Zobrazeno 1 - 6 of 6 pro vyhledávání: '"J O, Buchanan"'
1
Effect of encainide, ODE, MODE, and flecainide on ADP/5-HT Induced platelet aggregation and in the anesthetized dog coronary artery stenosis-occlusion model of intravascular thrombosis
Autor: F D Yocca, M J Antonaccio, J S Fleming, L G Iben, J O Buchanan
Publikováno v: Cardiovascular Drugs and Therapy. 5:763-768
Encainide is a class 1C antiarrhythmic agent that is indicated for the treatment of life-threatening arrhythmias, such as sustained ventricular tachycardia. Furthermore, encainide possesses a moderate degree of antiserotonin activity, which was quant
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13fac7684166b92968a697c430999c84
https://doi.org/10.1007/bf03029752
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2
Non-prostanoid prostacyclin mimetics. 6. Derivatives of 2-[3-[2-(4,5-Diphenyl-2-oxazolyl)ethyl]phenoxy]acetic acid modified beta-to the oxazole ring
Autor: N A, Meanwell, M J, Rosenfeld, A K, Trehan, J J, Wright, C L, Brassard, J O, Buchanan, M E, Federici, J S, Fleming, M, Gamberdella, K S, Hartl
Publikováno v: Drug design and discovery. 11(1)
2-[3-[2-(4,5-Diphenyl-2-oxazolyl)ethyl]phenoxy]acetic acid, 1, has been described as a non-prostanoid PGI2 mimetic that demonstrates anti-thrombotic properties of long duration in animal models of thrombosis. The effects of substitution and modificat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dd302b8fc14602beae6edb4ff879ef0e
https://pubmed.ncbi.nlm.nih.gov/7520762
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3
Nonprostanoid prostacyclin mimetics. 2. 4,5-Diphenyloxazole derivatives
Autor: N A, Meanwell, M J, Rosenfeld, A K, Trehan, J J, Wright, C L, Brassard, J O, Buchanan, M E, Federici, J S, Fleming, M, Gamberdella, G B, Zavoico
Publikováno v: Journal of medicinal chemistry. 35(19)
4,5-Diphenyl-2-oxazolenonanoic acid (18b) was synthesized and found to inhibit ADP-induced aggregation of human platelets with an IC50 of 2.5 microM. Acid 18b displaced [3H]iloprost from human platelet membranes in a concentration-dependent fashion,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deb469276b75ebdbe0342d149073f522
https://pubmed.ncbi.nlm.nih.gov/1404230
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4
The Interaction Of Platelet Active Drugs With Prostacyclin In Vitro And Against Biolaser Induced Intravascular Thrombosis
Autor: J O Buchanan, J.P. Buyniski, J S Fleming, B T Cornish
Publikováno v: Oral Presentations.
Prostacyclin and thromboxane A2, two of the physiologically most important end products of arachidonic acid metabolism, represent a basic control system which modulates platelet function. Decreased vascular prostacyclin is believed to play a role in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5944cb588375656254893586c378ee41
https://doi.org/10.1055/s-0038-1652780
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5
EXPERIMENTAL EVALUATION OF THE RADIATION PROTECTION AFFORDED BY RESIDENTIAL STRUCTURES AGAINST DISTRIBUTED SOURCES
Autor: C. Eisenhauer, J.A. Auxier, H. E. Menker, J. O. Buchanan
Report regarding experiments made to determine the fallout-radiation protection offered by five typical residential structures located at the Nevada Test Site.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::683bca87b0066a7d4c1834a22039aedb
https://doi.org/10.2172/4276019
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