Zobrazeno 1 - 3
of 3
pro vyhledávání: '"J N, Kew"'
Publikováno v:
British journal of pharmacology. 123(3)
1. Subunit-selective blockade of N-methyl-D-aspartate (NMDA) receptors provides a potentially attractive strategy for neuroprotection in the absence of undesirable side effects. Here, we describe a novel NR2B-selective NMDA antagonist, 4-¿3-[4-(4-fl
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 283(3)
The interaction of Ro 25-6981 with N-methyl-D-aspartate (NMDA) receptors was characterized by a variety of different tests in vitro. Ro 25-6981 inhibited 3H-MK-801 binding to rat forebrain membranes in a biphasic manner with IC50 values of 0.003 micr
Publikováno v:
Gene therapy. 1
Studies have shown that the induction of heat shock proteins (hsp's) in the CNS is protective against excitotoxicity and correlative evidence also suggest that hsp's may be protective against ischemic stress and free radical damage. In fibroblasts an