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pro vyhledávání: '"J P, Bercz"'
Autor:
J. P. Bercz
Publikováno v:
Journal of the American College of Toxicology. 10:525-532
Ingestion of aqueous chlorine-based disinfectants has been shown earlier to cause decreased serum thyroxine levels and increased 131-I thyroid uptake in nonhuman primates. Disinfectants also were shown to immobilize iodine on gastric mucosa and cause
Autor:
Lucille M. Garner, J. P. Bercz
Publikováno v:
Journal of the American College of Toxicology. 10:533-539
Administration of drinking water treated with chlorine-based disinfectants was shown in prior studies to interfere with thyroid function of laboratory animals. One possible mechanism is that intraalimentary redox interactions between chlorine oxides
Autor:
J P Bercz
Publikováno v:
Chemical research in toxicology. 5(3)
As model reactions between unsaturated fats and water disinfectants in the GI tract, relative rates of destruction of seven polyunsaturated fatty acids (L, alpha Ln, gamma Ln, Ara, EPA, DH, and DT) by OCl- and NH2Cl were investigated in vitro. Using
Publikováno v:
Drug and chemical toxicology. 14(1-2)
Ten- and ninety-day toxicity studies of 1,2-dichlorobenzene (DCB) were conducted in male and female Sprague-Dawley rats to meet the needs of the U.S. Environmental Protection Agency for toxicity data on this chemical for use in their determination of
Publikováno v:
Drug and chemical toxicology. 13(1)
Subacute (10-day) and subchronic (90-day) toxicity studies of ethylene glycol (EG) were conducted in male and female Sprague-Dawley rats to provide the U.S. Environmental Protection Agency's (EPA) Office of Drinking Water with toxicity data for final
Publikováno v:
Environmental Health Perspectives
Toxicological studies dealing with recent findings of health effects of drinking water disinfectants are reviewed. Experiments with monkeys and rodents indicate that the biological activity of ingested disinfectants is expressed via their chemical in
Publikováno v:
Environmental Health Perspectives
Subchronic toxicities of ClO2, NaClO2, NaClO3 and NH2Cl were studied in the African Green monkeys (Cercopithecus aethiops). The chemicals were administered in drinking water during 30-60 days subchronic rising dose protocols. The only unexpected and
Publikováno v:
Environmental Health Perspectives
A large number and variety of compounds are formed in the process of chlorinating drinking water. The classes of compounds formed include trihalomethanes, haloacetic acids, haloacetonitriles, halophenols, and halopropanones. Many of the compounds hav
Publikováno v:
Research communications in chemical pathology and pharmacology. 14(2)
An automated method of sulfate analysis is described, which can detect sulfate concentrations as low as 2.5 mug per ml water. The assay is based on the reaction of sodium rhodizonate and barium forming a colored complex. Sulfate quantitavely interfer
Publikováno v:
Journal of toxicology and environmental health. 19(2)
In a previous study from this laboratory, chlorine dioxide (ClO2) treated drinking water depressed thyroxine (T4) levels in the African green monkey. The present study again demonstrated a decrease in T4 levels in the same species after 4 wk of oral