Výsledky vyhledávání - "J P, Heggers"

Is the Limulus Amebocyte Lysate the Sole Predictor of Septic Episodes in Major Thermal Injuries?

Autor: C Maness, J. P. Heggers, R J Ramirez, L McCoy, E. Carino, R. Goodheart

Publikováno v: Journal of Burn Care & Rehabilitation. 19:512-515

Septic episodes in thermal injuries are usually hallmarked by a series of physiologic parameters that include tachypnea, prolonged paralytic ileus, hyperthermia or hypothermia, altered mental status, thrombocytopenia, leukocytosis or unexplained leuk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::592395265adfa463f87f2aeaac46f1bb
https://doi.org/10.1097/00004630-199811000-00009

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Much ado about nothing: methicillin-resistant Staphylococcus aureus

Autor: T, Shannon, P, Edgar, C, Villarreal, D N, Herndon, L G, Phillips, J P, Heggers

Publikováno v: The Journal of burn carerehabilitation. 18(4)

The pathogenic methicillin-resistant Staphylococcus aureus (MRSA) has received a voluminous amount of notoriety. The four major reasons are its morbidity, mortality rate, cost of treatment, and constant appearance in intensive care units. Both Staphy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c1972a7a7853732dd6f29b9158efd025
https://pubmed.ncbi.nlm.nih.gov/9261699

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Pseudomonas aeruginosa exotoxin A: its role in retardation of wound healing: the 1992 Lindberg Award

Autor: J P, Heggers, S, Haydon, F, Ko, P G, Hayward, S, Carp, M C, Robson

Publikováno v: The Journal of burn carerehabilitation. 13(5)

Bacterial concentrations greater than 10(5) colony-forming units/gm of tissue prevent wound healing. However, it has not been determined whether it is the number of bacteria or a toxin produced by these organisms that impedes the wound healing proces

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b072ae075457b89e8b1b41dcf8d56b81
https://pubmed.ncbi.nlm.nih.gov/1452584

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Enhancement of incisional wound healing and neovascularization in normal rats by thrombin and synthetic thrombin receptor-activating peptides

Autor: R Mann, C Annable, J Christie, W R Redin, S D Pernia, Berry Dl, P G Hayward, M C Robson, D H Carney, J P Heggers

To better define thrombin-receptor interactions, we synthesized human thrombin peptides and identified binding-domain peptides that bind thrombin receptors and activate mitogenic signals (Glenn, K.C., G.H. Frost, J.S. Bergmann, and D.H. Carney. 1988.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384adec23171e9406a06878fa7b3b8fd
https://europepmc.org/articles/PMC443017/

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Effects of thromboxane synthetase inhibition on postburn mesenteric vascular resistance and the rate of bacterial translocation in a chronic porcine model

Autor: R, Tokyay, H M, Loick, D L, Traber, J P, Heggers, D N, Herndon

Publikováno v: Surgery, gynecologyobstetrics. 174(2)

It is known that thromboxane (TX)B2, the metabolite of the potent vasoconstrictor TXA2, is elevated markedly in the serum of the patients immediately postburn. We had shown that extensive thermal injury causes a reduction in mesenteric blood flow tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cd0ff5e86bf27d554ecf2253fcc8e55c
https://pubmed.ncbi.nlm.nih.gov/1734570

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Clinical studies on growth factors in pressure sores: preliminary report

Autor: M C, Robson, L G, Phillips, J P, Heggers, M A, McPherson, L S, Heiner

Publikováno v: Progress in clinical and biological research. 365

Agents touted to benefit chronic non-healing wounds will become evermore prevalent. Examples, in addition to those cited, might include epictor (EGF) or platelet derived growth factor (PDGF). Although they may look promising in in vitro and experimen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::311452442f17d8e2e51433735000404a
https://pubmed.ncbi.nlm.nih.gov/1862156

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Topical Bactroban (mupirocin): efficacy in treating burn wounds infected with methicillin-resistant staphylococci

Autor: L L, Strock, M M, Lee, R L, Rutan, M H, Desai, M C, Robson, D N, Herndon, J P, Heggers

Publikováno v: The Journal of burn carerehabilitation. 11(5)

Bacterial antimicrobial susceptibility predictors such as the minimal inhibitory concentration (MIC) assay and Nathans Agar Well Diffusion (NAWD) assay provide essential information relevant to the therapeutic approach in burn-wound sepsis. The susce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dfe00cd4d3c701fc5fac12c38a74df48
https://pubmed.ncbi.nlm.nih.gov/2123203

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Wound healing alterations caused by infection

Autor: M C, Robson, B D, Stenberg, J P, Heggers

Publikováno v: Clinics in plastic surgery. 17(3)

The theoretical alterations of wound healing caused by infection apply to the clinical situation. The level of bacteria is clinically important as are the specific qualities of a given species. This latter consideration has not been as completely stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d1a1b69860fa30ccc286728bc9e3db7e
https://pubmed.ncbi.nlm.nih.gov/2199139

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Klebsiella: Harmless to Problematic

Autor: E. Carino, J. W. Washington, A. Sanford, L McCoy, P. Edgar, J. P. Heggers

Publikováno v: American Journal of Infection Control. 32:E17

BACKGROUND: Klebsiella pneumoniae (KPNE), previously an innocuous bug in our pediatric burn unit, changed its characteristics recently. A 13-year-old male was admitted from Mexico with a third-degree 60% TBSA flame burn. We isolated from his burn wou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4df678b3fc95ab975058ce85afd6524b
https://doi.org/10.1016/j.ajic.2004.04.024

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