Zobrazeno 1 - 10 of 491 pro vyhledávání: '"J Maclouf"'
1
Fate of etiproston, a synthetic analogue of PGF2α, in cows
Autor: P Brune, P Guillot, Alain Pruvost, P Archimbault, Jean-Marc Grognet, J Maclouf, H Benech, R C Murphys
Publikováno v: Journal of Veterinary Pharmacology and Therapeutics. 17:339-344
The pharmacokinetics and metabolic fate of labelled compounds were investigated after intramuscular administration of 3H-radiolabelled etiproston to nine cows. Elimination was rapid (t 1/2 beta = 2.8 h). Forty-eight h after administration 92.6% of th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a604a3314c85871f763c08f654e36d2
https://doi.org/10.1111/j.1365-2885.1994.tb00256.x
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2
Cyclooxygenase-independent induction of p21WAF-1/cip1, apoptosis and differentiation by L-745,337, a selective PGH synthase-2 inhibitor, and salicylate in HT-29 cells
Autor: G, Santini, M G, Sciulli, R, Marinacci, O, Fusco, L, Spoletini, A, Pace, A, Ricciardulli, C, Natoli, A, Procopio, J, Maclouf, P, Patrignani
Publikováno v: Apoptosis : an international journal on programmed cell death. 4(3)
In order to dissect out cyclooxygenase-dependent from cyclooxygenase-independent mechanisms in the antiproliferative effects of selective prostaglandin H synthase (PGHS)-2 inhibitors, we compared the effects of L-745,337 (a highly selective PGHS-2 in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a519be5610fe8e1102025ac5cc45d31f
https://pubmed.ncbi.nlm.nih.gov/14634277
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3
Induction of cyclo-oxygenase-2 in human endothelial cells by SIN-1 in the absence of prostaglandin production
Autor: S, Eligini, A, Habib, M, Lebret, C, Créminon, S, Lévy-Toledano, J, Maclouf
Publikováno v: British journal of pharmacology. 133(7)
Nitric oxide (NO) regulates cyclo-oxygenase (COX) activity in various cell systems and reports conflict in regard to its stimulatory versus inhibitory role. Incubation of human umbilical vein endothelial cells (HUVEC) with SIN-1 (3-morpholinosydnonim
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::29cc12b8534cc534183f365c0a018733
https://pubmed.ncbi.nlm.nih.gov/11487528
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4
Enhanced expression of haem oxygenase-1 by nitric oxide and antiinflammatory drugs in NIH 3T3 fibroblasts
Autor: M J, Alcaraz, A, Habib, M, Lebret, C, Créminon, S, Lévy-Toledano, J, Maclouf
Publikováno v: British journal of pharmacology. 130(1)
1. Haem oxygenase-1 (HO-1) can exert protective effects against oxidative stress and inflammation. Fibroblasts participate in inflammatory responses where they produce high levels of prostaglandins (PGs) and nitric oxide (NO). However, little is know
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::74427b96947011c8d002fd10d08f571f
https://pubmed.ncbi.nlm.nih.gov/10780998
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8
A chronic hypercoagulable state in patients with beta-thalassaemia major is already present in childhood
Autor: A, Eldor, R, Durst, E, Hy-Am, A, Goldfarb, S, Gillis, E A, Rachmilewitz, A, Abramov, J, MacLouf, Y C, Godefray, E, De Raucourt, M C, Guillin
Publikováno v: British journal of haematology. 107(4)
A higher than normal incidence of thromboembolic events has been observed in adult patients with beta-thalassaemia major (TM) and certain haemostatic anomalies found in these patients suggest the existence of a chronic hypercoagulable state. Thalassa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::414d3c96599fd10c4e4099d82e7a6539
https://pubmed.ncbi.nlm.nih.gov/10606878
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9
Differential effects of long chain n-3 fatty acids on the expression of PGH synthase isoforms in bovine aortic endothelial cells
Autor: Michel Lagarde, J. Maclouf, S. Dalloz, M. Gilbert
Publikováno v: Prostaglandins, leukotrienes, and essential fatty acids. 60(5-6)
Primary cultures of bovine aortic endothelial cells were used at confluency to evaluate the effect of eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids on the expression of both the constitutive and inducible isoforms of PGH synthase (PGHS), PGH
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::325989529909469ab36765001d225970
https://pubmed.ncbi.nlm.nih.gov/10471122
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10
Early expression of cyclo-oxygenase-2 during sporadic colorectal carcinogenesis
Autor: X, Hao, A E, Bishop, M, Wallace, H, Wang, T C, Willcocks, J, Maclouf, J M, Polak, S, Knight, I C, Talbot
Publikováno v: The Journal of pathology. 187(3)
Regular administration of non-steroidal anti-inflammatory drugs (NSAIDs) may reduce the incidence of colorectal cancer by targeting cyclo-oxygenase-2 (Cox-2), a key enzyme in arachidonic acid metabolism. To evaluate the role of Cox-2 in sporadic colo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::028d62e7d9917f5a27077eae6ceccdaf
https://pubmed.ncbi.nlm.nih.gov/10398082
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