Zobrazeno 1 - 10
of 20
pro vyhledávání: '"J P, Wiebe"'
Autor:
Nicholas J P Wiebe, Irmtraud M Meyer
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 6, p e1000823 (2010)
The prediction of functional RNA structures has attracted increased interest, as it allows us to study the potential functional roles of many genes. RNA structure prediction methods, however, assume that there is a unique functional RNA structure and
Externí odkaz:
https://doaj.org/article/1d75e1d03c0541c78c0cc71a05460602
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 97(3)
Previous studies have shown that the progesterone metabolite, 5alpha-pregnane-3,20-dione (5alphaP), exhibits mitogenic and metastatic activity in breast cell lines and that specific, high affinity receptors for 5alphaP are located in the plasma membr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3de775394eb928a12de57d67318108cd
https://pubmed.ncbi.nlm.nih.gov/16154741
https://pubmed.ncbi.nlm.nih.gov/16154741
Publikováno v:
Journal of andrology. 21(5)
Intratesticular injections of glycerol have been shown to result in a marked and prolonged reduction of spermatogenesis, accompanied by increased permeability of the blood-testis barrier. Because the permeability of the blood-testis barrier is regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0c66067e6d15305590ce57adac8947c
https://pubmed.ncbi.nlm.nih.gov/10975408
https://pubmed.ncbi.nlm.nih.gov/10975408
Publikováno v:
Cancer research. 60(4)
Progesterone is required for the full proliferative activity of the breasts and may be directly or indirectly involved in either stimulating or inhibiting breast cancer. To determine whether the effects on breast cancer are attributable to progestero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f05b9868fdc68ef9efcfe8d45e20dcee
https://pubmed.ncbi.nlm.nih.gov/10706108
https://pubmed.ncbi.nlm.nih.gov/10706108
Autor:
J P, Wiebe
Publikováno v:
Recent progress in hormone research. 52
The release of gonadotropins is effected by GnRH and regulated by steroids. The classical mechanism of steroid hormone action, which implies the binding of hormone receptor complexes to regulatory elements of nuclear genes, is derived largely from th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2aef4c5420c920a79f482b48a752938
https://pubmed.ncbi.nlm.nih.gov/9238848
https://pubmed.ncbi.nlm.nih.gov/9238848
Publikováno v:
Journal of andrology. 15(4)
The mechanism whereby glycerol exerts its antispermatogenic action is not known. The objective of this study was to determine, with the use of [3H]inulin and [125I]albumin by in vivo and in vitro methods, whether glycerol exerts its effect by alterin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4e87075897ed92899c10c5475b93fc3
https://pubmed.ncbi.nlm.nih.gov/7982799
https://pubmed.ncbi.nlm.nih.gov/7982799
Autor:
S A, Igdoura, J P, Wiebe
Publikováno v:
Journal of andrology. 15(3)
Previous studies have shown that a single intratesticular injection with 70% glycerol results in rapid and long-term suppression of spermatogenesis. Because of the extensive testicular damage in the form of focal destruction and large numbers of acel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e3af2d5fb6fc8b483f7dfca8056f73da
https://pubmed.ncbi.nlm.nih.gov/7928665
https://pubmed.ncbi.nlm.nih.gov/7928665
Publikováno v:
Journal of Biological Chemistry. 260:10689-10697
Porcine luteal LH/hCG receptor (LH/hCG R) was solubilized with 70-80% recovery from the crude plasma membrane fraction by Triton X-100 in the presence of 25% glycerol and protease inhibitors. The solubilized receptor maintained 90% of original activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25a7b6df7d404af40e51c465935549fc
https://doi.org/10.1016/s0021-9258(19)85138-4
https://doi.org/10.1016/s0021-9258(19)85138-4
Publikováno v:
Journal of Biological Chemistry. 261:9416-9420
Purified porcine luteinizing hormone/human chorionic gonadotropin receptors were analyzed by sodium dodecyl sulfate/polyacrylamide gel electrophoresis following reduction and thermal denaturation and stained with Coomassie Brilliant Blue. A major pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::253447999f78e289ec62806c5b188064
https://doi.org/10.1016/s0021-9258(18)67671-9
https://doi.org/10.1016/s0021-9258(18)67671-9
Autor:
S M, Campbell, J P, Wiebe
Publikováno v:
Biology of reproduction. 40(4)
The effect of 3 alpha-hydroxy-4-pregnen-3-one (3HP), a Sertoli cell steroid, on spermatogenesis was examined in normal and gonadotropin-suppressed rats, through s.c. as well as direct intratesticular injections. Early experiments employing normal pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a4c0a2b2dc68f0b778f0839b475e7ca
https://pubmed.ncbi.nlm.nih.gov/2502196
https://pubmed.ncbi.nlm.nih.gov/2502196