Zobrazeno 1 - 10
of 64
pro vyhledávání: '"J P, Devissaguet"'
Publikováno v:
Annales Pharmaceutiques Françaises. 64:219-259
Established at the request of the Research Committee of the French National Academy of Pharmacy, this report on drug delivery systems (DDS) is a summary of information gathered by interviewing leaders in the pharmaceutical community and from the inte
Publikováno v:
Annals of Tropical Medicine & Parasitology. 95:529-533
Publikováno v:
Drug Development and Industrial Pharmacy. 17:7-25
It is shown that in making sustained release pellets, the effect of film laid upon film has a significant effect on the performance (dissolution characteristics) of sustained release pellets, coated with insoluble films. The penetration of liquid and
Autor:
V C, Mosqueira, P, Legrand, J L, Morgat, M, Vert, E, Mysiakine, R, Gref, J P, Devissaguet, G, Barratt
Publikováno v:
Pharmaceutical research. 18(10)
To study the pharmacokinetics and biodistribution of novel polyethyleneglycol (PEG) surface-modified poly(rac-lactide) (PLA) nanocapsules (NCs) and to investigate the influence of PEG chain length and content.The biodistribution and plasma clearance
Autor:
J P, Devissaguet
Publikováno v:
Annales pharmaceutiques francaises. 59(4)
The in vivo fate of drugs is basically regulated by the drug's physico-chemical properties, and thus depends on its chemical structure. Three successive phases describe the fate of exogenous compounds (absorption, distribution, elimination). The firs
Publikováno v:
Journal de pharmacie de Belgique. 54(5)
An hydroxypropylmethyl cellulose phthalate (HP55) pseudolatex was prepared by a nanoprecipitation method. This allows nanoparticles formation when a solution of the polymer in an organic solvent (phase S1 or organic phase) is introduced in a precipit
Publikováno v:
Pharmaceutical research. 15(7)
In a biomimetic approach to the development of drug carriers escaping early capture by phagocytes, nanoparticles made of amphiphilic copolymers of either heparin or dextran and methyl methacrylate were evaluated relative to their in vivo blood circul
Publikováno v:
Pharmaceutical research. 12(10)
Publikováno v:
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ). 45(3)
The activity of primaquine (PQ) was compared to that of PQ-loaded Poly (D,L-Lactide) (PLA) nanoparticles against Leishmania donovani. The association of PQ with PLA nanoparticles increased the antileishmanial in vitro and in vivo effects of intraveno
Publikováno v:
Pharmaceutical research. 10(5)
Following intravenous administration, the uptake of colloidal drug carriers by cells of the mononuclear phagocyte system, mainly the Kuppfer cells, may concentrate an encapsulated drug close to the liver parenchymal cells and facilitate its biliary e