Zobrazeno 1 - 10
of 127
pro vyhledávání: '"J P, Lynch"'
Autor:
R. P. Cornish, M. C. Magnus, S. K. Urhoj, G. Santorelli, L. G. Smithers, D. Odd, A. Fraser, S. E. Håberg, A. M. Nybo Andersen, K. Birnie, J. W. Lynch, K. Tilling, D. A. Lawlor
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Preterm birth (PTB) is a leading cause of child morbidity and mortality. Evidence suggests an increased risk with both maternal underweight and obesity, with some studies suggesting underweight might be a greater factor in spontan
Externí odkaz:
https://doaj.org/article/3577063e8394446695dc19e281c095e5
Autor:
Bajram Ferizoli, Alexander J. Cresswell-Boyes, Paul Anderson, Richard J. M. Lynch, Robert G. Hill
Publikováno v:
Frontiers in Dental Medicine, Vol 4 (2023)
IntroductionFluoride plays a major role in inhibiting enamel dissolution and promoting fluorapatite formation. Porous hydroxyapatite (HAP) discs can be used as an enamel analogue in artificial demineralisation/remineralisation studies.MethodThe aim o
Externí odkaz:
https://doaj.org/article/b244d91198034431a4159d07ac23e146
Autor:
Jonathan M. Roberts, David J. Bradshaw, Richard J. M. Lynch, Susan M. Higham, Sabeel P. Valappil
Publikováno v:
PLoS ONE, Vol 16, Iss 10 (2021)
Evidence on the link between starch intake and caries incidence is conflicting, therefore the cariogenicity of starch compared with sucrose was explored using a dual Constant Depth Film Fermenter (dCDFF) biotic model system. Bovine enamel discs were
Externí odkaz:
https://doaj.org/article/48c1952914834b04b93781dc0e48e6ca
Autor:
Sofia Noli Truant, Mauricio C. De Marzi, María B. Sarratea, María B. Antonoglou, Ana P. Meo, Laura V. Iannantuono López, María J. Fernández Lynch, Marcos Todone, Emilio L. Malchiodi, Marisa M. Fernández
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Bacterial superantigens (SAgs) are enterotoxins that bind to MHC-II and TCR molecules, activating as much as 20% of the T cell population and promoting a cytokine storm which enhances susceptibility to endotoxic shock, causing immunosuppression, and
Externí odkaz:
https://doaj.org/article/6ca271635383458bba0c0f37df1bb984
Autor:
Roger D. Klein, Qin Shu, Zachary T. Cusumano, Kanna Nagamatsu, Nathaniel C. Gualberto, Aaron J. L. Lynch, Chao Wu, Wenjie Wang, Neha Jain, Jerome S. Pinkner, Gaya K. Amarasinghe, Scott J. Hultgren, Carl Frieden, Matthew R. Chapman
Publikováno v:
mBio, Vol 9, Iss 4 (2018)
ABSTRACT Curli amyloid fibers are produced as part of the extracellular biofilm matrix and are composed primarily of the major structural subunit CsgA. The CsgE chaperone facilitates the secretion of CsgA through CsgG by forming a cap at the base of
Externí odkaz:
https://doaj.org/article/ff37b00ca12f43a9a3727996214c28c6
Autor:
Cristina Colomer-Winter, Ana L Flores-Mireles, Shannon P Baker, Kristi L Frank, Aaron J L Lynch, Scott J Hultgren, Todd Kitten, José A Lemos
Publikováno v:
PLoS Pathogens, Vol 14, Iss 9, p e1007102 (2018)
Manganese (Mn) is an essential micronutrient that is not readily available to pathogens during infection due to an active host defense mechanism known as nutritional immunity. To overcome this nutrient restriction, bacteria utilize high-affinity tran
Externí odkaz:
https://doaj.org/article/cdb0bc08bac14863a8553f0dcc1b51a2
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Introduction: Tooth enamel mineral loss is influenced by its solubility product value, which is fundamental to the understanding of de- and remineralization resulting from a carious or erosive challenge. Published pKsp values for human enamel and hyd
Externí odkaz:
https://doaj.org/article/6d79dbb9297c42b792d320cc51fa25d1
Autor:
R. A. Ellis, D. J. Jacob, M. P. Sulprizio, L. Zhang, C. D. Holmes, B. A. Schichtel, T. Blett, E. Porter, L. H. Pardo, J. A. Lynch
Publikováno v:
Atmospheric Chemistry and Physics, Vol 13, Iss 17, Pp 9083-9095 (2013)
National parks in the United States are protected areas wherein the natural habitat is to be conserved for future generations. Deposition of anthropogenic nitrogen (N) transported from areas of human activity (fuel combustion, agriculture) may affect
Externí odkaz:
https://doaj.org/article/54bb58f94b064ba28e0c8a3a9d167eae
Autor:
María B Ganem, Mauricio C De Marzi, María J Fernández-Lynch, Carolina Jancic, Mónica Vermeulen, Jorge Geffner, Roy A Mariuzza, Marisa M Fernández, Emilio L Malchiodi
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66244 (2013)
Bacterial superantigens (SAgs) are exotoxins produced mainly by Staphylococcus aureus and Streptococcus pyogenes that can cause toxic shock syndrome (TSS). According to current paradigm, SAgs interact directly and simultaneously with T cell receptor
Externí odkaz:
https://doaj.org/article/78c3822b17e245c0b83ddbeb11ce18d7
Autor:
S. Sam Weigt, J P Lynch rd, Aric L. Gregson, Michael Y. Shino, David J. Ross, John A. Belperio, Robert Elashoff, Ning Li, Rajan Saggar, Ariss Derhovanessian, Richard H. Huynh, Abbas Ardehali, David M. Sayah
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, vol 18, iss 1
The clinical significance and treatment strategies for minimal acute rejection (grade A1), the most common form of acute rejection (AR), remain controversial. In this retrospective single-center cohort study of 441 lung transplant recipients, we form