Zobrazeno 1 - 10
of 107
pro vyhledávání: '"J Michael, Overton"'
Publikováno v:
Brain Research. 1442:15-24
Combined amylin+leptin (AMN+LEP) can reduce diet induced obesity and is very effective in combating LEP resistance. The purpose of this study was to evaluate the effect of AMN+LEP on central histaminergic signaling in lean and obese rats. Male rats w
Publikováno v:
Regulatory Peptides. 154:60-68
We examined the possibility that chronic, low-dose peripheral leptin infusion would inhibit food intake but not increase blood pressure. Male Fisher Brown Norway (FBNF1) and Sprague–Dawley (SD) rats were instrumented for cardiovascular telemetry, h
Publikováno v:
Regulatory Peptides. 139:23-30
Melanin-concentrating hormone (MCH) is a cyclic 19-amino acid neuropeptide exclusively synthesized in the lateral hypothalamic area (LHA) and the zona incerta (ZI) that has been implicated in the regulation of energy balance. Despite what is known ab
Publikováno v:
Physiology & Behavior. 88:523-528
Estradiol exerts an inhibitory effect on food intake via interactions with anorexigenic peptides, like cholecystokinin, that function to decrease meal size. It is currently unknown whether estradiol also interacts with orexigenic compounds implicated
Publikováno v:
Neuroendocrinology. 83:69-76
Inhibition of hypothalamic thyrotropin-releasing hormone (TRH) neuronal activity is a well-established adaptation to caloric restriction (CR) that suppresses pituitary secretion of thyroid-stimulating hormone, but may also participate in modulation o
Publikováno v:
Physiology & Behavior. 86:324-330
We studied the effect of arcuate nucleus (ARC) lesions induced pharmacologically by the perinatal treatment of monosodium l -glutamate (MSG) on the cardiovascular, metabolic, and behavioral responses to fasting. Saline and MSG-treated male Sprague–
Publikováno v:
Metabolism. 53:727-732
The trace metal zinc (Zn) is essential for the catalytic activity of many enzymes involved in energy nutrient metabolism and appears to regulate hormones, such as insulin, leptin, and thyroid hormone that play key roles in metabolism. Thus, this stud
Publikováno v:
Physiology (Bethesda, Md.). 29(6)
Does it matter that rodents used as preclinical models of human biology are routinely housed below their thermoneutral zone? We compile evidence showing that such rodents are cold-stressed, hypermetabolic, hypertensive, sleep-deprived, obesity-resist
Autor:
Joshua M. Hare, Brittany Griffin, David Dweck, Jingsheng Liang, Crystal Dawn Badger, Frank D. Fincham, Audrey N. Chang, Raul A Dulce, Jose R. Pinto, Marcos A. Sanchez-Gonzalez, Mohamed Kabbaj, Andrew P. Koutnik, J. Michael Overton, Edda L. Ruiz
Publikováno v:
The Journal of biological chemistry. 289(33)
The cardiac troponin I (cTnI) R21C (cTnI-R21C) mutation has been linked to hypertrophic cardiomyopathy and renders cTnI incapable of phosphorylation by PKA in vivo. Echocardiographic imaging of homozygous knock-in mice expressing the cTnI-R21C mutati
Publikováno v:
Nutrition Research. 18:1581-1594
We examined the effects of short-term food deprivation on directly measured blood pressure and sympathetic support of blood pressure in male (n=7, 231±7 g) and female (n=9, 193±4 g) spontaneously hypertensive rats (SHR, Charles River). Carotid arte