Zobrazeno 1 - 5
of 5
pro vyhledávání: '"J P, Priestle"'
Publikováno v:
Journal of computer-aided molecular design. 13(6)
This paper describes the construction, validation and application of an active site model of the serine protease thrombin. Initial use was made of medium resolution X-ray crystallographic structures of thrombin complexed with low molecular weight, no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7998fda4add2231597470c1aca2575b9
https://pubmed.ncbi.nlm.nih.gov/10584216
https://pubmed.ncbi.nlm.nih.gov/10584216
Publikováno v:
Advances in experimental medicine and biology. 379
As known from the x-ray crystal structure in complex with a proteinase and from NMR studies, the serine proteinase inhibitor eglin c has a wedge-like shape with a hydrophobic core and a solvent exposed active site binding loop which is stabilized by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::606efbfe368377196eed1d31f83eaeb5
https://pubmed.ncbi.nlm.nih.gov/8796309
https://pubmed.ncbi.nlm.nih.gov/8796309
Autor:
J P, Priestle
Publikováno v:
Structure (London, England : 1993). 2(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c639149cef85872bbad2f1d08f24c07
https://pubmed.ncbi.nlm.nih.gov/7866742
https://pubmed.ncbi.nlm.nih.gov/7866742
Publikováno v:
Journal of molecular biology. 217(2)
The crystal structures of the complexes formed between subtilisin Novo and three inhibitors, eglin c, Arg45-eglin c and Lys53-eglin c have been determined using molecular replacement and difference Fourier techniques and refined at 2.4 A, 2.1 A, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0c8ea8b1ca94818c81d6ace83ef6e9d
https://pubmed.ncbi.nlm.nih.gov/1992167
https://pubmed.ncbi.nlm.nih.gov/1992167
Autor:
J. P. Priestle
Publikováno v:
Journal of Applied Crystallography. 21:572-576
A suite of Fortran computer programs is described which generates simplified stereo schematic drawings (cartoons) of protein structures similar to the hand-drawn figures of Richardson [Methods Enzymol. (1985), 115, 359–380]. α-helices are represen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f053ec38618a61f55ada2c6ccf7692d6
https://doi.org/10.1107/s0021889888005746
https://doi.org/10.1107/s0021889888005746