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Autor: Louis Freysz, J. N. Kanfer, Pierre Antony

Publikováno v: Neurochemical Research. 25:1073-1082

The agonist stimulation of a variety of cells results in the induction of specific lipid metabolism in nuclear membranes, supporting the hypothesis of an important role of the lipids in nuclear signal transduction. While the existence of a phosphatid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8dbe49927310e7c674f66d39518c15e3
https://doi.org/10.1023/a:1007613827552

Glycerylphosphocholine phosphocholine phosphodiesterase activity is reduced in multiple sclerosis plaques

Autor: J. N. Kanfer, W.W. Tourtellotte, L. Janzen

Publikováno v: Experimental Neurology. 109:243-246

Glycerylphosphorylcholine (GPC) phosphocholine phosphodiesterase activity (EC 3.1.4.38) is significantly reduced in multiple sclerosis plaques compared to adjacent tissue with a P less than 0.01 based upon the Student-Newman-Keuls or Tukey test. This

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40de0b38854122152a56a6da0696e41
https://doi.org/10.1016/0014-4886(90)90079-8

Amyloid beta peptide membrane perturbation is the basis for its biological effects

Autor: J N, Kanfer, G, Sorrentino, D S, Sitar

Publikováno v: Neurochemical research. 24(12)

Experimental studies have indicated that the mechanisms offered for explaining the neurotoxicity of amyloid beta peptide (AbetaP) are diverse, and include altered enzyme activities, disrupted calcium homeostasis, and increased free radical formation.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6aaea0672951f740596b6a87f5d7590b
https://pubmed.ncbi.nlm.nih.gov/10591414

Abstracts

Autor: D. R. Beniac, R. A. Ridsdale, M. D. Luckevich, T. A. Tompkins, G. Harauz, J. Sedzik, S. Hjertén, E. Brekkan, P. Lundahl, Michael B. Tropak, John C. Roder, F. Giordano, B. Chang, A. M. La Ronde, A. Al-Sabbagh, M. Kretschmer, A. Asipu, G. E. Blair, B. Mak, M. A. Moscarello, R. Doucette, K. Gratto, V. Verge, J. Yeung, A. Nazarali, P. Murphy, P. Topilko, S. Schneider-Maunoury, T. Seitanidou, A. Baron-Van Evercooren, P. Charnay, M. J. Lee, A. Brennan, A. Tabernero, Z. Dong, A. Blanchard, G. Zoidl, K. R. Jessen, R. Mirsky, E. Couve, F. Cabello, J. Krsulovic, M. Roncagliolo, J. Li, E. L. Hertzberg, J. I. Nagy, Dirk H.-H. Neuberg, Patrizia Anzini, Eric Nelles, Klaus Willecke, Melitta Schachner, Rudolf Martini, Ueli Suter, R. Ankerhold, C. A. O. Stuermer, Karen J. Chandross, W. T. Norton, L. D. Hudson, R. I. Cohen, K. Asakura, S. F. Hunter, M. Rodriguez, Rashmi Bansal, Susan Winkler, S. E. Pfeiffer, Y. S. Oh., V. W. Yong, B. H. J. Juurlink, R. W. Griebel, R. M. Devon, A. Khorchid, G. Almazan, H.-N. Liu, G. W. Konat, Gu Jin, R. C. Wiggins, S. K. Thorburne, B. L. Bartnik, H. Marrif, L. Hertz, S. E. Jelinski, J. Y. Yager, M. R. Del Bigio, J. N. Kanfer, H. L. Weiner, P. A. Nelson, J. K. Dyer, J. Bourque, J. D. Steeves, Monika Labes, Arthur Roach, Parker L. Andersen, David J. Schreyer, J. L. Vanderluit, A. Peterson, W. Tetzlaff, C. O. Hanemann, A. Gabreëls-Festen, H. W. Mueller, L. A. Karchewski, V. M. K. Verge, M. Foldvari, M. R. Jaafari

Publikováno v: Cell Biology and Pathology of Myelin ISBN: 9780306455957

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ccba320f138951e01d5cfe8aaa3194c
https://doi.org/10.1007/978-1-4615-5949-8_34

Magnetic resonance spectroscopy and its application to aging and Alzheimer's disease

Autor: R J, McClure, J N, Kanfer, K, Panchalingam, W E, Klunk, J W, Pettegrew

Publikováno v: Neuroimaging clinics of North America. 5(1)

This is a review of magnetic resonance (MR) spectroscopy and its application to aging and Alzheimer's disease (AD). Examinations of perchloric acid extracts of AD brain tissue by MR spectroscopy reveal elevated levels of phosphomonoesters, phosphodie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9730f10498674f15be903177f53c5076
https://pubmed.ncbi.nlm.nih.gov/7743086