Zobrazeno 1 - 10
of 69
pro vyhledávání: '"J P, Hérault"'
Autor:
P. Schaeffer, P Savi, F. Bono, Jean-Marc Herbert, M. Petitou, P. Duchaussoy, J P Hérault, L. Millet
Publikováno v:
Journal of Thrombosis and Haemostasis. 6:1697-1706
Summary. Objective: In order to obtain a neutralizable antithrombotic, a chimeric molecule (SSR126517E) containing the sequence of a long-lasting antithrombin (AT)-dependent anti-factor Xa pentasaccharide, idraparinux, linked to a biotin molecule was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965cc9ebb0253d70fbb026808160d0db
https://doi.org/10.1111/j.1538-7836.2008.03089.x
https://doi.org/10.1111/j.1538-7836.2008.03089.x
Autor:
Pierre Fons, Jacques Bonnin, Antoine Alam, Marie Mandron, J. P. Hérault, Pauline Barron, Gera Neufeld, Francoise Bono, Benoit Favier, Pierre Savi, Jean-Marc Herbert, Patricia Laboudie
Publikováno v:
Blood. 108:1243-1250
Neuropilin 2 (NRP2) is a receptor for the vascular endothelial growth factor (VEGF) and the semaphorin (SEMA) families, 2 unrelated ligand families involved in angiogenesis and neuronal guidance. NRP2 specifically binds VEGF-A and VEGF-C, although th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa32f9ec73ef9aa2ee553fda2901309
https://doi.org/10.1182/blood-2005-11-4447
https://doi.org/10.1182/blood-2005-11-4447
Autor:
C. Gaich, Françoise Bono, J. M. Herbert, Petitou Maurice, Pierre-Alexandre Driguez, J. P. Hérault, P. Duchaussoy
Publikováno v:
Thrombosis and Haemostasis. 88:432-435
SummaryWe investigated the effect of various oligosaccharides (OS) on the inhibition of factor IXa by antithrombin (AT) in a purified system. The OS comprised the AT-binding pentasaccharide sequence prolonged by saccharide chains with various lengths
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9d81d8b66b29f57646d64039e724bf4
https://doi.org/10.1055/s-0037-1613234
https://doi.org/10.1055/s-0037-1613234
Publikováno v:
Thrombosis and Haemostasis. 87:238-244
SummaryThe effect of new heparin mimetics (synthetic oligosaccharides) was studied in vitro with regard to thrombin generation (TG) in rat platelet rich plasma (PRP) and whole blood (WB) and in vivo on stasis-induced venous thrombosis in the rat.TG i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c78dcf7af191ee76170cf9f16cc22731
https://doi.org/10.1055/s-0037-1612979
https://doi.org/10.1055/s-0037-1612979
Autor:
Françoise Bono, Petitou Maurice, F. Roye, Andre Bernat, J. P. Hérault, J. M. Herbert, C. Michaux, Paul J. Schaeffer
Publikováno v:
Thrombosis and Haemostasis. 87:985-989
SummaryPharmacokinetics of oligosaccharides displaying various affinities for antithrombin (AT) allowed us to show that there was a close relationship between the plasma half-life of these antithrombotic oligosaccharides and their affinity for AT. Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b34ddbe29b4a6d70a955f662b83eb588
https://doi.org/10.1055/s-0037-1613122
https://doi.org/10.1055/s-0037-1613122
Autor:
P. Duchaussoy, J. M. Herbert, Paul J. Schaeffer, Pierre Savi, J. P. Hérault, Andre Bernat, Petitou Maurice, Pierre-Alexandre Driguez
Publikováno v:
Thrombosis and Haemostasis. 85:852-860
SummarySR123781A, a synthetic hexadecasaccharide comprising an anti-thrombin (AT) binding domain, a thrombin binding domain, and a neutral methylated hexasaccharide sequence, was obtained from glucose through a convergent synthesis. SR123781A showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd830edfb9f4709062548fa04886ce66
https://doi.org/10.1055/s-0037-1615759
https://doi.org/10.1055/s-0037-1615759
Autor:
Pascal Bourhis, Jean-Maurice Mallet, Françoise Machetto, Philippe Duchaussoy, Maurice Petitou, J. P. Hérault, J. M. Herbert, Pierre Sinaÿ
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:2843-2846
A new synthetic route is described toward the hexasaccharide representing the heparin cofactor II binding region of dermatan sulfate. The anti-thrombin activity of this synthetic hexasaccharide is reported here for the first time. This compound is ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52f7715a02101a82b2ad2d14ff0fe383
https://doi.org/10.1016/s0960-894x(97)10082-8
https://doi.org/10.1016/s0960-894x(97)10082-8
Autor:
C. Gazanhes, J.-P. Hérault
Publikováno v:
Journal de Physique III. 3:2071-2086
The dispersion of ultrasonic waves by porous rock is studied by investigating the propagation across solid plates of limestone, in the frequency range 30 kHz-1 MHz. In this frequency range, we have observed only a single compressional wave and a shea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::305ad9f2a1426e8ad1f26fb10e08b58c
https://doi.org/10.1051/jp3:1993261
https://doi.org/10.1051/jp3:1993261
Autor:
Pierre-Alexandre Driguez, P. Duchaussoy, J. M. Herbert, Maurice Petitou, A. Bernat, J. C. Lormeau, J. P. Hérault
Publikováno v:
ChemInform. 30
In the early eighties, following breakthroughs in oligosaccharide chemistry, the total chemical synthesis of pentasaccharides has been achieved, representing the antithrombin binding domain of heparin (the active site). The selective inhibitors of co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82b1437985f306891dbc0aab092ce5ef
https://doi.org/10.1002/chin.199946273
https://doi.org/10.1002/chin.199946273
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 1(9)
Heparin-induced thrombocytopenia (HIT) is a serious secondary event encountered in the clinical use of heparin. HIT results from the consumption of platelets that are immunologically activated by antibodies directed against complexes formed by platel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7f1130dbe3605cac127b079eb9c5c1
https://pubmed.ncbi.nlm.nih.gov/12941044
https://pubmed.ncbi.nlm.nih.gov/12941044