Zobrazeno 1 - 10
of 351
pro vyhledávání: '"J Mole"'
Autor:
Yasmin Soltanzadeh-Naderi, Annika Reintam Blaser, Martin Björck, Alexandre Nuzzo, Joel Starkopf, Alastair Forbes, Marko Murruste, Kadri Tamme, Peep Talving, Anna-Liisa Voomets, Merli Koitmäe, Miklosh Bala, Zsolt Bodnar, Dumitru Casian, Zaza Demetrashvili, Mario D’Oria, Virginia Dúran Muñoz-Cruzado, Hanne Fuglseth, Moran Hellerman Itzhaki, Benjamin Hess, Karri Kase, Kristoffer Lein, Matthias Lindner, Cecilia I. Loudet, Damian J. Mole, Sten Saar, Maximilian Scheiterle, Kenneth Voon, Jonas Tverring, Stefan Acosta
Publikováno v:
Diagnostics, Vol 14, Iss 23, p 2705 (2024)
Background: There are no clinical or laboratory markers that can diagnose acute mesenteric ischemia (AMI) accurately. This study aimed to find differences in clinical and laboratory markers between arterial occlusive AMI and other acute abdominal dis
Externí odkaz:
https://doaj.org/article/29c5c26bab2e4ff88cf9f16f8295074a
Autor:
Noelle J. Molé
Psychological harassment at work, or'mobbing,'has become a significant public policy issue in Italy and elsewhere in Europe. Mobbing has given rise to specialized counseling clinics, a new field of professional expertise, and new labor laws. For Noel
Autor:
Marc‐Olivier Deguise, Giovanni Baranello, Chiara Mastella, Ariane Beauvais, Jean Michaud, Alessandro Leone, Ramona De Amicis, Alberto Battezzati, Christopher Dunham, Kathryn Selby, Jodi Warman Chardon, Hugh J. McMillan, Yu‐Ting Huang, Natalie L. Courtney, Alannah J. Mole, Sabrina Kubinski, Peter Claus, Lyndsay M. Murray, Melissa Bowerman, Thomas H. Gillingwater, Simona Bertoli, Simon H. Parson, Rashmi Kothary
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 8, Pp 1519-1532 (2019)
Abstract Objective Spinal muscular atrophy (SMA) is an inherited neuromuscular disorder leading to paralysis and subsequent death in young children. Initially considered a motor neuron disease, extra‐neuronal involvement is increasingly recognized.
Externí odkaz:
https://doaj.org/article/fc27db022435433fb87c7d2bb5016994
Autor:
Xiaozhong Zheng, Ailiang Zhang, Margaret Binnie, Kris McGuire, Scott P. Webster, Jeremy Hughes, Sarah E. M. Howie, Damian J. Mole
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 2, Pp 1-14 (2019)
Kidney disease: drug target for acute injury following reperfusion Inhibition of a metabolic enzyme linked to inflammation could be a novel treatment approach for sudden kidney failure following a “reperfusion” injury caused by blood flow returni
Externí odkaz:
https://doaj.org/article/ecd0d27bbf6d459ca7a317a69807af0d
Autor:
Catriona Graham, Chiara Ventre, Damian J Mole, Scott Semple, Kim Walker, David Morris, Audrey White, Jill MacLeod, Ahmed E Sherif, Rory McFadyen, Julia Boyd, Margaret Glenwright, Xiaozhong Zheng, Laura McFadyen, Emma Connon, Dimitrios Damaskos, Michelle Steven, Anthony Wackett, Euan Thomson, David C Cameron, Shaun Baxter, Saskia Clark-Stewart
Publikováno v:
BMJ Open, Vol 10, Iss 12 (2020)
Introduction Survivors of acute pancreatitis (AP) have shorter overall survival and increased incidence of new-onset cardiovascular, respiratory, liver and renal disease, diabetes mellitus and cancer compared with the general population, but the mech
Externí odkaz:
https://doaj.org/article/5e1ba1ed28de4d92b86bd37baa3fd334
Autor:
Soudabeh Rad Pour, Hiromasa Morikawa, Narsis A. Kiani, David Gomez-Cabrero, Alistair Hayes, Xiaozhong Zheng, Maria Pernemalm, Janne Lehtiö, Damian J. Mole, Johan Hansson, Hanna Eriksson, Jesper Tegnér
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Dysregulation of the kynurenine pathway has been regarded as a mechanism of tumor immune escape by the enzymatic activity of indoleamine 2, 3 dioxygenase and kynurenine production. However, the immune-modulatory properties of other kynurenine metabol
Externí odkaz:
https://doaj.org/article/a3a931a5829443e5bdad59c2b11dd4a5
Autor:
Damian J Mole, Jonathan A Fallowfield, Ahmed E Sherif, Timothy Kendall, Scott Semple, Matt Kelly, Gerard Ridgway, John J Connell, John McGonigle, Rajarshi Banerjee, J Michael Brady, Xiaozhong Zheng, Michael Hughes, Lucile Neyton, Joanne McClintock, Garry Tucker, Hilary Nailon, Dilip Patel, Anthony Wackett, Michelle Steven, Fenella Welsh, Myrddin Rees, HepaT1ca Study Group
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0238568 (2020)
The risk of poor post-operative outcome and the benefits of surgical resection as a curative therapy require careful assessment by the clinical care team for patients with primary and secondary liver cancer. Advances in surgical techniques have impro
Externí odkaz:
https://doaj.org/article/efe9d90ff055482e9e64951c38de830b
Publikováno v:
ACS Omega, Vol 3, Iss 3, Pp 2564-2568 (2018)
Externí odkaz:
https://doaj.org/article/7c38761819254d0d9d5cb59327531b0a
Autor:
Dolors Puigoriol-Illamola, Júlia Companys-Alemany, Kris McGuire, Natalie Z. M. Homer, Rosana Leiva, Santiago Vázquez, Damian J. Mole, Christian Griñán-Ferré, Mercè Pallàs
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 1040 (2021)
Impaired glucocorticoid (GC) signaling is a significant factor in aging, stress, and neurodegenerative diseases such as Alzheimer’s disease. Therefore, the study of GC-mediated stress responses to chronic moderately stressful situations, which occu
Externí odkaz:
https://doaj.org/article/215b208ba57149ba94865e604599c448
Autor:
Jonathan P. Hutchinson, Paul Rowland, Mark R. D. Taylor, Erica M. Christodoulou, Carl Haslam, Clare I. Hobbs, Duncan S. Holmes, Paul Homes, John Liddle, Damian J. Mole, Iain Uings, Ann L. Walker, Scott P. Webster, Christopher G. Mowat, Chun-wa Chung
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Kynurenine-3-monooxygenase (KMO) is an emerging clinical target for treatment of neurodegenerative diseases and acute pancreatitis. Here, the authors report potent inhibitors that bind KMO in an unexpected conformation, offering structural and mechan
Externí odkaz:
https://doaj.org/article/6a2d1e05cbf54050aa6e26f4834e4b9a