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Autor:
Marc Dorais, Patrice Paiement, Johanne Martel-Pelletier, François Abram, J.-P. Pelletier, J.-P. Raynauld
Publikováno v:
Annals of the Rheumatic Diseases. 79:188.1-188
Background:Intra-articular corticosteroid injections (IACI) are commonly used for the treatment of symptomatic knee osteoarthritis (OA) and therapeutic guidelines have recommended their use. However, their safety regarding the evolution of structural
Publikováno v:
Annals of the Rheumatic Diseases. 79:1744.1-1744
Background:The DISSCO trial (6-month international, multicentre, double-blind, randomised study on the effect of diacerein vs celecoxib in symptomatic knee osteoarthritis [OA] patients) showed that diacerein had comparable efficacy to celecoxib at re
Autor:
J.-P. Pelletier, Louis Bessette, D. Sauvageau, L. Coupal, Edith Villeneuve, Isabelle Ferdinand, J.-P. Raynauld, Boulos Haraoui, Denis Choquette, Frédéric Massicotte, M.-A. Rémillard, L. Choquette Sauvageau
Publikováno v:
Annals of the Rheumatic Diseases. 79:1467.1-1467
Background:Since the introduction of biologic agents around the turn of the century, the scientific evidence shows that the majority of agents, independent of the therapeutic target, have a better outcome when used in combination with methotrexate (M
Autor:
Johanne Martel-Pelletier, J.-P. Pelletier, Marc Dorais, J. Rousseau Trépanier, J.-P. Raynauld, François Abram, Ginette Tardif
Publikováno v:
Osteoarthritis and cartilage. 27(8)
Summary Objective There is a need to identify reliable biomarkers that can predict knee osteoarthritis (OA) progression. We investigated a panel of adipokines and some related inflammatory factors alone and their ratios for their associative value at
Autor:
Thomas M. Link, Felix Eckstein, J.-P. Pelletier, Johanne Martel-Pelletier, Frank W. Roemer, Colin G. Miller, G.E. Gold, S. Totterman, Richard Kijowski, R.E. Ochoa-Albíztegui, J.-P. Raynauld, Jeff Duryea, Roy D. Altman, Michel D. Crema, C. Peterfy, Timothy J. Mosher, David J. Hunter, Flavia M. Cicuttini, Ali Guermazi
Publikováno v:
Osteoarthritis and Cartilage. 23(5):698-715
SummarySignificant advances have occurred in our understanding of the pathogenesis of knee osteoarthritis (OA) and some recent trials have demonstrated the potential for modification of the disease course. The purpose of this expert opinion, consensu
Autor:
J.-P. Raynauld, Roelien Postema, D. Sauvageau, M Mtibaa, Frédéric Massicotte, J.-P. Pelletier, M-A Rémillard, E Muratti, Evo Alemao, Boulos Haraoui, Louis Bessette, L. Coupal, Έ. Villeneuve, A Turcotte, Denis Choquette
Publikováno v:
Abstracts Accepted for Publication.
Background In the absence of biomarkers predicting response to a specific therapy, the choice of second biologic is based mostly on habit and availability of an alternative agent. Traditionally, a second anti-TNF was the preferred option, but recent
Autor:
M Mtibaa, E Muratti, J.-P. Pelletier, Frédéric Massicotte, J.-P. Raynauld, Roelien Postema, Boulos Haraoui, M-A Rémillard, Evo Alemao, L. Coupal, Louis Bessette, Έ. Villeneuve, D. Sauvageau, A Turcotte, Denis Choquette
Publikováno v:
Poster Presentations.
Background Sustainability of treatment is important to consider when selecting a therapy for chronic conditions such as RA. Sustainability is a useful clinical marker for both long-term efficacy and safety. A recently published randomized controlled
Autor:
D Choquette, L Bessette, B Haraoui, F Massicotte, J-P Pelletier, J-P Raynauld, M-A Rémillard, D Sauvageau, A Turcotte, Έ Villeneuve, L Coupal
Publikováno v:
Poster Presentations.
Autor:
J. Caron, Boulos Haraoui, J.-P. Raynauld, Denis Choquette, François Abram, J.-P. Pelletier, François Mineau, Johanne Martel-Pelletier, Marc Dorais
Publikováno v:
Annals of the Rheumatic Diseases. 69:2095-2101
ObjectivesTo explore the impact of disease-modifying osteoarthritis drug (DMOAD) treatment on biomarker levels and their correlation with cartilage volume loss and disease symptoms in a 2-year phase III clinical trial in patients with knee OA.Methods