Zobrazeno 1 - 10
of 17
pro vyhledávání: '"J N, Finkelstein"'
Publikováno v:
Journal of Lipid Research, Vol 19, Iss 4, Pp 467-477 (1978)
Lung cell-free homogenate, which contains about twice the units of phosphatidate phosphohydrolase per mg of protein compared to liver, was fractionated by differential centrifugation and the fractions were assayed for phosphatidate phosphohydrolase a
Externí odkaz:
https://doaj.org/article/5c163a4b59224b9c8f2ba858d60af43f
Publikováno v:
Research report (Health Effects Institute). (96)
Ambient fine particles consist of ultrafine particles (100 nm) and accumulation-mode particles (approximately 100 to 1,000 nm). Our hypothesis that ultrafine particles can have adverse effects in humans is based on results of our earlier studies with
Publikováno v:
Inhalation toxicology. 12(3)
Neonatal animals of some mammalian species are more tolerant to several pulmonary oxidative stress-inducing toxicants than adults. Our initial studies during hyperoxic injury demonstrated a rapid chemokine and cytokine response early in the developme
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 46(2)
Inhaled endotoxin (lipopolysaccharide, LPS) can induce acute lung injury and at high doses may lead to respiratory distress syndrome. Using a mouse model of acute lung inflammation induced by inhalation of low doses of LPS we examined the kinetics of
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 78(4)
Epithelial repair following acute lung injury involves proliferation and differentiation of existing Clara cells and type II cells. Other mechanisms of epithelial repair may be involved in particularly severe cases. We used epithelial cell-specific m
Publikováno v:
Radiation research. 145(6)
Fibrosis, characterized by the accumulation of collagen, is a consequence of a chronic inflammatory response. The purpose of this study was to determine if tumor necrosis factor alpha (TNF-alpha), interleukin-1 alpha (IL-1 alpha) and IL-1 beta mRNA e
Publikováno v:
Radiation research. 142(2)
Fibrosis, characterized by the accumulation of collagen, is a late result of thoracic irradiation. The purpose of this study was to determine if extracellular matrix protein and transforming growth factor beta mRNA expression are altered late in the
Publikováno v:
Neurotoxicology. 15(4)
Although alterations in dopaminergic function represent a potential neurochemical basis of Pb-induced behavioral deficits, the impact of postnatal Pb exposure on DA systems has not been adequately delineated. This study examined the effects of postna
Publikováno v:
Clinics in perinatology. 19(3)
Those factors that determine whether tissue injury is followed by regeneration and repair or irreversible destruction and fibrosis are only now being elucidated. This article examines the lung's response to injury, the prominent role of polypeptide g
Publikováno v:
Research report (Health Effects Institute). (43)
These studies were undertaken to evaluate short-term respiratory effects and identify markers of nitrogen dioxide toxicity during exposures designed to approximate realistic conditions. With the development of bronchoalveolar lavage as a clinical inv