Zobrazeno 1 - 10
of 24
pro vyhledávání: '"J N, Wood"'
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The cellular correlate for cold sensing has been ascribed to either Trpm8-expressing or NaV1.8-expressing neurons. Importantly, transcriptomic analysis shows that these neuronal populations are nonoverlapping. Using in vivo GCaMP imaging
Autor:
Takashi Sako, Toshifumi Yanagisawa, Kimiaki Masuda, Takahiro Sumi, Yasushi Muraki, Paul J. Tristram, Yutaka Matsubara, Ian A. Bond, P. M. Kilmartin, Denis J. Sullivan, Philip Yock, John B. Hearnshaw, J. N. Wood, Y. Furuta, Y. Kurata, K. Okajima, Fumio Abe, S. Noda, Nicholas J. Rattenbury
Publikováno v:
Monthly Notices of the Royal Astronomical Society. 364:325-334
We present the results of a search for candidate planetary transits using the Microlensing Observations in Astrophysics-I (MOA-I) microlensing survey data in the Galactic bulge. To achieve sufficient photometric precision, the analysis was confined t
Autor:
E. van Heugten, R. D. Boyd, C. E. Zier-Rush, P. L. Chang, Steven I. Smith, J. N. Wood, K.E. Lloyd, D. S. Rosero
Publikováno v:
Journal of Animal Science. 95:48
Publikováno v:
British Journal of Pharmacology
Background and Purpose The non-selective sodium channel inhibitor mexiletine has been found to be effective in several animal models of chronic pain and has become popular in the clinical setting as an orally available alternative to lidocaine. It re
Publikováno v:
Current Opinion in Genetics & Development. 9:328-332
Advances in our understanding of the activation of peripheral damage-sensing neurons (nociceptors) over the past year have been complemented by electrophysiological and imaging studies of central nervous system pain-related centres. The manipulation
Publikováno v:
Journal of Perinatology. 27:183-185
Isopropanol, a known central nervous system depressant has been reported to cause toxicity via multiple routes including ingestion, inhalation and dermal exposure. We present a case of transplacental isopropanol exposure in a neonate. A woman reporte
Autor:
R E, Sorge, M L, LaCroix-Fralish, A H, Tuttle, A, Khoutorsky, S G, Sotocinal, J-S, Austin, K, Melmed, S, Labialle, J V, Schmidt, J N, Wood, A K, Naumova, J S, Mogil
Publikováno v:
Genes, brain, and behavior. 12(4)
We recently observed a reliable phenotypic difference in the inflammatory pain sensitivity of a congenic mouse strain compared to its background strain. By constructing and testing subcongenic strains combined with gene-expression assays, we provide
Autor:
J N, Wood
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1
Once hybridoma lines have been established that secrete monoclonal antibodies of the desired specificity, it is useful to characterize the antibody subclass before mass-producing the antibody (1,2). IgG isotypes may be separated by chromatography on
Autor:
J N, Wood
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1
By far the most convenient and simple assays for screening monoclonal antibody-producing hybridomas are those utilizing solid-phase binding assays, where radiolabelled or enzyme linked antispecies antibodies are used to detect binding of the hybridom
Autor:
J N, Wood
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1
Kohler and Milsteins' (1) technique of monoclonal antibody production is now being exploited in most areas of biology. The essence of the method is to immortalize and then select for clones of plasma cells secreting antibody against a desired antigen