Zobrazeno 1 - 10 of 18 pro vyhledávání: '"J P, Yevich"'
2
ChemInform Abstract: Second Generation Antimigraine 5-Ht1B/D Agonists: Structure-Activity Relationship and Preclinical Pharmacological Distinctions
Autor: Frank D. Yocca, J. P. Yevich
Publikováno v: ChemInform. 29
The discovery and development of the 5-HT 1b/D agonist sumatriptan for alleviating migraine pain has been an important advance in the field of modern headache treatment and research. This important therapeutic advance is not without it's shortcomings
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d3b06b31b125012f26c187a8d2b429a2
https://doi.org/10.1002/chin.199804260
Zobrazit plný text záznamu
4
Atypical antipsychotic agents: patterns of activity in a series of 3-substituted 2-pyridinyl-1-piperazine derivatives
Autor: Davis L. Temple, J. P. Yevich, D. P. Taylor, Leslie A. Riblet, S. M. Gross, Schlemmer Rf, K. B. New, Michael S. Eison, J. S. New
Publikováno v: Journal of Medicinal Chemistry. 31:618-624
A series of 3-substituted 2-pyridinyl-1-piperazine derivatives have been appended to cyclic imide groups and evaluated for their potential antipsychotic activity. The dopamine receptor affinities of these target molecules, as well as their ability to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc708f7a46c83e43bf6e2d3a08021d81
https://doi.org/10.1021/jm00398a021
Zobrazit plný text záznamu
7
The thieno[3,2-c]pyridine and furo[3,2-c]pyridine rings: new pharmacophores with potential antipsychotic activity
Autor: J. S. New, J. A. Cipollina, R. Butler, J. P. Yevich, Schlemmer Rf, W. L. Christopher, Cam P. VanderMaelen
Publikováno v: Journal of medicinal chemistry. 32(6)
Two new arylpiperazine derivatives, the 4-(1-piperazinyl)thieno- and -furo[3,2-c]pyridine ring systems, have been synthesized and appended via tetramethylene chains to various imide rings. Target compounds from each series were found to have signific
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74cd1c220afa99d671a7ad868b0022ca
https://pubmed.ncbi.nlm.nih.gov/2542551
Zobrazit plný text záznamu
10
Buspirone analogues. 1. Structure-activity relationships in a series of N-aryl- and heteroarylpiperazine derivatives
Autor: D. P. Taylor, J. S. New, J. P. Yevich, Leslie A. Riblet, Davis L. Temple
Publikováno v: Journal of medicinal chemistry. 26(2)
A series of analogues of buspirone was synthesized in which modifications were made in the aryl moiety, alkylene chain length, and cyclic imide portion of the molecule. These compounds were tested in vitro for their binding affinities to rat brain me
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d944d550f11653a9bd91bbc632376c3
https://pubmed.ncbi.nlm.nih.gov/6131130
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje