Zobrazeno 1 - 10
of 68
pro vyhledávání: '"J P, Buyniski"'
Autor:
J. P. Buyniski, J. S. Gidda
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 251:G779-G785
This study examined the role of cholinergic mechanisms in esophageal smooth muscle of anesthetized opossums. Swallow-induced motility was recorded manometrically before and after treatment with physostigmine or metoclopramide. At the 5-cm site above
Autor:
J. S. Fleming, J. P. Buyniski
Publikováno v:
Cardiovascular Drug Reviews. 1:277-294
Publikováno v:
Clinical and Experimental Hypertension. 2:1039-1066
Subcutaneous administration of tiodazosin (0.1-3 mg/kg), prazosin (0.01-1 mg/kg), trimazosin (10-30 mg/kg) and phentolamine (0.1-3 mg/kg) to conscious spontaneously hypertensive rats (SHR) produced graded decreases in blood pressure with the order of
Publikováno v:
Research communications in chemical pathology and pharmacology. 23(1)
Cisplatin (cis-diammine-dichloro-platinum) administered at a dose of 3 mg/kg iv induced a reproducible and characteristic emetic response in the dog. It was characterized by a latency period (90-120 min) and multiple emetic episodes occuring within 5
Autor:
J. S. Fleming, J. P. Buyniski
Publikováno v:
VIth International Congress on Thrombosis and Haemostasis.
A potent, new anti-thrombotic agent, 6 ,7-dichloro-l,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-one hydrochloride monohydrate (BL-4162A) has been evaluated for activity against induced platelet aggregation in a series of in vitro and ex vivo experime
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 243(3)
Histamine H2 receptor antagonists have been reported to protect the gastric mucosa of animals and humans against aspirin-induced damage. It is unclear, however, whether this protective effect can be observed at doses less than those needed to markedl
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 235(1)
Isobolographic analysis was used to study in mice the combined oral analgetic action of butorphanol, a new centrally acting analgetic, and acetaminophen, an antipyretic analgetic. Combinations of butorphanol-acetaminophen exhibited analgetic effects
Publikováno v:
Research communications in chemical pathology and pharmacology. 23(1)
Prazosin produces a "first-dose" phenomenon in man clinically characterized by an exaggerated hypotensive response to the initial dose of the drug, with subsequent doses not producing this exaggerated effect. In spontaneously hypertensive rats (SHR),
Autor:
J. P. Buyniski, R. L. Cavanagh
Publikováno v:
Alimentary pharmacologytherapeutics. 3(3)
BMY-25368, 1-amino-2-[3-(3-piperidinomethylphenoxy) propylamino]-1-cyclobutene-3,4-dione, a new histamine H2-receptor antagonist, has been compared to ranitidine as an inhibitor of gastric acid secretion in the Heidenhain pouch dog. Intravenous infus
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 233(2)
Butorphanol, levo-N-cyclobutylmethyl-3, 14beta-dihydroxy-morphinan, is a new agonist-antagonist type analgetic agent which is 4 times more potent than morphine in experimental animals. Equianalgetic doses of butorphanol and morphine were compared, fo