Zobrazeno 1 - 10
of 16
pro vyhledávání: '"J P, Leek"'
Autor:
J. P. Leek, T. P. Moynihan, Alex F. Markham, Philip A. Robinson, H. C. Ardley, J. Thompson, N. S. Brindle
Publikováno v:
Mammalian Genome. 7:520-525
Ubiquitin-conjugating enzymes (E2s) are essential components of the post-translational protein ubiquitination pathway, mediating the transfer of activated ubiquitin to substrate proteins. We have identified a human gene, UBE2L3, localized on Chromoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5532bea21ca9d0d69511e3acf18d9f2d
https://doi.org/10.1007/s003359900155
https://doi.org/10.1007/s003359900155
Autor:
Daniel J. Pearce, J P Leek, M P Blundell, S J Howe, Dominique Bonnet, Alex F. Markham, Yasser M. El-Sherbiny, E A de Wynter, Graham P. Cook, Sally A Boxall
Publikováno v:
Bone marrow transplantation. 43(8)
We have demonstrated previously that cord blood CD133(+) cells isolated in the G(0) phase of the cell cycle are highly enriched for haematopoietic stem cell (HSC) activity, in contrast to CD133(+)G(1) cells. Here, we have analysed the phenotype and f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c587b4918c3be6eee9bbea879abe71
https://pubmed.ncbi.nlm.nih.gov/18997827
https://pubmed.ncbi.nlm.nih.gov/18997827
Publikováno v:
Gene therapy. 12(4)
Herpesvirus-based gene therapy vectors offer an attractive alternative to retroviral vectors because of their episomal nature and ability to accommodate large transgenes. Saimiriine herpesvirus 2 (HVS) is a prototypical gamma-2 herpesvirus that can l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b2513e75e508890fa4a6f462292df1
https://pubmed.ncbi.nlm.nih.gov/15616605
https://pubmed.ncbi.nlm.nih.gov/15616605
Publikováno v:
Cytogenetics and cell genetics. 90(3-4)
The specificity of the ubiquitin degradation system is regulated through interaction between individual ubiquitin-conjugating enzymes (E2s) and multiple ubiquitin-protein ligases (E3s). Here we describe the characterisation of a novel gene (ARIH1) th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4bafdcbd8bb2ed89c3bfbab693549f3
https://pubmed.ncbi.nlm.nih.gov/11124525
https://pubmed.ncbi.nlm.nih.gov/11124525
Autor:
R, Achuthan, S M, Bell, J P, Leek, P, Roberts, K, Horgan, A F, Markham, P J, Selby, K A, MacLennan
Publikováno v:
Genes, chromosomescancer. 29(4)
Interest has focused on a recently identified gene, BCL10, thought to play an important role in the genesis of extranodal, marginal zone (MALT) lymphomas. This gene belongs to a family containing caspase recruitment domains (CARD), that are involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef306641340e6d9036db38b482ea70b7
https://pubmed.ncbi.nlm.nih.gov/11066079
https://pubmed.ncbi.nlm.nih.gov/11066079
Publikováno v:
Cytogenetics and cell genetics. 84(1-2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09bd1d757830aa397bdebc180189b7f5
https://pubmed.ncbi.nlm.nih.gov/10343124
https://pubmed.ncbi.nlm.nih.gov/10343124
Publikováno v:
Cytogenetics and cell genetics. 83(1-2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b09be265b3aa152233fca20cf499ced
https://pubmed.ncbi.nlm.nih.gov/9925943
https://pubmed.ncbi.nlm.nih.gov/9925943
Autor:
P J, Hamlin, P F, Jones, J P, Leek, K, Bransfield, N J, Lench, M A, Aldersley, P D, Howdle, A F, Markham, P A, Robinson
Publikováno v:
Cytogenetics and cell genetics. 82(3-4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1fe30d6b656b097b65ac9dc8617c5b77
https://pubmed.ncbi.nlm.nih.gov/9858832
https://pubmed.ncbi.nlm.nih.gov/9858832
Publikováno v:
Cytogenetics and cell genetics. 82(1-2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::877add1f2aa9b02fa371dd548c95217a
https://pubmed.ncbi.nlm.nih.gov/9763669
https://pubmed.ncbi.nlm.nih.gov/9763669
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 6(8)
Null mutations in the glucokinase (GCK) gene can cause autosomal dominant type 2 diabetes (maturity onset diabetes of the young, MODY); however, MODY is genetically heterogeneous. In both liver and pancreatic islet, glucokinase is subject to inhibiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56776a0d262dadc299a26f3d3cf9c10
https://pubmed.ncbi.nlm.nih.gov/8589523
https://pubmed.ncbi.nlm.nih.gov/8589523