Výsledky vyhledávání - "J P, Quigley"

Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP). The role of the cytoplasmic tail Cys(574), the active site Glu(240), and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in breast carcinoma cells

Autor: D V, Rozanov, E I, Deryugina, B I, Ratnikov, E Z, Monosov, G N, Marchenko, J P, Quigley, A Y, Strongin

Publikováno v: The Journal of biological chemistry. 276(28)

Membrane type-1 matrix metalloproteinase (MT1-MMP) is a key enzyme in the activation pathway of matrix prometalloproteinase-2 (pro-MMP-2). Both activation and autocatalytic maturation of pro-MMP-2 in trans suggest that MT1-MMP should exist as oligome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::789b3725a8b0a44a801018d72654dc07
https://pubmed.ncbi.nlm.nih.gov/11335709

Zobrazit plný text záznamu

The isolation, characterization, and molecular cloning of a 75-kDa gelatinase B-like enzyme, a member of the matrix metalloproteinase (MMP) family. An avian enzyme that is MMP-9-like in its cell expression pattern but diverges from mammalian gelatinase B in sequence and biochemical properties

Autor: E A, Hahn-Dantona, R T, Aimes, J P, Quigley

Publikováno v: The Journal of biological chemistry. 275(52)

We have isolated a novel 75-kDa gelatinase from a chicken macrophage cell line, HD11. Biochemical and immunological characterization of the purified enzyme demonstrated that it is distinct from the chicken 72-kDa gelatinase A (MMP-2). The enzyme is c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::05981084f20d49a4039ca97d5c71bea7
https://pubmed.ncbi.nlm.nih.gov/11010969

Zobrazit plný text záznamu

MMP-2 expression during early avian cardiac and neural crest morphogenesis

Autor: D H, Cai, T M, Vollberg, E, Hahn-Dantona, J P, Quigley, P R, Brauer

Publikováno v: The Anatomical record. 259(2)

Matrix metalloproteinase-type 2 (MMP-2) degrades extracellular matrix, mediates cell migration and tissue remodeling, and is implicated in mediating neural crest (NC) and cardiac development. However, there is little information regarding the express

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8c4ffec07be3aecd604437d2254e320e
https://pubmed.ncbi.nlm.nih.gov/10820319

Zobrazit plný text záznamu

Binding of alpha2-macroglobulin and limulin: regulation of the plasma haemolytic system of the American horseshoe crab, Limulus

Autor: S, Swarnakar, R, Asokan, J P, Quigley, P B, Armstrong

Publikováno v: The Biochemical journal.

The mediator of haemolysis in the plasma of the horseshoe crab, Limulus polyphemus, is limulin, a sialic acid-binding lectin. The haemolytic activity of limulin is inhibited by thiol ester-reacted forms of Limulus alpha(2)-macroglobulin, the third-mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::07f8b8ef01e5304e3379832ecc0f2953
https://pubmed.ncbi.nlm.nih.gov/10769170

Zobrazit plný text záznamu

Alpha2-macroglobulin does not function as a C3 homologue in the plasma hemolytic system of the American horseshoe crab, Limulus

Autor: P B, Armstrong, R, Melchior, S, Swarnakar, J P, Quigley

Publikováno v: Molecular immunology. 35(1)

A major problem of comparative immunology is the characterization of the internal defense systems that lyse foreign cells, such as bacteria and other microbial pathogens that have gained entry into the body. The plasma cytolytic system of the America

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a4c6259e47e12cd581974208f85808b
https://pubmed.ncbi.nlm.nih.gov/9683263

Zobrazit plný text záznamu

Autoactivation of avian urokinase-type plasminogen activator (uPA). A novel mode of initiation of the uPA/plasmin cascade

Autor: D S, Alexander, J D, Sipley, J P, Quigley

Publikováno v: The Journal of biological chemistry. 273(13)

In contrast to mammalian urokinase-type plasminogen activator (uPA), which is produced and maintained in zymogen form, avian uPA is found in the active two-chain form in cultures of normal and transformed chicken cells in the absence of plasmin, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::50b2e534f102854a3161a193c1a0becf
https://pubmed.ncbi.nlm.nih.gov/9516444

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání