Zobrazeno 1 - 10
of 52
pro vyhledávání: '"J P, Tarayre"'
Autor:
A, Newman-Tancredi, R, Depoortère, E, Carilla-Durand, J P, Tarayre, M, Kleven, W, Koek, L, Bardin, M A, Varney
Publikováno v:
Pharmacology, biochemistry, and behavior. 165
NLX-112 (a.k.a. F13640 or befiradol), exhibits nanomolar affinity, exceptional selectivity and high agonist efficacy at 5-hydroxytryptamine 5-HT
Publikováno v:
Pharmacology. 67(4)
Previously, we have reported that in rat models of chronic pain, in particular, the very-high-efficacy 5-HT(1A) agonist F 13640 induces unprecedented pain relief by novel neuroadaptative mechanisms that involve inverse tolerance and cooperation with
Autor:
D, Junquero, A, Pilon, E, Carilla-Durand, J F, Patoiseau, J P, Tarayre, G, Torpier, B, Staels, J C, Fruchart, F C, Colpaert, V, Clavey, A, Delhon
Publikováno v:
Biochemical pharmacology. 61(4)
Inhibition of acyl-coenzyme A: cholesterol O-acyltransferase (EC 2.3.1.26; ACAT) reduces intracellular cholesteryl esters that are substrates for steroidogenesis in adrenal cells. The adrenal side effects of ACAT inhibitors remain a key point for the
Autor:
G W, John, P J, Pauwels, M, Perez, S, Halazy, B, Le Grand, Y, Verscheure, J P, Valentin, C, Palmier, T, Wurch, P, Chopin, M, Marien, M S, Kleven, W, Koek, M B, Assie, E, Carilla-Durand, J P, Tarayre, F C, Colpaert
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 290(1)
F 11356 (4-[4-[2-(2-aminoethyl)-1H-indol-5-yloxyl]acetyl]piperazinyl-1-yl] ben zonitrile) was designed to take advantage of the superior potency and efficacy characteristics of 5-hydroxytryptamine (5-HT) compared with tryptamine at 5-HT1B/1D receptor
Publikováno v:
New Concepts in Asthma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e9fcfdd3ee5046b89c4805e02848b30
https://doi.org/10.1007/978-1-349-12673-6
https://doi.org/10.1007/978-1-349-12673-6
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 13(2)
Hyperreactivity and bronchial inflammation resulting from active anaphylactic shock induced by aerosol have been studied in guinea pigs after sensitization by intramuscular injection of large-dose ovalbumin or aerosol ovalbumin. When animals were sen
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 310
Tioxamast, an anti-allergic compound inhibiting the release and synthesis of certain mediators of allergy and having no major antagonist effect towards such mediators, was experimented on various models of anaphylactic shock, hyperreactivity and bron
Publikováno v:
Arzneimittel-Forschung. 40(10)
Various models of delayed hypersensitivity (DH) were used in mice: contact hypersensitivity reactions to picryl chloride and oxazolone and reactions to methylated bovine serum albumin (MBSA) and sheep red blood cells (SRBC). Drugs of different classe
Autor:
J P, Tarayre, M, Aliaga, M, Barbara, N, Tisseyre, V, Caillol, A, Delhon, F, Bruniquel, X, N'Guyen, L, Puech, J, Tisné-Versailles
Publikováno v:
International archives of allergy and applied immunology. 92(1)
Tioxamast (F 1865) is an antiallergic drug that, administered systemically, reduces anaphylaxis in various models in rats. This action is due mainly to the inhibition of the synthesis and release of certain mediators. Orally or intraduodenally admini
Antiallergic and anti-inflammatory action of tioxamast in rats. II. Anti-inflammatory action in vivo
Autor:
J P, Tarayre, M, Aliaga, M, Barbara, N, Tisseyre, V, Caillol, A, Delhon, F, Bruniquel, X, N'Guyen, L, Puech, J, Tisné-Versailles
Publikováno v:
International archives of allergy and applied immunology. 92(1)
Tioxamast is an antiallergic drug that inhibits anaphylaxis in various models in rats, and it inhibits the release and synthesis of certain mediators of inflammation [see Tarayre et al., this issue]. Here we report that the drug also has an anti-infl