Zobrazeno 1 - 10
of 446
pro vyhledávání: '"J McSorley"'
Autor:
Florent Colomb, Abhishek Jamwal, Adefunke Ogunkanbi, Tania Frangova, Alice R Savage, Sarah Kelly, Gavin J Wright, Matthew K Higgins, Henry J McSorley
Publikováno v:
eLife, Vol 13 (2024)
The parasitic nematode Heligmosomoides polygyrus bakeri secretes the HpARI family, which bind to IL-33, either suppressing (HpARI1 and HpARI2) or enhancing (HpARI3) responses to the cytokine. We previously showed that HpARI2 also bound to DNA via its
Externí odkaz:
https://doaj.org/article/9403e694d6fd4968991cbb1e6f8f000a
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract IL-33 plays a significant role in inflammation, allergy, and host defence against parasitic helminths. The model gastrointestinal nematode Heligmosomoides polygyrus bakeri secretes the Alarmin Release Inhibitor HpARI2, an effector protein th
Externí odkaz:
https://doaj.org/article/85989ed30a0b45e5bbb0d7c6e41dd367
Autor:
Abigail E. Reese, Fabio de Moliner, Lorena Mendive-Tapia, Sam Benson, Erkin Kuru, Thomas Bridge, Josh Richards, Jonathan Rittichier, Takanori Kitamura, Amit Sachdeva, Henry J. McSorley, Marc Vendrell
Publikováno v:
ACS Central Science, Vol 10, Iss 1, Pp 143-154 (2023)
Externí odkaz:
https://doaj.org/article/f1eb7defdb8e48c082ebe0672b13f460
Autor:
Benjamin Lenz, Alexandra Ehrens, Jesuthas Ajendra, Frederic Risch, Joséphine Gal, Anna-Lena Neumann, Julia J Reichwald, Wiebke Strutz, Henry J McSorley, Coralie Martin, Achim Hoerauf, Marc P Hübner
Publikováno v:
PLoS Pathogens, Vol 20, Iss 3, p e1012071 (2024)
BackgroundEosinophilia is a hallmark of helminth infections and eosinophils are essential in the protective immune responses against helminths. Nevertheless, the distinct role of eosinophils during parasitic filarial infection, allergy and autoimmune
Externí odkaz:
https://doaj.org/article/81dcb609f4764a5982be20406e4ed3fc
Autor:
Piotr Pawel Janas, Caroline Chauché, Patrick Shearer, Georgia Perona-Wright, Henry J McSorley, Jürgen Schwarze
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0297585 (2024)
Airway epithelial cells (AECs) play a key role in maintaining lung homeostasis, epithelium regeneration and the initiation of pulmonary immune responses. To isolate and study murine AECs investigators have classically used short and hot (1h 37°C) di
Externí odkaz:
https://doaj.org/article/7eef7a8a675940f1a051061377e10cbb
Autor:
Jordan A Rixon, Kevin D Fong, Claire Morris, Alana T Nguyen, Claire E Depew, Stephen J McSorley
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011914 (2024)
Chlamydia vaccine approaches aspire to induce Th1 cells for optimal protection, despite the fact that there is no direct evidence demonstrating Th1-mediated Chlamydia clearance from the female reproductive tract (FRT). We recently reported that T-bet
Externí odkaz:
https://doaj.org/article/d7f6c3d59cc04578bb2272178b7cf035
Autor:
Yashavanth Shaan Lakshmanappa, Sonny R. Elizaldi, Jamin W. Roh, Brian A. Schmidt, Timothy D. Carroll, Kourtney D. Weaver, Justin C. Smith, Anil Verma, Jesse D. Deere, Joseph Dutra, Mars Stone, Sergej Franz, Rebecca Lee Sammak, Katherine J. Olstad, J. Rachel Reader, Zhong-Min Ma, Nancy K. Nguyen, Jennifer Watanabe, Jodie Usachenko, Ramya Immareddy, JoAnn L. Yee, Daniela Weiskopf, Alessandro Sette, Dennis Hartigan-O’Connor, Stephen J. McSorley, John H. Morrison, Nam K. Tran, Graham Simmons, Michael P. Busch, Pamela A. Kozlowski, Koen K. A. Van Rompay, Christopher J. Miller, Smita S. Iyer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Induction of CD4 T follicular helper (Tfh) cells is important for antibody responses to viral infections. Here, the authors show in a rhesus macaque model of mild COVID-19 that SARS-CoV-2 infection results in transient accumulation of proliferating T
Externí odkaz:
https://doaj.org/article/0b3b94e948d5442aa6b0f00f729b8c20
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1010333 (2022)
Protective immune responses to Chlamydia infection within the female reproductive tract (FRT) are incompletely understood. MHC class II-restricted CD4 Th1 responses are believed to be vital for bacterial clearance due to their capacity to secrete IFN
Externí odkaz:
https://doaj.org/article/af871a870ead42d1876e36416cc19b3f
Autor:
Newton G. Peres, Nancy Wang, Paul Whitney, Sven Engel, Meghanashree M. Shreenivas, Ian Comerford, Dianna M. Hocking, Anna B. Erazo, Irmgard Förster, Andreas Kupz, Thomas Gebhardt, Shaun R. McColl, Stephen J. McSorley, Sammy Bedoui, Richard A. Strugnell
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10 (2021)
While Salmonella enterica is seen as an archetypal facultative intracellular bacterial pathogen where protection is mediated by CD4+ T cells, identifying circulating protective cells has proved very difficult, inhibiting steps to identify key antigen
Externí odkaz:
https://doaj.org/article/2cba44dd59ea4403844f41d34e30910e
Autor:
William N. G. Moore, Timothy J. McSorley, Alexandre Vincent, Joseph W. Ziller, Luis A. Jauregui, William J. Evans
Publikováno v:
ACS Applied Nano Materials. 6:6461-6466
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e8fd711a7605ce182cab8dc95809639
https://doi.org/10.1021/acsanm.3c00662
https://doi.org/10.1021/acsanm.3c00662