by the p65 su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b449ed46f0d004b3da549b6e628a756d
https://pubmed.ncbi.nlm.nih.gov/8021507
https://pubmed.ncbi.nlm.nih.gov/8021507
Publikováno v:
Critical reviews in immunology. 11(2)
Class II Major Histocompatibility Complex (MHC) products are essential initiators of cellular immune responses. Their cell surface expression demonstrates aspects of tissue-restricted, inducible, differentiation-dependent, and coordinate regulation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bbb77f7d89cf293365112d93af9286f9
https://pubmed.ncbi.nlm.nih.gov/1930684
https://pubmed.ncbi.nlm.nih.gov/1930684
Publikováno v:
The Journal of Immunology. 146:3260-3261
The W and P elements are cis-acting transcriptional regulators of the human class II MHC gene HLA-DRA necessary for maximal promoter activity in DR+ B cells. Proteins that bind specifically to W may mediate promoter activity from a DNA segment contai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90209e1f33cff6286fce10767fe8670a
https://doi.org/10.4049/jimmunol.146.9.3260.b
https://doi.org/10.4049/jimmunol.146.9.3260.b