Zobrazeno 1 - 10 of 17 pro vyhledávání: '"J N, Vournakis"'
1
Sustained release of granulocyte-macrophage colony-stimulating factor from a modular peptide-based cancer vaccine alters vaccine microenvironment and enhances the antigen-specific T-cell response
Autor: C L, Nguyen, J T, Bui, M, Demcheva, J N, Vournakis, D J, Cole, W E, Gillanders
Publikováno v: Journal of immunotherapy (Hagerstown, Md. : 1997). 24(5)
The recent identification and molecular characterization of tumor antigens provides the opportunity to explore the rational development of peptide-based cancer vaccines. However, the response to these vaccines remains variable, and peptide-based canc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a1678a332fb7857be6c4ae8862a917e
https://pubmed.ncbi.nlm.nih.gov/11696697
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2
Characterization of a sustained-release delivery system for combined cytokine/peptide vaccination using a poly-N-acetyl glucosamine-based polymer matrix
Autor: D J, Cole, S, Gattoni-Celli, E F, McClay, J S, Metcalf, J M, Brown, N, Nabavi, D A, Newton, C B, Woolhiser, M C, Wilson, J N, Vournakis
Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 3(6)
Identification of tumor-associated antigens (TAAs) and their class I MHC-restricted epitopes now allows for the rational design of peptide-based cancer vaccines. A biocompatible system capable of sustained release of biologically relevant levels of c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a2d604cc4fd94dd5ba7696d4f217f511
https://pubmed.ncbi.nlm.nih.gov/9815761
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3
An efficient technique for obtaining sequences flanking inserted retroviruses
Autor: C S, Huckaby, R E, Kouri, M J, Lane, S M, Peshick, W T, Carroll, S M, Henderson, B D, Faldasz, P G, Waterbury, J N, Vournakis
Publikováno v: Genetic analysis, techniques and applications. 8(5)
Genomic mapping studies frequently employ retrovirus-mediated transfer of dominant selectable markers to specific target chromosomes. DNA probes containing sequences adjacent to inserted proviruses are valuable mapping tools in such studies. We have
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b12ba525c6f1a50a3f373263b63847
https://pubmed.ncbi.nlm.nih.gov/1657071
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4
Optimization of the microenvironment for mammalian cell culture in flexible collagen microspheres in a fluidized-bed bioreactor
Autor: J N, Vournakis, P W, Runstadler
Publikováno v: Biotechnology (Reading, Mass.). 17
Flexible, three-dimensional, collagen Microspheres have been developed to actively promote a natural, optimal microenvironment for large-scale tissue culture of mammalian cells. The transport of nutrients into and cell products out of the Microsphere
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8d0bf4a5b04a63bad943fc81b08b3569
https://pubmed.ncbi.nlm.nih.gov/2049545
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5
ENHANCED PRODUCTIVITY OF HYBRIDOMA AND RECOMBINANT CHO CELL CULTURES BY PLURONIC F-68 AND OTHER MEDIUM COMPONENTS, AND BY INCREASED PERFUSION RATES, IN FLUIDIZED-BED BIOREACTORS
Autor: P. W. Runstadler, A. S. Tung, J. N. Vournakis, N. G. Ray
Hybridoma and Chinese Hamster Ovary (CHO) cells are cultured in continuous fluidized-bed bioreactors. Cells are immobilized in porous, weighted collagen microspheres which are suspended in the bioreactor by the recycling of culture liquid. This paper
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9fe96cafaad372678fa8388968146cc2
https://doi.org/10.1016/b978-0-7506-1103-9.50095-0
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7
RNase H-catalyzed site-specific deadenylylation of rabbit alpha- and beta- globin mRNAs. Secondary structure of 3'-noncoding regions
Autor: Calvin P.H. Vary, J. N. Vournakis
Publikováno v: Journal of Biological Chemistry. 259:3299-3307
A general method is described for the removal of 3'-terminal polyadenylate tracts from eukaryotic messenger RNA to generate essentially homogeneous length products that can be 3'-end labeled and sequenced. Hybridization of specific oligodeoxyribonucl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b754fe5ed37bdb183ef29adac87c67d
https://doi.org/10.1016/s0021-9258(17)43294-7
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8
RNase H-catalyzed site-specific deadenylylation of rabbit alpha- and beta- globin mRNAs. Secondary structure of 3'-noncoding regions
Autor: C P, Vary, J N, Vournakis
Publikováno v: The Journal of biological chemistry. 259(5)
A general method is described for the removal of 3'-terminal polyadenylate tracts from eukaryotic messenger RNA to generate essentially homogeneous length products that can be 3'-end labeled and sequenced. Hybridization of specific oligodeoxyribonucl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::763c27b98ec071df30a812e49be2ecf0
https://pubmed.ncbi.nlm.nih.gov/6321504
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