Zobrazeno 1 - 10
of 114
pro vyhledávání: '"J P, Lecocq"'
Autor:
R, Andrianne, C, Bellekens, B, Sanou, P, Honoré, C, Desaive, M, Doupagne, F, Burkhard, X, Capelle, A, Kaba, J P, Lecocq, J, Gilles, G, Kaboré, D, Ouaedraogo
Publikováno v:
Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie. 32(7)
Autor:
R. J. Pierce, J. M. Balloul, J. M. Grzych, C. Dissous, C. Auriault, D. Boulanger, M. Capron, P. Sondermeyer, J. P. Lecocq, A. Capron
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 82, Pp 111-114 (1987)
Three antigens protective against Schistosoma mansoni have been extensively characterized. The schistosomulum surface antigen GP38 possesses an immunodominant carbohydrate epitope of which the structure has been defined. Protection can be achieved vi
Externí odkaz:
https://doaj.org/article/4b1969f7d1884f929a7005ae81764e94
Autor:
J. Bijman, W. Dalemans, M. Kansen, J. Keulemans, E. Verbeek, A. Hoogeveen, H. De Jonge, M. Wilke, D. Dreyer, J. P. Lecocq, al. et
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 264:L229-L235
The properties of the cystic fibrosis gene product (CFTR) were studied by expression of cloned cDNA in different cell systems. Infection of both simian fibroblast (Vero) cells and immortalized CF nasal polyp cells (NCF3A) with a vaccinia virus encodi
Autor:
Michel Perricaudet, Ronald G. Crystal, J P Lecocq, Melissa A. Rosenfeld, Andrea Pavirani, Andrea Mastrangeli, Claire Danel, L D Stratford-Perricaudet
Publikováno v:
Journal of Clinical Investigation. 91:225-234
A variety of pulmonary disorders, including cystic fibrosis, are potentially amenable to treatment in which a therapeutic gene is directly transferred to the bronchial epithelium. This is difficult to accomplish because the majority of airway epithel
Autor:
A Pavirani, Ronald G. Crystal, W Dalemans, Joachim Bargon, Bruce C. Trapnell, Kazuhisa Yoshimura, J P Lecocq
Publikováno v:
Journal of Biological Chemistry. 267:16056-16060
Epithelial cells utilize at least two types of apical Cl- channels, the cAMP-activated cystic fibrosis transmembrane conductance regulator (CFTR) and the Ca2+/calmodulin-dependent Cl- channel. While phorbal ester (PMA) activates only CFTR-dependent C
Autor:
Ronald G. Crystal, Kazuhisa Yoshimura, Hidenori Nakamura, W Dalemans, J P Lecocq, Bruce C. Trapnell, A Pavirani
Publikováno v:
Journal of Biological Chemistry. 266:9140-9144
Evaluation of the expression of the cystic fibrosis (CF) gene in human epithelial cell lines demonstrated active, but low level, transcription of the gene. Analysis of 3.8 kilobases of genomic sequences 5' to exon 1 of the CF gene demonstrated no TAT
Publikováno v:
Journal of Virology. 65:1325-1331
The Vif protein of human immunodeficiency virus type 1 (HIV-1) regulates viral infectivity. Virions produced in cell culture after transfection by a Vif-negative molecular clone show a dramatic decrease in infectivity for susceptible CD4+ cell lines,
Autor:
J P Lecocq, Wilfried Dalemans, Kazuhisa Yoshimura, Chin-Shyan Chu, Bruce C. Trapnell, Hidenori Nakamura, Ronald G. Crystal, Andrea Pavirani
Publikováno v:
Nucleic Acids Research. 19:5417-5423
Consistent with the fact that the clinical disorder cystic fibrosis (CF) is manifested on epithelial surfaces, active transcription of the CF transmembrane conductance regulator (CFTR) gene and CFTR mRNA transcripts are detectable in a variety of epi
Autor:
Helene Gras-Masse, Anne-Marie Schacht, André Capron, A Tartar, Jean-Marie Grzych, J P Lecocq, Raymond J. Pierce, Jamal Khalife, Jean-Claude Ameisen
Publikováno v:
The Journal of Experimental Medicine
A monoclonal antibody (mAb) directed against a synthetic peptide derived from the sequence of the human immunodeficiency virus type 1 (HIV-1) regulatory protein virion infectivity factor (vif) labeled the surface of Schistosoma mansoni schistosomula
Autor:
W Siegfried, Michel Perricaudet, Melissa A. Rosenfeld, L D Stratford-Perricaudet, L Stier, Andrea Pavirani, J P Lecocq, Ronald G. Crystal
Publikováno v:
American journal of respiratory cell and molecular biology. 12(4)
alpha 1-Antitrypsin (alpha AT) deficiency, a hereditary cause of progressive emphysema, can potentially be treated by transfer of a functional human alpha 1AT gene to the respiratory epithelium. For such an approach to be successful, alpha 1AT must b