Genomic approaches in the search for molecular biomarkers in chronic kidney disease

Autor: M. Cañadas-Garre, K. Anderson, J. McGoldrick, A. P. Maxwell, A. J. McKnight

Publikováno v: Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-44 (2018)

Abstract Background Chronic kidney disease (CKD) is recognised as a global public health problem, more prevalent in older persons and associated with multiple co-morbidities. Diabetes mellitus and hypertension are common aetiologies for CKD, but IgA

Externí odkaz: https://doaj.org/article/41179ee3f7a84822b6966e726e739f35

Centers for Mendelian Genomics: A decade of facilitating gene discovery

Autor: Samantha M. Baxter, Jennifer E. Posey, Nicole J. Lake, Nara Sobreira, Jessica X. Chong, Steven Buyske, Elizabeth E. Blue, Lisa H. Chadwick, Zeynep H. Coban-Akdemir, Kimberly F. Doheny, Colleen P. Davis, Monkol Lek, Christopher Wellington, Shalini N. Jhangiani, Mark Gerstein, Richard A. Gibbs, Richard P. Lifton, Daniel G. MacArthur, Tara C. Matise, James R. Lupski, David Valle, Michael J. Bamshad, Ada Hamosh, Shrikant Mane, Deborah A. Nickerson, Heidi L. Rehm, Anne O’Donnell-Luria, Marcia Adams, François Aguet, Gulsen Akay, Peter Anderson, Corina Antonescu, Harindra M. Arachchi, Mehmed M. Atik, Christina A. Austin-Tse, Larry Babb, Tamara J. Bacus, Vahid Bahrambeigi, Suganthi Balasubramanian, Yavuz Bayram, Arthur L. Beaudet, Christine R. Beck, John W. Belmont, Jennifer E. Below, Kaya Bilguvar, Corinne D. Boehm, Eric Boerwinkle, Philip M. Boone, Sara J. Bowne, Harrison Brand, Kati J. Buckingham, Alicia B. Byrne, Daniel Calame, Ian M. Campbell, Xiaolong Cao, Claudia Carvalho, Varuna Chander, Jaime Chang, Katherine R. Chao, Ivan K. Chinn, Declan Clarke, Ryan L. Collins, Beryl Cummings, Zain Dardas, Moez Dawood, Kayla Delano, Stephanie P. DiTroia, Harshavardhan Doddapaneni, Haowei Du, Renqian Du, Ruizhi Duan, Mohammad Eldomery, Christine M. Eng, Eleina England, Emily Evangelista, Selin Everett, Jawid Fatih, Adam Felsenfeld, Laurent C. Francioli, Christian D. Frazar, Jack Fu, Emmanuel Gamarra, Tomasz Gambin, Weiniu Gan, Mira Gandhi, Vijay S. Ganesh, Kiran V. Garimella, Laura D. Gauthier, Danielle Giroux, Claudia Gonzaga-Jauregui, Julia K. Goodrich, William W. Gordon, Sean Griffith, Christopher M. Grochowski, Shen Gu, Sanna Gudmundsson, Stacey J. Hall, Adam Hansen, Tamar Harel, Arif O. Harmanci, Isabella Herman, Kurt Hetrick, Hadia Hijazi, Martha Horike-Pyne, Elvin Hsu, Jianhong Hu, Yongqing Huang, Jameson R. Hurless, Steve Jahl, Gail P. Jarvik, Yunyun Jiang, Eric Johanson, Angad Jolly, Ender Karaca, Michael Khayat, James Knight, J. Thomas Kolar, Sushant Kumar, Seema Lalani, Kristen M. Laricchia, Kathryn E. Larkin, Suzanne M. Leal, Gabrielle Lemire, Richard A. Lewis, He Li, Hua Ling, Rachel B. Lipson, Pengfei Liu, Alysia Kern Lovgren, Francesc López-Giráldez, Melissa P. MacMillan, Brian E. Mangilog, Stacy Mano, Dana Marafi, Beth Marosy, Jamie L. Marshall, Renan Martin, Colby T. Marvin, Michelle Mawhinney, Sean McGee, Daniel J. McGoldrick, Michelle Mehaffey, Betselote Mekonnen, Xiaolu Meng, Tadahiro Mitani, Christina Y. Miyake, David Mohr, Shaine Morris, Thomas E. Mullen, David R. Murdock, Mullai Murugan, Donna M. Muzny, Ben Myers, Juanita Neira, Kevin K. Nguyen, Patrick M. Nielsen, Natalie Nudelman, Emily O’Heir, Melanie C. O’Leary, Chrissie Ongaco, Jordan Orange, Ikeoluwa A. Osei-Owusu, Ingrid S. Paine, Lynn S. Pais, Justin Paschall, Karynne Patterson, Davut Pehlivan, Benjamin Pelle, Samantha Penney, Jorge Perez de Acha Chavez, Emma Pierce-Hoffman, Cecilia M. Poli, Jaya Punetha, Aparna Radhakrishnan, Matthew A. Richardson, Eliete Rodrigues, Gwendolin T. Roote, Jill A. Rosenfeld, Erica L. Ryke, Aniko Sabo, Alice Sanchez, Isabelle Schrauwen, Daryl A. Scott, Fritz Sedlazeck, Jillian Serrano, Chad A. Shaw, Tameka Shelford, Kathryn M. Shively, Moriel Singer-Berk, Joshua D. Smith, Hana Snow, Grace Snyder, Matthew Solomonson, Rachel G. Son, Xiaofei Song, Pawel Stankiewicz, Taylorlyn Stephan, V. Reid Sutton, Abigail Sveden, Diana Cornejo Sánchez, Monica Tackett, Michael Talkowski, Machiko S. Threlkeld, Grace Tiao, Miriam S. Udler, Laura Vail, Zaheer Valivullah, Elise Valkanas, Grace E. VanNoy, Qingbo S. Wang, Gao Wang, Lu Wang, Michael F. Wangler, Nicholas A. Watts, Ben Weisburd, Jeffrey M. Weiss, Marsha M. Wheeler, Janson J. White, Clara E. Williamson, Michael W. Wilson, Wojciech Wiszniewski, Marjorie A. Withers, Dane Witmer, Lauren Witzgall, Elizabeth Wohler, Monica H. Wojcik, Isaac Wong, Jordan C. Wood, Nan Wu, Jinchuan Xing, Yaping Yang, Qian Yi, Bo Yuan, Jordan E. Zeiger, Chaofan Zhang, Peng Zhang, Yan Zhang, Xiaohong Zhang, Yeting Zhang, Shifa Zhang, Huda Zoghbi, Igna van den Veyver

