Induction of Cure in Early Arthritis (I CEA): study protocol for an investigator-initiated randomized single-blind clinical trial with open-label extension to compare three treatment strategies in patients with newly diagnosed undifferentiated arthritis

Autor: S. A. Bergstra, L. van Ouwerkerk, I. S. Nevins, J. A. van der Pol, G. S. Helmich, I. Hest, A. van Veen, R. Bos, Y. P. M. Goekoop-Ruiterman, H. E. Vonkeman, J. Bijsterbosch, P. H. P. de Jong, M. Güler-Yüksel, S. Böhringer, T. W. J. Huizinga, F. A. van Gaalen

Publikováno v: Trials, Vol 25, Iss 1, Pp 1-15 (2024)

Abstract Background Undifferentiated arthritis (UA) is a term used to describe patients with inflammatory arthritis that has not differentiated into a specific rheumatic disease. UA may be a pre-stage of rheumatoid arthritis (RA) or another inflammat

Externí odkaz: https://doaj.org/article/f87499fd47d949ffb7a08bf248230bbf

Coronal approach for rehabilitative orbital decompression in Graves'ophthalmology

Autor: Leo Koornneef, Maarten P. Mourits, R. Kalmann, J. P. Van Der Pol

Publikováno v: British journal of ophthalmology, 81, 41-45. BMJ Publishing Group
British journal of ophthalmology, 81(1), 41-45. BMJ Publishing Group

AIMS—To determine the effectiveness and safety of three wall orbital decompression by the coronal approach in Graves' ophthalmopathy. METHODS—The records of 125 patients with Graves' ophthalmopathy, who had undergone three wall orbital decompress

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bece6f121f6b548c9077084384be37f4
https://doi.org/10.1136/bjo.81.1.41

Multidrug resistance-related proteins in primary choroidal melanomas and in vitro cell lines

Autor: J P, van der Pol, D J, Blom, M J, Flens, G P, Luyten, I, de Waard-Siebinga, L, Koornneef, R J, Scheper, M J, Jager

Publikováno v: Investigative ophthalmologyvisual science. 38(12)

Metastatic uveal melanoma is strongly resistant to chemotherapy, and multidrug resistance (MDR) may be involved. To investigate the role of MDR, the presence of the MDR-associated proteins P-glycoprotein (Pgp), MRP, and lung resistance protein (LRP)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5445ee2c156c10edb2f8d26d4354ec9c
https://pubmed.ncbi.nlm.nih.gov/9375571

Radioimmunoscintigraphy and immunohistochemistry with melanoma-associated monoclonal antibodies in choroidal melanoma: a comparison of the clinical and immunohistochemical results

Autor: M. J. P. G. Van Kroonenburgh, J. P. Van Der Pol, J. A. Oosterhuis, D. F. Schaling, Martine J. Jager, D. J. Ruiter

Publikováno v: The British journal of ophthalmology. 74(9)

Radioimmunoscintigraphy with monoclonal antibodies (MoAbs) to melanoma associated antigens is a new technique that can be used as an additional test to detect ocular melanomas in clinically difficult cases. Immunoscintigraphy with 99mtechnetium-label

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58f24b3fc4b0e8f41816e5c878f72d9
https://pubmed.ncbi.nlm.nih.gov/2203468

Heterogeneous expression of melanoma-associated antigens in uveal melanomas

Autor: P. J. Ringens, Martine J. Jager, J. P. van der Pol, D. De Wolff-Rouendaal, C. Vennegoor, D. J. Ruiter

Publikováno v: Current eye research. 6(6)

Twenty-five uveal melanomas were stained with seven monoclonal antibodies (MoAbs) recognizing different antigens on cutaneous melanomas. A two step immuno-peroxidase procedure was used. Phenotypic heterogeneity was observed for four MoAbs (M.2.2.4, A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8161ad4a1be978ae5218e81c6058ec46
https://pubmed.ncbi.nlm.nih.gov/3608565