Zobrazeno 1 - 10
of 527
pro vyhledávání: '"J P, Sauvage"'
Autor:
E., Muslimov, N., Levraud, V., Chambouleyron, I., Boudjema, A., Lau, A., Caillat, F., Pedreros, G., Otten, K., El Hadi, K., Joaquina, M., Lopez, M., El Morsy, O., Beltramo Martin, R., Fetick, Z., Ke, J-F., Sauvage, B., Neichel, T., Fusco, J., Schmitt, A., Le Van Suu, J., Charton, A., Schimpf, B., Martin, F., Dintrono, S., Esposito, E, Pina
Publikováno v:
Proc. SPIE 11876, Optical Instrument Science, Technology, and Applications II, 118760H (24 September 2021)
The Provence Adaptive optics Pyramid Run System (PAPYRUS) is a pyramid-based Adaptive Optics (AO) system that will be installed at the Coude focus of the 1.52m telescope (T152) at the Observatoire de Haute Provence (OHP). The project is being develop
Externí odkaz:
http://arxiv.org/abs/2110.10263
Autor:
Lucia Taraborrelli, Yasin Şenbabaoğlu, Lifen Wang, Junghyun Lim, Kerrigan Blake, Noelyn Kljavin, Sarah Gierke, Alexis Scherl, James Ziai, Erin McNamara, Mark Owyong, Shilpa Rao, Aslihan Karabacak Calviello, Daniel Oreper, Suchit Jhunjhunwala, Guillem Argiles, Johanna Bendell, Tae Won Kim, Fortunato Ciardiello, Matthew J. Wongchenko, Frederic J. de Sauvage, Felipe de Sousa e Melo, Yibing Yan, Nathaniel R. West, Aditya Murthy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Microsatellite-stable colorectal cancer (MSS-CRC) is highly refractory to immunotherapy. Understanding tumor-intrinsic determinants of immunotherapy resistance is critical to improve MSS-CRC patient outcomes. Here, we demonstrate that high t
Externí odkaz:
https://doaj.org/article/60a294e8ef9e4b37a641c0c3e8919afe
Autor:
Keren Bahar Halpern, Hassan Massalha, Rachel K. Zwick, Andreas E. Moor, David Castillo-Azofeifa, Milena Rozenberg, Lydia Farack, Adi Egozi, Dan R. Miller, Inna Averbukh, Yotam Harnik, Noa Weinberg-Corem, Frederic J. de Sauvage, Ido Amit, Ophir D. Klein, Michal Shoshkes-Carmel, Shalev Itzkovitz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Epithelial gene expression has been shown to be zonated along the crypt-villus axis, but mechanisms shaping this spatial variability were unknown. Here, Bahar Halpern et al. uncover zonation of mesenchymal cells, including Lgr5+ telocytes, which regu
Externí odkaz:
https://doaj.org/article/06a4059134d14359ba2c09cd1b2ad006
Autor:
Ganapati V Hegde, Cecile de la Cruz, Jennifer M Giltnane, Lisa Crocker, Avinashnarayan Venkatanarayan, Gabriele Schaefer, Debra Dunlap, Joerg D Hoeck, Robert Piskol, Florian Gnad, Zora Modrusan, Frederic J de Sauvage, Christian W Siebel, Erica L Jackson
Publikováno v:
eLife, Vol 8 (2019)
Squamous cell carcinomas (SCCs) account for the majority of cancer mortalities. Although TP63 is an established lineage-survival oncogene in SCCs, therapeutic strategies have not been developed to target TP63 or it’s downstream effectors. In this s
Externí odkaz:
https://doaj.org/article/6f4e75535ef4450d90e11913cada4356
Autor:
Stephanie Grabow, Andrew J. Kueh, Francine Ke, Hannah K. Vanyai, Bilal N. Sheikh, Michael A. Dengler, William Chiang, Samantha Eccles, Ian M. Smyth, Lynelle K. Jones, Frederic J. de Sauvage, Mark Scott, Lachlan Whitehead, Anne K. Voss, Andreas Strasser
Publikováno v:
Cell Reports, Vol 24, Iss 12, Pp 3285-3295.e4 (2018)
Summary: Apoptotic cell death removes unwanted cells and is regulated by interactions between pro-survival and pro-apoptotic members of the BCL-2 protein family. The regulation of apoptosis is thought to be crucial for normal embryonic development. A
Externí odkaz:
https://doaj.org/article/b958c8def9dc4e4eb7387f18421e59a4
Autor:
Hua Tian, Brian Biehs, Cecilia Chiu, Christian W. Siebel, Yan Wu, Mike Costa, Frederic J. de Sauvage, Ophir D. Klein
Publikováno v:
Cell Reports, Vol 11, Iss 1, Pp 33-42 (2015)
Proper organ homeostasis requires tight control of adult stem cells and differentiation through the integration of multiple inputs. In the mouse small intestine, Notch and Wnt signaling are required both for stem cell maintenance and for a proper bal
Externí odkaz:
https://doaj.org/article/ae315e37a59046079e29477b41c2bcdc
Autor:
J.-P. Sauvage
Publikováno v:
Laboratory and production. 8:10-17
Autor:
Kui Lin, James R Taylor, Thomas D Wu, Johnny Gutierrez, J Michael Elliott, Jean-Michel Vernes, Hartmut Koeppen, Heidi S Phillips, Frederic J de Sauvage, Y Gloria Meng
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18608 (2011)
BACKGROUND: TMEFF2 is a protein containing a single EGF-like domain and two follistatin-like modules. The biological function of TMEFF2 remains unclear with conflicting reports suggesting both a positive and a negative association between TMEFF2 expr
Externí odkaz:
https://doaj.org/article/9a9b90e946d248ae8924316815b18427
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Publikováno v:
Journal Français d'Ophtalmologie. 29:961-964
Granulocytic sarcoma in a 90-year-old patient Granulocytic sarcoma rarely involves the orbit. It is the local proliferation of immature myeloid cells and occurs most often in patients suffering from myelodysplastic syndromes. We report a case of gran