Výsledky vyhledávání

Amygdala kindling in immature rats: proconvulsant effect of the organophosphate insecticide-chlorpyrifos

Autor: J N, Wurpel, P C, Hirt, J H, Bidanset

Publikováno v: Neurotoxicology. 14(4)

Administration of the organophosphate insecticide, chlorpyrifos to immature rats exerted a proconvulsant effect on seizures induced by kindling. Chlorpyrifos was administered to 16 or 17 day old rats in a dose range of 0.3 to 10 mg/kg, subcutaneously

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bf786d74c61323944a268843840dc310
https://pubmed.ncbi.nlm.nih.gov/7513072

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Embryotoxicity and neurotoxicity in rats associated with prenatal exposure to DURSBAN

Autor: M A, Muto, F, Lobelle, J H, Bidanset, J N, Wurpel

Publikováno v: Veterinary and human toxicology. 34(6)

DURSBAN (DB; active ingredient chlorpyrifos) is a widely-used organophosphate insecticide. The teratogenic and neurotoxic potential of DB was evaluated in rats in utero by exposing embryos on days 0-7 or days 7-21 of development. These prenatal expos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1309059b8d1a3ef145f4ecd542b6323c
https://pubmed.ncbi.nlm.nih.gov/1283795

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Evidence for the involvement of nigral GABAA receptors in seizures of adult rats

Autor: E F, Sperber, J N, Wurpel, D Y, Zhao, S L, Moshé

Publikováno v: Brain Research. 480:378-382

Several studies have implicated the substantia nigra GABAergic system in the mediation of seizures in adult rats. The present study examines whether the different GABA receptors (GABAA and GABAB), are preferentially involved in this GABAergic seizure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff45f03436b1836d1e06566ce21c2e36
https://doi.org/10.1016/0006-8993(89)90211-4

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Monoclonal antibodies directed against mammalian RNA polymerase I. Identification of the catalytic center

Autor: K M, Rose, K A, Maguire, J N, Wurpel, D A, Stetler, E D, Márquez

Publikováno v: The Journal of biological chemistry. 258(21)

Mouse myeloma cells were fused with splenocytes from a mouse that had been immunized with RNA polymerase I purified from a rat hepatoma. Hybridoma cells were selected and colonies secreting antibodies directed against the enzyme were detected by anal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::871533b89b7e230899ccc0b29525b94a
https://pubmed.ncbi.nlm.nih.gov/6630216

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