Publikováno v: Genet Med

PURPOSE: Mendelian disease genomic research has undergone a massive transformation over the past decade. With increasing availability of exome and genome sequencing, the role of Mendelian research has expanded beyond data collection, sequencing, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b797c7738329d28c572a5aa99b98ff15
https://doi.org/10.1016/j.gim.2021.12.005

Perfluoroalkyl acids in the Canadian environment: Multi-media assessment of current status and trends

Autor: Sarah B. Gewurtz, Sean M. Backus, Amila O. De Silva, Lutz Ahrens, Alain Armellin, Marlene Evans, Susan Fraser, Melissa Gledhill, Paula Guerra, Tom Harner, Paul A. Helm, Hayley Hung, Nav Khera, Min Gu Kim, Martha King, Sum Chi Lee, Robert J. Letcher, Pamela Martin, Chris Marvin, Daryl J. McGoldrick, Anne L. Myers, Magella Pelletier, Joe Pomeroy, Eric J. Reiner, Myriam Rondeau, Marie-Claude Sauve, Mark Sekela, Mahiba Shoeib, Daniel W. Smith, Shirley Anne Smyth, John Struger, Doug Spry, Jim Syrgiannis, Jasmine Waltho

Publikováno v: Environment International, Vol 59, Iss , Pp 183-200 (2013)

In Canada, perfluoroalkyl acids (PFAAs) have been the focus of several monitoring programs and research and surveillance studies. Here, we integrate recent data and perform a multi-media assessment to examine the current status and ongoing trends of

Externí odkaz: https://doaj.org/article/b627db630b444371ae737b60c5f789b5

75 How ACTIVE IS ACTIVE? physical Activity Levels in Children living with Obesity

Autor: A Long, A McClean, B O’Connor, J Gawley, R Graham, N Khan, A Harbinson, J McGoldrick, J Gordon

Publikováno v: Abstracts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d03d4098468b0d83955ca0a981cc3cbc
https://doi.org/10.1136/archdischild-2021-europaediatrics.75

Distinguishing Ore Deposit Type and Barren Sedimentary Pyrite Using Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry Trace Element Data and Statistical Analysis of Large Data Sets

Autor: Ross R. Large, Daniel D. Gregory, Timothy W. Lyons, Jeffrey A. Steadman, M. C. Figueroa, Michael J. Baker, Mathew J. Cracknell, Stephen Kuhn, Adrian Fabris, Peter J. McGoldrick, Nathan Fox, IA Belousov, Valery V. Maslennikov

Publikováno v: Economic Geology. 114:771-786

Faced with ongoing depletion of near-surface ore deposits, geologists are increasingly required to explore for deep deposits or those lying beneath surface cover. The result is increased drilling costs and a need to maximize the value of the drill ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::876dcc0565ba7118b46a53dc321792d1
https://doi.org/10.5382/econgeo.4654